Factores determinantes de la elevación de la uremia en los primeros días de vida en recién nacidos con menos de 30 semanas de gestación

Lozano, G. Bustos; Gallardo, C. Orbea; Miguel, S. Fernández de; Labián, M.aC. Muñoz; Maestro, María López; Pumarega, M Moral

doi:10.1016/s1695-4033(03)78780-3

Cited by 1 publication

(1 citation statement)

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“…Neither high chloride levels nor low SID were associated to impaired neurological outcome (severe abnormal cerebral ultrasound or cerebral palsy). It is worthy to note that the incidence of hypernatraemia was very low in our study, especially when compared to previous reports [22, 23]. …”

Section: Resultscontrasting

confidence: 52%

Chloride Balance in Preterm Infants during the First Week of Life

Iacobelli

Kermorvant‐Duchemin

Bonsante

et al. 2012

International Journal of Pediatrics

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Objective. To describe the chloride balance in infants born 25–32-week gestation, analyze the association of chloride changes with hydroelectrolytic status and their relationship with perinatal conditions, morbidities, and neurological outcome. Methods. For 7 days after birth, sodium and chloride balance, plasma potassium, phosphate, and total carbon dioxide (tCO2) were prospectively determined and strong ion difference (SID) calculated. Three multivariate regression analyses were performed to identify factors associated with high plasma chloride concentration, low SID, and low tCO2. Results. 107 infants were studied. Plasma chloride concentration was significantly positively associated with plasma sodium concentration. Higher plasma chloride and lower SID were significantly associated with lower plasma tCO2. Chloride intake was the main independent factor associated with high plasma chloride, low SID, and low plasma tCO2, with lesser contribution of sodium intake and low gestational age (GA). Also, patent ductus arteriosus and birth weight loss were independent factors affecting plasma chloride and SID. Neither high chloride levels nor low SID were associated to impaired neurological outcome. Conclusions. In preterm infants, chloride balance is influenced by GA and by interrelationship between sodium and chloride intake. High chloride levels are associated with metabolic acidosis but not related to increased risk of impaired neurological outcome.

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Section: Resultscontrasting

confidence: 52%