Factors Affecting Medication Adherence Among Adults with Schizophrenia: A Literature Review

Tham, Xiang Cong; Xie, Huiting; Chng, Cecilia Mui Lee; Seah, Xin Yi; Lopez, Violeta; Klainin‐Yobas, Piyanee

doi:10.1016/j.apnu.2016.07.007

Cited by 33 publications

(35 citation statements)

References 58 publications

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“…17 Therefore, the repercussions affect not only the individuals, but also the society. 18 Previous studies indicated that medication adherence with SMD was associated with various factors, such as patient-related, medication-related, illness-related, and external/environment factors. 18,19 Specifically including age, 20 insight, 21 education status, 22 the number of medications, 23 side effects of medications, 24 psychotic symptoms, social support 25 and therapeutic alliance.…”

Section: Introductionmentioning

confidence: 99%

<p>Factors Associated with Medication Adherence Among Patients with Severe Mental Disorders in China: A Propensity Score Matching Study</p>

Dou¹,

Hu²,

Zhang³

et al. 2020

PPA

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Objective The 686 project provides free essential drugs and follow-up for poor SMD patients, with the purpose of improving patients’ medication adherence and reducing the occurrence of dangerous behaviors. The objective of this research was to determine the factors that influence medication adherence in patients with severe mental disorders (SMD) and analyze whether the 686 program significantly improved patient medication adherence. Methods This study was conducted among SMD patients in 686 project and non-project SMD patients in the same community in 11 cities in Shandong Province of China. The data collected included basic patient information and disease treatment information. Medication adherence was divided into good adherence and poor adherence. Propensity score matching (1:1 match) was performed to adjust for differences in baseline characteristics. Results One thousand two hundred ninety-two patients receiving free medication assistance policy (686 project group) and 1292 non-policy patients (control group) were analyzed. Patients who received the 686 project group had significantly better medication adherence than the non-policy group patients (92.6% vs.61.2%). Older age and consolidation period were associated with poor adherence, and education level was the positive determinant for adherence. Conclusion The 686 project could improve medication adherence to patients with SMD. Additional research will pay attention to medication adherence of patients who are elderly, in consolidation period and lower education levels. It should strengthen the guidance and supervision of patients’ medication and strengthen the health education of family members and patients.

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Section: Introductionmentioning

confidence: 99%

<p>Factors Associated with Medication Adherence Among Patients with Severe Mental Disorders in China: A Propensity Score Matching Study</p>

Dou¹,

Hu²,

Zhang³

et al. 2020

PPA

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“…Our data showed that age, sex, and education had no significant effect on the risk of psychiatric rehospitalization. The above factors also showed an inconclusive effect on drug adherence [22]. Since we found no significant difference in the risk of psychiatric rehospitalization between the oral and LAI groups, we assumed the patients in the oral group had a fair drug adherence.…”

Section: Discussionmentioning

confidence: 88%

Differences in the Effectiveness of Long-Acting Injection and Orally Administered Antipsychotics in Reducing Rehospitalization among Patients with Schizophrenia Receiving Home Care Services

Hsu

Kao

et al. 2019

JCM

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The current study explored the differences in the effectiveness of first and second generation long-acting injections and orally administered antipsychotics in reducing the rehospitalization rate among patients with schizophrenia receiving home care services in a medical center in Southern Taiwan. Longitudinal data between 1 January 2006, and 31 December 2015, were collected retrospectively. Patients were classified into three treatment groups: First generation antipsychotic (FGA) long-acting injection (LAI), second generation antipsychotic long-acting injection (SGA) (LAI), and oral antipsychotics. The primary outcomes were the rehospitalization rate and the follow-up time (duration of receiving home care services) until psychiatric rehospitalization. A total of 78 patients with schizophrenia were recruited. The average observation time was about 40 months. The oral treatment group tended to be older with a higher number of female patients and a lower level of education. The FGA treatment group tended to have a higher frequency and duration of hospitalization before receiving home care services. We found no significant differences in the follow-up time or psychiatric rehospitalization rate after receiving home care services among the three treatment groups. We propose that oral and LAI antipsychotics were equally effective when patients received home care services. Our results can serve as a reference for the choice of treatment for patients with schizophrenia in a home care program.

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“…An extensive literature debating insight founded on patients with schizophrenia (SZD) or Bipolar Disorders (BD) studies exist (for review see: Tham et al., 2016; García et al., 2016; Murri et al., 2015; Leclerc et al., 2013, Velligan et al., 2017). In SZD, articles show links between insight and symptomatology such as for mood disorder (da Silva et al., 2016).…”

Section: Introductionmentioning

confidence: 99%

Impulsivity issues in borderline personality disorder and it's links with insight: the role of urgency

Martin

Del-Monte

Graziani

2019

Heliyon

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Impulsivity plays a major role in a wide range of disorders including Borderline Personality Disorder. Another crucial clinical dimension is insight. This clinical dimension is linked with symptomatology and treatment issue. The present study aims to investigate the impact of positive and negative urgency on insight in Borderline Personality Disorder. Methods: We recruited eighty-one women with Borderline Personality Disorder and assessed insight level and impulsivity scores using the Beck Cognitive insight scale and the UPPS-short form scale. Results: Our results showed interesting links between positive urgency and insight quality. Conclusion: Negative emotions play a fundamental role for the insight quality, but positive emotions are surprisingly related to clinical insight. We discuss the possible therapeutical impact of this results on treatment adaptation.

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Factors Affecting Medication Adherence Among Adults with Schizophrenia: A Literature Review

Cited by 33 publications

References 58 publications

<p>Factors Associated with Medication Adherence Among Patients with Severe Mental Disorders in China: A Propensity Score Matching Study</p>

<p>Factors Associated with Medication Adherence Among Patients with Severe Mental Disorders in China: A Propensity Score Matching Study</p>

Differences in the Effectiveness of Long-Acting Injection and Orally Administered Antipsychotics in Reducing Rehospitalization among Patients with Schizophrenia Receiving Home Care Services

Impulsivity issues in borderline personality disorder and it's links with insight: the role of urgency

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