Fact or Fiction—Is Abuse Prevalent in Patients With Interstitial Cystitis? Results From a Community Survey and Clinic Population

Peters, Kenneth M.; Kalinowski, Scott E.; Carrico, Donna J.; Ibrahim, Ibrahim A.; Diokno, Ananias C.

doi:10.1016/j.juro.2007.05.047

Cited by 56 publications

(41 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…When the McGill pain descriptors were evaluated separately, the sensory component of pain was more predominant in the IC/BPS patients reporting sexual abuse compared to those without, perhaps adding some credibility to the other arguments regarding possible associated mechanisms. 2,3 Similar to the weak association with depression and physical quality of life, these relationships with sexual abuse became nonsignificant when appropriate statistical adjustments were performed for multiple tests. We further noted that there appeared to be a similar weak impact of childhood sexual abuse on depression, anxiety, stress, mental quality of life, social interaction in the non IC/BPS control group; again, when the appropriate statistics were applied, these apparent associations were not statistically significant.…”

Section: Discussionmentioning

confidence: 88%

“…25 Peters and colleagues documented that 17.7% of IC/BPS patients versus 8.2% of control subjects reported a history of sexual abuse. 2 Clemens and colleagues 26 found that women with IC in a population-based study were 9 times more likely to have a diagnostic code for child abuse (which includes sexual abuse, but also physical and emotional abuse) than agematched controls. In their selected cohort of women with IC/BPS, Seth and colleagues found that 25% of women who reported a history of sexual abuse appeared to have a different clinical presentation than those with no reported abuse history.…”

Section: Discussionmentioning

confidence: 99%

“…3 Patients with IC/BPS and a history of sexual abuse had less frequency, nocturia, larger voided volumes, more tender areas on physical examination and worse domain scores on FSFI compared to those IC/BPS patients without a history of abuse. Both Peters and colleagues 2 and Seth and colleauges 3 have hypothesized that the physical trauma associated with early abuse may increase the likelihood of pelvic pain through neurogenic inflammation, as well as central sensitization.…”

Section: Discussionmentioning

confidence: 99%

“…1 It has been documented that patients diagnosed with IC/BPS have a higher prevalence of reported sexual abuse than women without IC/BPS 2 and that the presenting symptoms of IC/ BPS patients reporting abuse are different than those without a history of abuse. 3 This literature would suggest that this could be an important observation to expand our understanding of this enigmatic urologic chronic pelvic pain syndrome.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Childhood sexual trauma in women with interstitial cystitis/bladder pain syndrome: a case control study

Nickel

Tripp

Pontari

et al. 2013

CUAJ

View full text Add to dashboard Cite

Background: The impact of early lifetime trauma on symptom severity and quality of life of patients with interstitial cystitis/bladder pain syndrome (IC/BPS) has not been fully elucidated. We wanted to determine and compare the prevalence and impact of childhood traumatic events, with an emphasis on childhood sexual abuse, on patient symptoms, quality of life and other biopsychosocial parameters. Methods: Subjects (female patients with IC/BPS and controls without IC/BPS) completed psychosocial phenotyping questionnaires, including a demographics/history form, and validated questionnaires focused on presenting symptoms (IC symptom indices, pain), psychosocial parameters (depression, anxiety, pain catastrophizing, sexual functioning, social support) and quality of life. Participants also completed the Childhood Traumatic Events Scale. Results: Questionnaires were completed by 207 IC/BPS patients and 117 controls matched for age, partner status and education. It was found that before 17 years of age, the IC/BPS cases reported higher prevalence of "raped or molested" compared to controls (24.0% vs. 14.7%; p = 0.047). Within the IC/BPS group, cases reporting previous sexual abuse endorsed greater sensory pain, depression and poorer physical quality of life at the present time compared to IC cases without a sexual abuse history. In the controls only, those reporting previous sexual abuse endorsed more depression, anxiety, stress, social maladjustment poorer mental quality of life in the present time. When the analysis was corrected for potential multiple comparison error, none of the findings remained significant in either the IC/BPS or control groups. Interpretation: Childhood traumatic events, in particular sexual abuse and extreme illness, are reported as more common in IC/ BPS patients than controls. Early trauma, such as the occurrence of sexual abuse, is associated with some differences in patient adjustment (e.g., pain, quality of life, depression) but this impact appears to be, at most, very modest.

