2024
DOI: 10.3390/jcdd11070186
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Facilitators and Barriers of Incremental Innovation by Fixed Dose Combinations in Cardiovascular Diseases

András Inotai,
Zoltán Kaló,
Zsuzsanna Petykó
et al.

Abstract: Despite the availability of affordable pharmaceuticals treating cardiovascular diseases (CVDs), many of the risk factors remain poorly controlled. Fixed-dose combinations (FDCs), a form of incremental innovation, have already demonstrated improvements over combinations of single medicines in adherence and hard clinical endpoints. Nevertheless, there are many barriers related to the wider use of FDCs in CVDs. Our aim was to identify these barriers and explore system-level facilitators from a multi-stakeholder p… Show more

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