Factors Associated With Achieving a Body Mass Index of Less Than 30 After Bariatric Surgery

Varban, Oliver A.; Cassidy, Ruth; Bonham, Aaron J.; Carlin, Arthur M.; Ghaferi, Amir A.; Finks, Jonathan F.

doi:10.1001/jamasurg.2017.2348

Cited by 44 publications

(29 citation statements)

References 35 publications

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“…The strong association between preoperative BMI and postoperative HRQoL are well in line with previous studies [10,13]. Although heavier patients (in particular younger patients) tend to lose more weight after bariatric surgery, they still have difficulties reaching a BMI < 30 [27].…”

Section: Discussionsupporting

confidence: 89%

The Influence of Socioeconomic Factors on Quality-of-Life After Laparoscopic Gastric Bypass Surgery

et al. 2019

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Introduction Patients with low socioeconomic status have been reported to experience poorer outcome after several types of surgery. The influence of socioeconomic factors on health-related quality-of-life (HRQoL) after bariatric surgery is unclear. Materials and Methods Patients operated with a primary laparoscopic gastric bypass procedure in Sweden between 2007 and 2015 were identified in the Scandinavian Obesity Surgery Register. Patients with a completed assessment of health-related quality-of-life based on the Obesity-related Problem Scale (OP Scale) were included in the study. Socioeconomic status was based on data from Statistics Sweden. Results A total of 13,723 patients (32% of the 43,096 operated during the same period), with complete OP scores at baseline and two years after surgery, were included in the study. Age, lower preoperative BMI, male gender, higher education, professional status and disposable income as well as not receiving social benefits (not including retirement pension), and not a first-or secondgeneration immigrant, were associated with a higher postoperative HRQoL. Patients aged 30-60 years, with lower BMI, higher socioeconomic status, women and those born in Sweden by Swedish parents experienced a higher degree of improvement in HRQoL. Postoperative weight-loss was associated with higher HRQoL (unadjusted B 16.3, 95%CI 14.72-17.93, p < 0.0001). Conclusion At 2 years, a strong association between weight loss and improvement in HRQoL was seen, though several factors influenced the degree of improvement. Age, sex, preoperative BMI and socioeconomic status all influence the postoperative HRQoL as well as the improvement in HRQoL after laparoscopic gastric bypass surgery.

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Section: Discussionsupporting

confidence: 89%

The Influence of Socioeconomic Factors on Quality-of-Life After Laparoscopic Gastric Bypass Surgery

et al. 2019

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“…Records of diabetic patients undergone bariatric surgery report decrease in the dose of insulin and oral antihyperglycemics used. Other additional benefits include reduced rates of hypertension, obstructive sleep apnea and improved lipid profile at 3-5 years post-surgery (Varban et al, 2017).…”

Section: Bariatric Surgerymentioning

confidence: 99%

Causes and solutions to “globesity”: The new fa(s)t alarming global epidemic

Vasileva

Marchev

Georgiev

2018

Food and Chemical Toxicology

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Diverse groups of factors are leading to increased weight gain and obesity, such as certain genetic phenotypes, neuroendocrine disturbances, the administration of some drugs, behavioral, social and environmental factors. The progressively escalating rates of overweight and obesity worldwide have led to an introduction of a new term "globesity". Excessive accumulation of body fat and especially of visceral adipose tissue is the main predisposing factor for the development of metabolic syndrome and other obesity related co-morbidities. At the present moment only few pharmacotherapeuticals are used for long-term treatment of obesity acting on narrow target spectra, e.g. pancreatic and gastric lipase inhibition, acting as adrenomimetics or activating the satiety centers in hypothalamus. Plant-based medications that accelerate weight loss, proved to be safe, effective and widely available, would be a preferable alternative for anti-obesity treatments. As plant extracts are multi-component systems they could also act by more than one mechanism, including decreased lipid absorption, decreased energy intake, increased energy expenditure, decreased pre-adipocyte differentiation and proliferation, decreased lipogenesis and increased lipolysis. The current review gives a summary of the risk factors for obesity development and its characteristics consequences. Current treatment options, combining lifestyle changes and conventional treatment with commercial anti-obesity drugs have been described as well. Special emphasis on in vitro, in vivo and human studies, of potential medicinal plant extracts and phytochemicals, such as polyphenols, terpenoids, alkaloids, saponins, able to modulate the molecular pathways and gene/protein expressions related to obesity, have been highlighted.