show abstract

Section: Discussionmentioning

confidence: 88%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Childhood sexual trauma in women with interstitial cystitis/bladder pain syndrome: a case control study

Nickel

Tripp

Pontari

et al. 2013

CUAJ

View full text Add to dashboard Cite

show abstract

“…31 Several studies have reported an association between IC and sexual, physical, and emotional abuse. 32 Familial occurrence of PBS is suggested by a study that found that adult female first-degree relatives of patients with IC may have a prevalence of IC 17 times that found in the general population. A greater concordance of IC among monozygotic than dizygotic twins also has been described.…”

Section: Risk Assessmentmentioning

confidence: 99%

Urologic Chronic Pelvic Pain Syndrome

Martínez-Bianchi

Halstater

2010

Primary Care: Clinics in Office Practice

View full text Add to dashboard Cite

The association between exposure to domestic abuse in women and the development of syndromes indicating central nervous system sensitization: A retrospective cohort study using UK primary care records

Chandan

Keerthy

Gokhale

et al. 2021

European Journal of Pain

View full text Add to dashboard Cite

Background Domestic abuse is a global public health issue. The association between the development of central sensitivity syndromes (CSS) and previous exposure to domestic abuse has been poorly understood particularly within European populations. Methods A retrospective cohort study using the ‘The Health Improvement Network,’ (UK primary care medical records) between 1st January 1995–31st December 2018. 22,604 adult women exposed to domestic abuse were age matched to 44,671 unexposed women. The average age at cohort entry was 36 years and the median follow‐up was 2.5 years. The outcomes of interest were the development of a variety of syndromes which demonstrate central nervous system sensitization. Fibromyalgia, chronic fatigue syndrome and temporomandibular joint disorder outcomes have been reported previously. Outcomes were adjusted for the presence of mental ill health. Results During the study period, women exposed to domestic abuse experienced an increased risk of developing chronic lower back pain (adjusted incidence rate ratio [aIRR] 2.28; 95% CI 1.85–2.80), chronic headaches (aIRR 3.15; 95% CI 1.07–9.23), irritable bowel syndrome (aIRR 1.41; 95% CI 1.25–1.60) and restless legs syndrome (aIRR 1.89; 95% CI 1.44–2.48). However, no positive association was seen with the development of interstitial cystitis (aIRR 0.52; 95% CI 0.14–1.93), vulvodynia (aIRR 0.42; 95% CI 0.14–1.25) and myofascial pain syndrome (aIRR 1.01; 95% CI 0.28–3.61). Conclusion This study demonstrates the need to consider a past history of domestic abuse in patients presenting with CSS; and also consider preventative approaches in mitigating the risk of developing CSS following exposure to domestic abuse. Significance Domestic abuse is a global public health issue, with a poorly understood relationship with the development of complex pain syndromes. Using a large UK primary care database, we were able to conduct the first global cohort study to explore this further. We found a strong pain morbidity burden associated with domestic abuse, suggesting the need for urgent public health intervention to not only prevent domestic abuse but also the associated negative pain consequences.

show abstract

Fact or Fiction—Is Abuse Prevalent in Patients With Interstitial Cystitis? Results From a Community Survey and Clinic Population

Cited by 56 publications

References 15 publications

Childhood sexual trauma in women with interstitial cystitis/bladder pain syndrome: a case control study

Childhood sexual trauma in women with interstitial cystitis/bladder pain syndrome: a case control study

Urologic Chronic Pelvic Pain Syndrome

The association between exposure to domestic abuse in women and the development of syndromes indicating central nervous system sensitization: A retrospective cohort study using UK primary care records

Contact Info

Product

Resources

About