Factors Affecting Food Allergy-Related Quality of Life From Parents' Perception in Turkish Children

Abstract

PurposeFood allergy (FA) affects the daily lives of children and parents in varying degrees. The Food Allergy Quality of Life Questionnaire-Parent Form (FAQLQ-PF) is a valid and reliable instrument to assess the quality of life (QoL) of children from parents' perception. The aim of this study was to validate and determine the reliability of the Turkish FAQLQ-PF and to assess QoL in food-allergic children.MethodsChildren aged between 0 and 12 years and diagnosed with immunoglobulin E (IgE)-mediated FA for at least 1 month were enrolled. The English FAQLQ-PF was translated into Turkish according to the World Health Organization guidelines. The Food Allergy Independent Measure and the Turkish Child Health Questionnaire-Parent Form 50 were used for construct validity.ResultsOne hundred and fifty-seven patients participated. The median age of patients and FA duration were 2.4 years (1.2–5.2 years, interquartile-ranges) and 2 years (0.8–5.1), respectively. Ninety-six (61.1%) patients had anaphylaxis. The Cronbach's alpha coefficient and intra-class correlation coefficient for test-retest reliability was good for all age groups of children (<4, 4–6, and 7–12 years). Patients with either asthma or anaphylaxis had worse scores than others. Total scores of FAQLQ-PF tended to increase with age. Patients aged 7–12 had the highest total scores among all patients (2.2±0.1, 3.0±0.2, and 3.3±0.3 for <4, 4–6, and 7–12 years, respectively, P<0.001, P for trend <0.001). Other factors causing the poor QoL were cow's milk allergy, sibling allergy, mother's age over 30 years, mother's high education level and lower number of persons in household.ConclusionsThe Turkish FAQLQ-PF is a valid and reliable scale. FA-related QoL was significantly worse with age. Coexistent asthma, anaphylaxis regardless of its severity, cow's milk allergy, sibling allergy and the older and educated mothers seem to poorly affect QoL.

High anxiety and health-related quality of life in families with children with food allergy during coronavirus disease 2019

“…Most children had been diagnosed by an allergist (15/24; 62.5%), had to avoid 1 to 2 foods (18/25; 72.0%), and nearly one-third (8/28; 28.6%) had a history of anaphylaxis. For mothers with children aged 0 to 1.5 years, the mean PASS score was 22.6 plus or minus 16 For mothers with children aged 1.5 to 8 years, the mean GAD-7 score was 7.2 plus or minus 6.0, with 33.8% of mothers reporting clinical anxiety (score of !10). Statistically significantly greater raw GAD-7 scores were found in cases (n ¼ 18; mean, 10.33 [95% CI, 6.23-7.74]) than controls (n ¼ 233; mean, 6.99 [95% CI, 6.23-7.74; P < .02]) (Table 3).…”

“…Previous studies on food allergy have used a variety of anxiety and QoL tools 10 , 11 , 12 , 13 , 14 and used in diverse populations. 2 , 15 , 16 , 17 , 18 , 19 …”

“…8 Previous studies on food allergy have used a variety of anxiety and QoL tools [9][10][11][12][13] in diverse populations. 2,[14][15][16][17][18] We previously reported that the prevalence of depressive and anxiety symptoms among mothers of children aged 0 to 8 years is high during the COVID-19 pandemic. 19 To the best of our knowledge, there are no previous reports of maternal anxiety and HRQL, with consideration to food allergy, during the current pandemic.…”

Adaptation, Translation and Validation of the Food Allergy Quality of Life Questionnaire-Parent Form (FAQLQ-PF): The Malay Version

“…Previous literature reported that food allergies are prevalent in this age group; thus, it is important to measure their QoL [6,8]. The FAQLQ-PF is widely utilized worldwide and has been adapted and translated into nine languages, including Spanish, Turkish, Swedish, Japanese, Portuguese, Dutch, French and Ukrainian [23][24][25][26][27][28][29][30]. It is a valid and reliable tool to assess the QoL of children with food allergies by using parents as a proxy to answer the questionnaire [22].…”

Living with Food Hypersensitivity as an Adolescent Impairs Health Related Quality of Life Irrespective of Disease Severity: Results from a Population-Based Birth Cohort

“…Previous reports from our group and from others provide further evidence that children and adolescents with FHS have low HRQoL [ 25 , 26 , 27 , 28 , 29 ]. Children with more severe FHS, asthma comorbidity or experienced anaphylaxis have lower quality of life than those with less severe disease [ 30 , 31 , 32 ]. Among younger adolescents (ages 12–13 years), different phenotypes of FHS were shown to have no further impact on HRQoL, but tended to impact on those with a current food allergy [ 33 ].…”