Factors Affecting Therapeutic Compliance among the Patients with Rheumatic Heart Disease in Bangladesh

Farzana, Kakon; Faruque, Mohammad Omar; Zareen, Salma; Choudhury, Kamrun Nahar; Hossain, Ahmed

doi:10.3329/cardio.v10i2.36289

Cited by 5 publications

(7 citation statements)

References 7 publications

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“…Factors associated with adherence in the present study were: 1) heart condition of the patients (also supported by Sial et al 55 ); 2) residence (also in harmony with Gasse et al, 38 who reported that living rurally where there is no health-system coverage predisposes RHD patients to poor adherence to secondary prophylaxis); and 3) long distance from the health institution (also supported by a number of studies 34,39,41,48 ).…”

supporting

confidence: 84%

“…Otherwise, there is a higher risk of recurrent ARF and its complications. 29,30 However, ensuring adequate adherence to secondary prophylaxis has been a challenge, and the adherence rate is poor among adolescents and chronic patients, [31][32][33][34][35][36] due to different factors 34,[37][38][39][40][41][42] and barriers. [43][44][45][46][47][48] There are no reliable and consistent data in Ethiopia, asstudies have been conducted only at a single institution.…”

Section: Introductionmentioning

confidence: 99%

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Rheumatic Heart Disease Patients’ Adherence to Secondary Prophylaxis and Associated Factors at Hospitals in Jimma Zone, Southwest Ethiopia: A Multicenter Study

Adem¹,

Gemechu²,

Jarso³

et al. 2020

PPA

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Background: Rheumatic heart disease (RHD) is a major cause of preventable premature cardiovascular-related death in developing countries. However, information regarding adherence rates and associated factors is limited and inconsistent in Ethiopia. Methods: A cross-sectional study was conducted from August to November 2019 among selected RHD patients on follow-up at four hospitals in Jimma zone. Data were collected using a structured questionnaire. Adherence of RHD patients to secondary prophylaxis in the previous consecutive 12 months was assessed based on the annual frequency of received prophylaxis (monthly injection of benzathine penicillin). Good adherence was considered the patient receiving >80% of the annual dose. The collected data were entered into Epidata 3.1 and analysed using SPSS 23. Results: A total of 253 RHD patients taking prophylaxis were included in the analysis, and of those 178 (70.4%) were female, giving a male:female ratio of 1:2.4. The mean age was 24 ±11 (6-65) years. About 63% had good adherence to benzathine penicillin prophylaxis. New York Heart Association functional class I and II, rural residence, >30 km from health facility, and duration of prophylaxis >5 years were associated with poor adherence (respectively: AOR 12.6 [95% CI 2.5-63], P=0.

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supporting

confidence: 84%

Section: Introductionmentioning

confidence: 99%

Rheumatic Heart Disease Patients’ Adherence to Secondary Prophylaxis and Associated Factors at Hospitals in Jimma Zone, Southwest Ethiopia: A Multicenter Study

Adem¹,

Gemechu²,

Jarso³

et al. 2020

PPA

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“…In contrast to this, a study from Bangladesh reported that duration on BPG taking, age, sex, education and marital status were significantly associated with therapeutic compliance among the patients with RHD. 29 Furthermore, a study conducted at Fiji (South Pacific) also revealed that age and duration of taking BPG were associated with the status of adherence. 30 These differences might be due to the relatively small participants number and the difference in socio-demographic characteristics.…”

Section: Discussionmentioning

confidence: 99%

Adherence to Benzathine Penicillin G Secondary Prophylaxis and Its Determinants in Patients with Rheumatic Heart Disease at a Cardiac Center of an Ethiopian Tertiary Care Teaching Hospital

