Factors affecting health-related quality of life in women with recurrent breast cancer in Korea

Lee, Myung Kyung; Son, Byung Ho; Hwang, Sook Yeon; Han, Wonshik; Yang, Jung Hyun; Lee, Seeyoun; Yun, Young Ho

doi:10.1007/s11136-006-9144-6

Cited by 20 publications

(42 citation statements)

References 40 publications

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“…Firstly, univariate analyses were performed for socio-demographic characteristics including age at first diagnosis, age at recurrence, marital status, education, job, economic status and clinical variables including menstruation, time since first diagnosis, time since recurrence, performance status, chemotherapy, and recurrence pattern (data not shown). We only included variables in the multiple regression models which were determined as significant according to univariate analysis or were reported as strong predictors for QOL of recurrent breast cancer patients in previous studies [2,8,16-18]. Therefore, age at recurrence, education, financial status and marital status among the socio-demographic characteristics were entered in the first block, and time since recurrence, performance status and recurrence pattern among clinical variables were entered in the second block.…”

Section: Resultsmentioning

confidence: 99%

“…A few factors have been identified as predictors of overall quality of life among women with recurrent breast cancer, including age, time since recurrence, recurrence pattern (local-regional or distant recurrence), sites of metastasis, current physical symptoms, and treatment status [16-18]. Unmet needs were reported to be associated with QOL in breast cancer patients [13,15,19,20].…”

Section: Introductionmentioning

confidence: 99%

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Unmet Needs and Their Relationship with Quality of Life among Women with Recurrent Breast Cancer

Park

Hwang

2012

J Breast Cancer

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PurposeThis study aimed to evaluate the prevalence and the effects of unmet needs on quality of life (QOL) among recurrent breast cancer survivors.MethodsCompleted questionnaires were collected from 52 women with recurrent breast cancer. Clinical and socio-demographic characteristics were reviewed, and the Supportive Care Needs Survey, Functional Assessment of Cancer Therapy-Breast Cancer Instrument, and Beck Depression Inventory (BDI) were administered. The frequency of unmet needs and the mean differences by patient characteristics and BDI scores were analyzed. The predictive value of unmet needs on QOL, controlling for socio-demographic variables and then for clinical variables, was analyzed in hierarchical regression models.ResultsThe most common unmet needs belonged to the health system and information domain. The depressive group had greater unmet needs in the psychological domain (p<0.001), physical and daily living domain (p=0.001), and health and information domain (p=0.002). Patients with lower education attainment and those with lower performance status had greater unmet needs in the psychological needs (p=0.002) and in the physical and daily living needs domain (p=0.002), respectively. Unmet needs in the psychological domain (p=0.008), physical and daily living domain (p=0.022), and sexuality domain (p=0.040) strongly predicted QOL of women with recurrent breast cancer.ConclusionUnmet needs were strong predictors for QOL among recurrent breast cancer patients. This suggests that QOL of women with recurrent breast cancer is possibly more affected by unmet needs than by patient's socio-demographic or clinical characteristics. Intervention strategies could be developed based on the identified needs of women with recurrent breast cancer in order to improve their QOL. Further longitudinal and prospective studies will be necessary to confirm the independent impact of unmet needs on QOL.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Unmet Needs and Their Relationship with Quality of Life among Women with Recurrent Breast Cancer

Park

Hwang

2012

J Breast Cancer

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“…Little documentation exists about the multiple and cumulative effects of treatment drugs on symptoms related to urogenital atrophy with breast cancer recurrence (Lee et al, 2007;Oh et al, 2004). Andersen, Carpenter, Yang, and Shapiro (2007) studied sexual well-being among partnered breast cancer survivors with recurrent disease by comparing women free of disease (n = 120) to women experiencing a breast cancer recurrence (n = 73).…”

Section: Urogenital Atrophy In Breast Cancer Recurrencementioning

confidence: 99%

Urogenital Atrophy in Breast Cancer Survivors

Lester¹,

Bernhard²

2009

Oncology Nursing Forum

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Nurses must listen with sensitivity to breast cancer survivors and their descriptions of these significant and life-altering symptoms. Personalized discussion enables the nurse to explore issues, assess symptoms, recommend interventions, and evaluate at follow-up visits. Nurses are integral to the provision of survivorship care planning that can address the short- and long-term effects of a cancer diagnosis and related treatments.

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“…The Korean version of this combined questionnaire has been validated [34,35]. Also, EORTC QLQ-C30 and QLQ-BR23 have earlier been used successfully in many studies to compare BCS with the general population [12,[36][37][38][39][40][41]. Population-based data can be used to identify subgroups at increased risk of poor HRQOL and affective disorders, and to develop ways to facilitate rehabilitation.…”

Section: Control Group Participants and Data Collectionmentioning

confidence: 99%

Correlates of existential well-being and their association with health-related quality of life in breast cancer survivors compared with the general population

Shin

Noh

Lee

et al. 2009

Breast Cancer Res Treat

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The aim was to evaluate the correlates of existential well-being (EWB) and investigate the relationship between EWB and health-related quality of life (HRQOL) according to the McGill Quality of Life Questionnaire (MQOL) in breast cancer survivors (BCS) and in the general population. BCS (N = 1,933) recruited from five large hospitals completed a mailed survey, which included the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (QLQ-C30), Quality of Life Questionnaire Breast Cancer Module (QLQ-BR23) and the MQOL. Reference data were derived from a representative sample of the Korean adult population composed of 500 women selected by a nationwide random route technique. Multiple logistic regression analysis showed that members of the general population with a lower educational status were more likely to report poor EWB. However, among BCS, correlates that were associated with poor EWB included lower monthly income, lower educational status, unemployment and comorbidities. Almost all factors listed on the HRQOL questionnaire were correlated with EWB in BCS as well as in the general population (P < 0.001). Factors listed on the QLQ-C30 that were correlated to a clinically meaningful extent with EWB in the general population included physical functioning, nausea and vomiting, and appetite loss, whereas among BCS, insomnia and distress over hair loss were meaningfully correlated with EWB. Compared with general population, BCS showed different EWB correlates and distinct associations with HRQOL findings. Our data suggest that socio-economic status and comorbidities influence on their EWB.

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Factors affecting health-related quality of life in women with recurrent breast cancer in Korea

Abstract: Treatment completed, most degraded aspects of HRQOL in recurrent breast cancer women can return to levels observed in disease-free survivors.

Cited by 20 publications

References 40 publications

Unmet Needs and Their Relationship with Quality of Life among Women with Recurrent Breast Cancer

Unmet Needs and Their Relationship with Quality of Life among Women with Recurrent Breast Cancer

Urogenital Atrophy in Breast Cancer Survivors

Correlates of existential well-being and their association with health-related quality of life in breast cancer survivors compared with the general population

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