Abstract-Six constructs were utilized in this study to explore the factors affecting MIS implementation in Jordanian public institutions and to investigate the impact of MIS implementation on organizational (operational) performance. They were human factors, organizational factors, technological factors, environmental factors, MIS implementation components and organizational performance. The required data were collected using a valid and reliable questionnaire developed based on the literature review. Human factors were conceptualized as users' computer skills and experience, IS usefulness and IS ease of use. Organizational factors were assessed using three sub-indicators, which were top-management support, user training and IS confidentiality. Technological factors were evaluated by systematic quality, information quality and service quality. The overall industry, industry environment and external pressure were three indicators used to measure the environmental factors. Two variables were selected to measure MIS implementation: IT/IS capability and technological aspects related to information service quality. Since the current study tackled public institutions, the indicators of organizational performance were limited to operational ones. The questionnaire was distributed to 125 informants from IT/IS departments. The findings of the study indicated the acceptance of the hypothesis that the factors in question are significantly and positively related to MIS implementation, which in turn, when measured by IT/IS capability and information service quality, significantly and positively affect organizational performance. The main contribution provided by this study is that MIS implementation is not limited to information technology and systems capabilities and usefulness. Other factors should be considered, particularly when examining the impact of MIS implementation on organizational performance.