Factors affecting outcomes of Yttrium-90 radioembolization in heavily pretreated patients with intrahepatic cholangiocarcinoma

Zhao, Ken; Erinjeri, Joseph P.; Sotirchos, Vlasios S.; Alexander, Erica S.; Moussa, Amgad M.; Marinelli, Brett; Ziv, Etay; Sofocleous, Constantinos T.; Abou‐Alfa, Ghassan K.; Jarnagin, William R.; Karimi, Anita; Yarmohammadi, Hooman

doi:10.1007/s00261-023-03930-0

Cited by 1 publication

(2 citation statements)

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“…Ongoing refinements focus on personalized dosimetry and improved patient selection to optimize treatment outcomes. 32,33 The integration of advanced imaging modalities, such as SPECT/CT and PET/CT, aids in precise microsphere delivery and post-treatment assessment, 34 contributing to the efficacy of radioembolization.…”

Section: Interventional Radiology Techniquesmentioning

confidence: 99%

“…Furthermore, locoregional therapies like trans-arterial embolization, chemoembolization, radio-embolization, and ablation have been associated with signalling pathways and gene expression patterns, suggesting potential correlations with treatment response. 32 Radiogenomics, focusing on imaging features and gene expression, holds promise for identifying prognostic or predictive biomarkers to guide treatment selection. 55 Radiogenomics in hepatocellular carcinoma has shown promise in identifying gene patterns related to aggressive imaging features and in predicting microscopic vascular invasion on pathology.…”

Section: Personalized Medicine In Interventional Oncologymentioning

confidence: 99%

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Interventional Oncology: 2024 Update

Geevarghese,

Bodard,

Razakamanantsoa

et al. 2024

Can Assoc Radiol J

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Interventional Oncology (IO) stands at the forefront of transformative cancer care, leveraging advanced imaging technologies and innovative interventions. This narrative review explores recent developments within IO, highlighting its potential impact facilitated by artificial intelligence (AI), personalized medicine and imaging innovations. The integration of AI in IO holds promise for accelerating tumour detection and characterization, guiding treatment strategies and refining predictive models. Imaging modalities, including functional MRI, PET and cone beam CT are reshaping imaging and precision. Navigation, fusion imaging, augmented reality and robotics have the potential to revolutionize procedural guidance and offer unparalleled accuracy. New developments are observed in embolization and ablative therapies. The pivotal role of genomics in treatment planning, targeted therapies and biomarkers for treatment response prediction underscore the personalization of IO. Quality of life assessment, minimizing side effects and long-term survivorship care emphasize patient-centred outcomes after IO treatment. The evolving landscape of IO training programs, simulation technologies and workforce competence ensures the field’s adaptability. Despite barriers to adoption, synergy between interventional radiologists’ proficiency and technological advancements hold promise in cancer care.

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Section: Interventional Radiology Techniquesmentioning

confidence: 99%

Section: Personalized Medicine In Interventional Oncologymentioning

confidence: 99%