Factors Affecting Frailty Syndrome in Elderly Chronic Obstructive Pulmonary Disease Patients and Its Relationship With Systemic Inflammation

Prevalence and risk factors of frailty in patients with chronic obstructive pulmonary disease: systematic review and meta-analysis

“…A total of seven studies [ 17 , 23 , 24 , 30 , 31 , 33 , 35 ] investigated the relationship between the COPD CAT score and the risk of frailty in patients with COPD; however, most were unsuitable for extracting data and the meta-analysis could only be performed in terms of two of these studies [ 24 , 33 ]. The results suggested that the CAT score was an indicator for frailty in patients with COPD (OR = 1.19; 95% CI = 1.12–1.27) (Supplemental File 4).…”

Frailty and its Influence on Mortality and Morbidity in COPD: A Systematic Review and Meta-Analysis

“…1). Eleven studies were determined as good quality [23][24][25][26][27][28][29][30][31][32][33], fourteen were categorised as fair quality [34][35][36][37][38][39][40][41][42][43][44][45][46][47]. For further details of the quality assessments tool, see SI-Table 1A, SI-Table 1B, and SI-Table 1C.…”

“…There was a range of frailty assessment tools used in the included studies, of which 22 were deemed suitable for inclusion in the frailty prevalence estimation. The average age of the participants was 70 years old; this does not include the study by Mustafaoğlu et al [47] as the mean age was not recorded, although the study reported age range 65-84 (Table 1).…”

“…The included studies were published between 2018 and 2022, and of the 25 studies, 11 were cohort studies and 14 were cross-sectional (Table 1). The studies originated from Japan [34][35][36]40], Taiwan [41], China [28,45], Singapore [32], Turkey [47], Greece [33], Italy [26,43,46], Spain [38,39], the United Kingdom [24,30], the Netherlands [42], Brazil [23], USA [25,29,31], and Canada [27,44]. Of the 25 studies, 5882 participants were included, 46.5% were male (2735/5882).…”

Determinants of Frailty and Gait Speed in People Over 65 Years of Age

“…Frailty is a dynamic condition resulting in the individual experiencing losses in one or more areas (physical, psychological, and social) of human function. Frailty manifests with aging and is affected by various stressful situations (1,2). In recent years, the importance of the concept of frailty has increased in studies related to old age and clinical care of the elderly (3).…”