Facilitators and barriers for lifestyle change in people with prediabetes: a meta-synthesis of qualitative studies

Skoglund, Gyri; Nilsson, Birgitta; Olsen, Cecilie Fromholt; Bergland, Astrid; Hilde, Gunvor

doi:10.1186/s12889-022-12885-8

Cited by 46 publications

(41 citation statements)

References 76 publications

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“…However, the best-designed lifestyle intervention is useless if the participants are not comfortable with it. Due to individual barriers, or if participants do not see further benefit for their HRQOL in addition to the weight reduction, the lifestyle alteration might not be integrated into everyday life in the long term [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

High-Protein, Low-Glycaemic Meal Replacement Improves Physical Health-Related Quality of Life in High-Risk Persons for Metabolic Syndrome—A Subanalysis of the Randomised-Controlled ACOORH Trial

Kempf¹,

Röhling²,

Banzer

et al. 2022

Nutrients

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While obesity impairs health-related quality of life (HRQOL), lifestyle interventions targeting weight reduction have been effective in improving HRQOL. Therefore, we hypothesised that a meal replacement-based lifestyle intervention, which has been shown to successfully reduce weight, would also improve HRQOL more effectively than a lifestyle intervention alone. In the international, multicenter, randomised-controlled ACOORH-trial (Almased-Concept-against- Overweight-and-Obesity-and-Related-Health-Risk), overweight or obese participants with elevated risk for metabolic syndrome (n = 463) were randomised into two groups. Both groups received telemonitoring devices and nutritional advice. The intervention group additionally used a protein-rich, low-glycaemic meal replacement for 6 months. HRQOL was estimated at baseline, after 3 and 12 months, using the SF-36 questionnaire, and all datasets providing HRQOL data (n = 263) were included in this predefined subanalysis. Stronger improvements in the physical component summary (PCS) were observed in the intervention compared to the control group, peaking after 3 months (estimated treatment difference 2.7 [1.2; 4.2]; p < 0.0001), but also in the long-term. Multiple regression analysis demonstrated that insulin levels and the achieved weight loss were associated with the mental component summary (MCS) after 12 months (p < 0.05). Thus, meal replacement-based lifestyle intervention is not only effective in weight reduction but, concomitantly, in enhancing HRQOL.

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Section: Introductionmentioning

confidence: 99%

High-Protein, Low-Glycaemic Meal Replacement Improves Physical Health-Related Quality of Life in High-Risk Persons for Metabolic Syndrome—A Subanalysis of the Randomised-Controlled ACOORH Trial

Kempf¹,

Röhling²,

Banzer

et al. 2022

Nutrients

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“…A minority (9%) of the study population increased their level of adherence to the Mediterranean diet over time. This low percentage probably reflects the difficulty in improving and sustaining beneficial dietary changes in the adult population, which has been highlighted in numerous previous studies [ 59 , 60 , 61 , 62 ]. Participants in the low–high Mediterranean diet trajectory exhibited a higher baseline financial status compared to participants in the low–low Mediterranean diet trajectory.…”

Section: Discussionmentioning

confidence: 98%

Longitudinal Trends, Determinants, and Cardiometabolic Impact of Adherence to the Mediterranean Diet among Greek Adults

Georgoulis

Georgousopoulou

Chrysochoou

et al. 2022

Foods

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Despite the well-established health benefits of the Mediterranean diet, there are signs that Mediterranean populations are deviating from this traditional pattern. We aimed to evaluate longitudinal changes in adherence to the Mediterranean diet, its determinants and health effects in a representative sample of the adult Greek population. This was a secondary analysis of the ATTICA epidemiological cohort study conducted in 2001/2002 and 2011/2012. The study sample consisted of 3042 men and women free of cardiovascular diseases living in Attica, Greece; of them, 2583 were followed-up for 10 years. Participants were evaluated in terms of sociodemographic, lifestyle and clinical parameters at baseline, and incidence of cardiometabolic diseases was recorded at follow-up. Dietary habits were assessed both at baseline and 10 years through a validated food frequency questionnaire and adherence to the Mediterranean diet was evaluated through the MedDietScore, based on which four trajectories were identified, i.e., low–low, low–high, high–low and high–high. During the study period, 45.6% of participants moved away from the Mediterranean diet (high–low), 9.0% moved closer (low–high), while 18.7% sustained a high adherence (high–high). Participants in the high–high trajectory were younger, mostly women, more physically active, had a higher socioeconomic status, and a more favorable body composition and cardiometabolic profile at baseline, and exhibited lower 10-year incidence rates of hyperlipidemia, hypertension, diabetes mellitus and cardiovascular disease compared to other trajectories (all p-values < 0.050). Adherence to the Mediterranean diet is declining among Greek adults. Staying close to the Mediterranean diet is associated with significant health benefits and should be a major target of public health strategies.

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“…Further well-designed, long-term studies measuring gold standard neuropathy outcomes are needed to strengthen the evidence base, for which the results of the recently commenced ADAPT trial may provide important insights [ 75 ]. Additionally, cost–benefit analyses are needed for ongoing allied health professionals in order to promote the adoption, adherence and maintenance of lifestyle interventions, and to inform their suitability for routine clinical translation [ 76 ].…”

Section: Metabolic Peripheral Neuropathymentioning

confidence: 99%

Current and Emerging Pharmacotherapeutic Interventions for the Treatment of Peripheral Nerve Disorders

et al. 2022

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Peripheral nerve disorders are caused by a range of different aetiologies. The range of causes include metabolic conditions such as diabetes, obesity and chronic kidney disease. Diabetic neuropathy may be associated with severe weakness and the loss of sensation, leading to gangrene and amputation in advanced cases. Recent studies have indicated a high prevalence of neuropathy in patients with chronic kidney disease, also known as uraemic neuropathy. Immune-mediated neuropathies including Guillain-Barré syndrome and chronic inflammatory demyelinating polyradiculoneuropathy may cause significant physical disability. As survival rates continue to improve in cancer, the prevalence of treatment complications, such as chemotherapy-induced peripheral neuropathy, has also increased in treated patients and survivors. Notably, peripheral neuropathy associated with these conditions may be chronic and long-lasting, drastically affecting the quality of life of affected individuals, and leading to a large socioeconomic burden. This review article explores some of the major emerging clinical and experimental therapeutic agents that have been investigated for the treatment of peripheral neuropathy due to metabolic, toxic and immune aetiologies.

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Facilitators and barriers for lifestyle change in people with prediabetes: a meta-synthesis of qualitative studies

Cited by 46 publications

References 76 publications

High-Protein, Low-Glycaemic Meal Replacement Improves Physical Health-Related Quality of Life in High-Risk Persons for Metabolic Syndrome—A Subanalysis of the Randomised-Controlled ACOORH Trial

High-Protein, Low-Glycaemic Meal Replacement Improves Physical Health-Related Quality of Life in High-Risk Persons for Metabolic Syndrome—A Subanalysis of the Randomised-Controlled ACOORH Trial

Longitudinal Trends, Determinants, and Cardiometabolic Impact of Adherence to the Mediterranean Diet among Greek Adults

Current and Emerging Pharmacotherapeutic Interventions for the Treatment of Peripheral Nerve Disorders

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