AimThe present study aimed to explain the barriers to effective clinical supervision from the perspective of nurses.DesignQualitative descriptive study.MethodsThe present study enrolled 21 nurses selected by purposive sampling. Data were collected through semi‐structured interviews, which were digitally recorded and immediately transcribed verbatim, and analysed using content analysis method.ResultsFrom the nurses' perspective, the influential barriers included poor academic, ethical, communicational, professional competencies at the passive management level, defects in supervision prerequisites, conventional beliefs, ineffective organization, shortage of workforce at the level of inappropriate context, lack of motivation and poor accountability at inadequate professional maturity level.Public ContributionThe following items affect how clinical supervision is implemented: Motivation, accountability at the personal level, sufficient workforce, conducive conditions, effective organization of resources, and preparing the individual for supervision at the organizational level to implement effective clinical supervision.