Factors affecting spirometry reference range in growing children

Sadiq, Sara; Rizvi, Nadeem; Soleja, Fahad Khalid; Abbasi, Muaz

doi:10.12669/pjms.35.6.1212

Cited by 7 publications

(6 citation statements)

References 18 publications

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“…The correlations between spirometry parameters with height, weight, and age are well known. 30 However, they have been differently associated with predicted spirometry parameters. Higher weight coefficients for girls than boys have been reported in a few studies, 31 , 32 , 33 while others only account for height in both sexes.…”

Section: Discussionmentioning

confidence: 99%

Development and validation of predictive equations for spirometry in Portuguese children

Martins¹,

Severo²,

Silva³

et al. 2023

Journal of Allergy and Clinical Immunology: Global

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Section: Discussionmentioning

confidence: 99%

Development and validation of predictive equations for spirometry in Portuguese children

Martins¹,

Severo²,

Silva³

et al. 2023

Journal of Allergy and Clinical Immunology: Global

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“…This leads to a belief that differences in PEFR values between the genders occurs due to differences in airways and lung size, lung capacity, and the strength of respiratory muscles. The height, age, and weight in this study correlate w i t h t h e P E F R v a l u e s f o u n d i n o t h e r s t u d i e s (5)(6)(7)15,(23)(24)(25)(26)(27)(28)(29)(30)(31). Height is the highest correlation factor.…”

Section: Discussionmentioning

confidence: 58%

The reference values of peak expiratory flow rate in Thailand children

Srisingh

Phuaksaman

2021

J Thorac Dis

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Background: Daily evaluation of peak expiratory flow rate (PEFR) is quite useful for monitoring and adjusting an asthmatic patient's treatment. Many factors including geography, ethnicity, socio-economic conditions, gender, and anthropometric play a role in lung function differences studies have found. The aim of this study is to present normal PEFR and to establish a PEFR equation for Thai children living in a suburban environment. Methods: This study includes a cross-section of healthy children aged 6 to 18. It was conducted in Phitsanulok Province in the lower north of Thailand. The children were chosen to participate from five primary and secondary schools over the period from February 2014 to January 2015. The children were instructed on how to use the Wright peak flow meter (Clement Clarke International Ltd.). All of the participants performed PEFR 3 times and the highest value was recorded. Results: A total of 2,000 students were initially examined; 80 students were excluded from the study. A total of 1,920 healthy children were recruited between the ages of 6 and18 years. Among them, 719 (37.4%) were males and 1,201 (62.6%) were females. The median age was 18 [12][13][14][15][16][17][18] years old, mean height, weight, body mass index (BMI) and PEFR were 155.98±14.99 cm, 51.38±16.95 kg, 20.62±4.79 kg/m 2 and 339.31±113.55 L/min, respectively. PEFR has a linear relationship in regards age, weight, height and BMI. For males, age was the strongest factor associated with PEFR (r=0.838, P<0.001). Females had a highly significant correlation between height and PEFR (r=0.532, P<0.001). The regression equations are PEFR = (1.34 × height) + (1.41 × weight) + (16.56 × age) -137.88 for males (R 2 =0.751, P<0.001) and PEFR = (1.31 × height) + (0.94 × weight) + (7.30 × age) -55.27 for females (R 2 =0.507, P<0.001).Conclusions: This research study has provided the normal range of PEFR for Thai children aged from 6 to 18 years in Phitsanulok. The data was obtained using the Wright peak flow meter. Height, weight, and age were the significant determiners of the PEFR for each sex in the regression equation.

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“…7,8 Additionally, Age, and obesity influence lung function and intensified the harmful effects of air pollution on respiratory health. 2,9 The current study was conducted to highlight the impact of age, height, weight, and obesity on PEFR of inhabitants of chemical industries, who are exposed to chemicals and smoke on daily basis. Our study demonstrates a significant relationship between age and obesity and PEFR in workers in chemical industries.…”

Section: Discussionmentioning

confidence: 99%

Emerging Risk Factors for Impaired Lung Function in Chemical Industry Workers of Faisalabad

Jawed¹,

Altaf²,

Rehman³

et al. 2022

JRMC

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Objective: To determine the impact, obesity and age on the lung functions determined by PEFR of healthy workers of chemical industries. Methodology: This was a cross sectional study performed at private medical college of Faisalabad. Three days medical camp was arranged during 2nd to 4th September 2020 after taking approval from institutional ethical committee. All relevant information including age, residence and history about chemical exposure were recorded in a structured proforma. Obesity was determined on basis of BMI grading. BMI was calculated from estimated Height and weight PEFR of each participant was determined using Wright’s Peak flow meter. Data was analyzed by SPSS21. Results: Mean± SD age, height and weight of the studied population was 38.85 ± 12.1, 170.07 ±12.0 and 78.12 ±12.7. lowest PEFR value was found in subjects with age range 61 to 70 years as compred to youger subjects . The mean PEFR value were significantly different with respect to various age catagoeies with p value= 0.000 Highest mean PEFR values were found in taller subjects having height ≥ 180 cm and lowest values were found in subjects with height 150-159 cm, the difference in means was statisticaly significant with p value= 0.05. Morbid obese subjects showing comparatively lower PEFR values in morbid obese with significant p value =0.002. . PEFR was found to be negatively associated with age ( p- value= 0.000*) and BMI( p value =0.001*). Our results also showed weak positive association of PEFR with height, however this relation was not found to be statistically significant (p value= 0.081). Conclusion: Peak expiratory flow rate is negatively associated with increasing BMI and age, reflecting that elderly and obese subjects are more prone to have affected lung function due to exposure to chemicals

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Factors affecting spirometry reference range in growing children

Cited by 7 publications

References 18 publications

Development and validation of predictive equations for spirometry in Portuguese children

Development and validation of predictive equations for spirometry in Portuguese children

The reference values of peak expiratory flow rate in Thailand children

Emerging Risk Factors for Impaired Lung Function in Chemical Industry Workers of Faisalabad

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