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“…Die folgende Frage "Wenn ja, welche Medikamentenverordnungen haben sich verändert?" wurde von 48 Pa- 32 (13,3) 66 (26,7) 30 (12,4) 43 (17,6) 59 (24,3) 37 15,36 2,54 1,74 1,78 3,316 6,749 (20,4) 28 (11,6) 11 4,718 7,5) 7 (2,94 1,722 (9,1) 25 (10,4) 62 (25,6) 20 (8,2) 18 (7,4) 25 (10,4) 15 ( Der statistische Vergleich der prä-und postoperativen Verordnungshäufigkeiten wurde mittels des exakten Fischer-Tests durchgeführt. ▶ Tabelle 4 zeigt eine Auswahl, Arzneimittel mit unveränderten Verordnungszahlen werden hier überwiegend nicht gezeigt.…”

Section: Discussionunclassified

“…Der Anteil der Patienten mit Hypertonie in dem vorliegenden Kollektiv fällt mit 62% größer aus als in Vergleichsstudien (45-60%). Da diese Studien allerdings jeweils mehrere Tausend Patienten eingeschlossen hatten (3,9,10), könnte in der Zusammensetzung unserer kleinen Stichprobe eine Verzerrung aufgetreten sein. Möglicherweise wird in Deutschland aber auch häufiger auf die Diagnose Hypertonie geachtet.…”

Section: Komorbiditäten In Der Gesamtstichprobeunclassified

Änderungen der Pharmakotherapie nach Adipositas-Chirurgie - eine monozentrische Erhebung

Hansen¹,

Mall²,

Engeli³

2018

Adipositas - Ursachen, Folgeerkrankungen, Therapie

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ZusammenfassungDie Arzneimitteltherapie des adipösen Patienten wird durch vielfältige ungeklärte Fragen erschwert und die Situation wird noch komplizierter, wenn sich ein Patient einer gewichtsreduzierenden Operation unterzieht. Postoperative Änderungen der Medikation hängen nicht nur mit der veränderten Pharmakokinetik einzelner Arzneimittel zusammen, sondern auch mit der Änderung von Begleiterkrankungen. Unsere Akten- und Fragebogenauswertung ergab für 88 Patienten eines zertifizierten Adipositas-Chirurgie-Zentrums eine Reduktion des BMI um 18,4 kg/m2 ein Jahr nach Operation bei 71% Schlauchmagenoperationen. Wie erwartet, ging die Gewichtsreduktion mit einem signifikant reduzierten Bedarf an blutzucker- (-76%) und blutdrucksenkenden (-60%) Arzneimitteln einher, der Bedarf an Eisensubstitution stieg an. Entgegen unserer Erwartung blieb die antidepressive Therapie unverändert und die Verordnungen analgetischer Arzneimittel nahmen an. Die Verordnungsraten von Protonenpumpen-Hemmern veränderten sich dynamisch von 50% präoperativ zu annähernd 100% direct postoperativ zu 50% ein Jahr postoperativ, was auch durch die Prophylaxe zur Sicherung der gastrointestinalen Wundheilung zu erklären ist.

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Factors Associated With Achieving a Body Mass Index of Less Than 30 After Bariatric Surgery

Cited by 44 publications

References 35 publications

The Influence of Socioeconomic Factors on Quality-of-Life After Laparoscopic Gastric Bypass Surgery

The Influence of Socioeconomic Factors on Quality-of-Life After Laparoscopic Gastric Bypass Surgery

Causes and solutions to “globesity”: The new fa(s)t alarming global epidemic

Änderungen der Pharmakotherapie nach Adipositas-Chirurgie - eine monozentrische Erhebung

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