Mekonen

Yismaw

Abiye

et al. 2020

PPA

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Purpose: Benzathine penicillin G (BPG) monthly administration is the most effective method for secondary prophylaxis against acute rheumatic fever (ARF). BPG's efficacy largely depends on adherence to treatment. This study was aimed at assessing adherence to BPG prophylaxis and its determinants among adult patients with rheumatic heart disease. Patients and Methods: An institutional cross-sectional study design was used. One hundred and forty-five patients receiving monthly BPG at the Adult Cardiac Clinic of Tikur Anbessa Specialized Hospital (TASH) were interviewed. Their 1-year BPG prophylaxis administration record was also reviewed. The rate of adherence to BPG injection was determined by calculating the percentage of the administered drug from the total expected doses. Data were entered and analyzed using Statistical Package for Social Sciences (SPSS) software version 25. Both descriptive and logistic regression analyses were computed to describe different variables and assess factors associated with adherence, respectively. A p-value <0.05 was used to declare association. Results: Among a total of 145 study participants involved, the majority (76.6%) of them had been receiving BPG for the last 10 years. The average adherence rate to monthly BPG injection was 80.60% with a range of 0% to 100%. However, only 101 (69.7%) of participants were taking ≥80% of their prescribed monthly BPG prophylaxis doses. Study participants with informal education 1.10 (0.023-46.96) and secondary school education 0.89 (0.10-8.11) were more and less likely to adhere to BPG injection, respectively, when compared with those who attended higher education programs. The regression analysis showed patients who were not admitted to the hospital (AOR: 26.22; CI: 2.55-269.70; p=0.006) and once admitted patients (AOR: 50.08; CI: 2.87-873.77; p=0.007) were more likely to adhere to their BPG injections than those admitted twice or more. The study participants who waited until the next appointment were also less adherent (AOR: 0.02; CI: 0.00-0.13; p=0.000) than those who went a few days later for receiving the missed/late dose. Conclusion: The adherence rate to BPG injection among RHD patients was found to be high (80.60%). Patients' admission status and their action on missed and/or late doses were found to be important determinants of adherence in this study.

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“…A study in Bangladesh conducted during 2017 found 50% mean treatment adherence to medications among RF/RHD patients. [ 14 ] In our study, adherence rate to injection benzathine penicillin was calculated separately with a formula and found that 89.5% (17 of 19 participants) had an adherence rate above 80%. This compares well (92%)[ 15 ] with previous Indian studies and also Ethiopian study which had an overall adherence rate of 80.6%.…”

Section: Discussionmentioning

confidence: 81%

Treatment adherence and its determinants among the rheumatic fever/rheumatic heart disease patients during COVID 19 pandemic – A cross sectional study from Chandigarh, India

Ilanchoorian,

Thakur,

Vijayvergiya

et al. 2023

Journal of Family Medicine and Primary Care

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Background: Rheumatic heart disease/Rheumatic fever is a non – communicable disease being a major neglected health problem. Recurrent attacks of rheumatic fever can have catastrophic outcomes, therefore regular administration of antibiotics is recommended. During COVID 19 pandemic, people were afraid to approach hospitals hence the compliance and follow up of patients were affected. This study had planned to assess the treatment adherence of patients diagnosed with rheumatic fever/rheumatic heart disease during COVID 19 pandemic and to describe the socio demographic factors, clinical characteristics. This study also determines the factors associated with the treatment adherence. Methods: A cross sectional study was conducted among Rheumatic Fever/Rheumatic Heart Disease patients, attending Outpatient department at tertiary care hospital during COVID 19 pandemic. Mean score with confidence interval was calculated for quantitative data. P value less than 0.05 is significant. Results: The Mean (SD) age of the study participants was 41 ± 14.17 years. Treatment adherence was found to be 94.5 percent among Rheumatic Fever/Rheumatic Heart Disease patients during COVID 19 pandemic. 89.5% of injection benzathine penicillin users had an adherence rate above 80 percent. It was found that the presence of comorbidities (Diabetes/Hypertension/both Diabetes and Hypertension) had a statistically significant association with treatment adherence. Conclusions: Rheumatic Heart Disease is a disease of young and middle -age population affecting predominantly females. The overall adherence rate among Rheumatic Fever/Rheumatic Heart Disease patients was high. High time to maintain hospital-based registry to have follow up of patients.

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Factors Affecting Therapeutic Compliance among the Patients with Rheumatic Heart Disease in Bangladesh

Abstract: Abstract:Background: Acute rheumatic fever (ARF)

Cited by 5 publications

References 7 publications

<p>Rheumatic Heart Disease Patients’ Adherence to Secondary Prophylaxis and Associated Factors at Hospitals in Jimma Zone, Southwest Ethiopia: A Multicenter Study</p>

<p>Rheumatic Heart Disease Patients’ Adherence to Secondary Prophylaxis and Associated Factors at Hospitals in Jimma Zone, Southwest Ethiopia: A Multicenter Study</p>

<p>Adherence to Benzathine Penicillin G Secondary Prophylaxis and Its Determinants in Patients with Rheumatic Heart Disease at a Cardiac Center of an Ethiopian Tertiary Care Teaching Hospital</p>

Treatment adherence and its determinants among the rheumatic fever/rheumatic heart disease patients during COVID 19 pandemic – A cross sectional study from Chandigarh, India

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