Factors associated with amputation among patients with diabetic foot ulcers in a Saudi population

Musa, Imad R.; Ahmed, Mohanned O. N.; Sabir, Elsanousi Ibrahim; Alsheneber, Ibrahim F.; Ibrahim, Elsayed M. E.; Mohamed, Gussay Badawi; Awadallah, Rasha Elamin; Abbas, Tarig; Gasim, Gasim I.

doi:10.1186/s13104-018-3372-z

Cited by 26 publications

(28 citation statements)

References 28 publications

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“…The mean age of the study participants was 56.8 (±12.4) years with about 90% of them aged above 40 years. In the same vein, Al-Rubeaan et al 11 in their retrospective cohort study have reported that “age ⩾45 years is a risk factor for developing diabetic foot ulcers in a Saudi population.” Similarly, more recently, Musa et al 29 in their study of the factors associated with amputation among patients with DF ulcers in the same population highlighted that the “worldwide metabolic syndrome epidemic,” which is particularly affecting the Arabian Gulf area, could be responsible for the younger age of presentation.…”

Section: Discussionmentioning

confidence: 96%

Impaired quality of life and diabetic foot disease in Saudi patients with type 2 diabetes: A cross-sectional analysis

AlSadrah¹

2019

SAGE Open Medicine

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Objectives: This study aimed to assess the overall health-related quality of life in type 2 diabetes mellitus patients with diabetic foot disease compared to diabetic patients without diabetic foot and to identify the clinical utility of this assessment. Methods: A total of 250 consecutive patients with type 2 diabetes mellitus (100/150 with/without diabetic foot, respectively) were interviewed. The questionnaires of the 36-item short-form survey and region-specific foot and ankle ability measure were applied. Wagner–Meggitt wound classification was used for foot-ulcer evaluation. Follow-up of patients for 3–6 weeks was done to identify the potential clinical short outcomes of diabetic foot ulcers. Results: Type 2 diabetes mellitus patients with diabetic foot exhibited poor mental and physical health consequences. Females had more prevalence of forefoot lesions, larger ulcer size, advanced Wagner grade, and higher frequency of unhealed ulcers. Receiver operating characteristic curve analysis demonstrated high value of foot and ankle ability measure and 36-item short-form questionnaires to discriminate type 2 diabetes mellitus patients with and without diabetic foot at cutoff values of 66 and 49.6, respectively. Foot and ankle ability measure questionnaire also showed high performance for differentiating the clinical outcome of foot ulcer. Total foot and ankle ability measure subscale score above the cutoff value of 65.5 could discriminate patients with complete healing and unhealed ulcer lesions at a high sensitivity and specificity. Conclusion: The current findings confirm the impact of diabetic foot disease on type 2 diabetes mellitus overall health-related quality of life reflected in 36-item short-form questionnaire and foot and ankle ability measure questionnaire which showed high discriminative values for type 2 diabetes mellitus patient sub-grouping. Their application in routine clinical health assessment with continuous medical education programs is highly recommended to achieve a better health-related quality of life.

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Section: Discussionmentioning

confidence: 96%

Impaired quality of life and diabetic foot disease in Saudi patients with type 2 diabetes: A cross-sectional analysis

AlSadrah¹

2019

SAGE Open Medicine

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“…This finding was comparable with Al-Rubeaan et al [7] in their retrospective cohort study where they reported that “age ≥ 45 years is a risk factor for developing diabetic foot ulcers in Saudi population”. Similarly, in the study about the factors associated with amputation among DF ulcer patients in Saudi population, Musa and his colleagues [16], recently highlighted the “epidemic of metabolic syndrome around the world”, which particularly affects the Gulf region, being responsible for a younger age at the onset of the disease.…”

Section: Discussionmentioning

confidence: 99%

Factors associated with diabetic foot among type 2 diabetes in Northern area of Saudi Arabia: a descriptive study

et al. 2019

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ObjectiveFoot complications are considered to be a devastating consequence of type 2 diabetes mellitus (T2DM), posing a major medical and economic burden. A prospective study was conducted at researchers’ area “Northern area of Saudi Arabia” to determine the factors associated with diabetic foot (DF) among T2DM patients. Identifying the extent of this problem and the associated factors will enable the health providers to imply early preventive measurements.ResultsTwo hundred T2DM patients with/without DF (n = 100 for each group) were recruited. In total, the mean (SD) age of participants was 56 (± 12.2) years and nearly 70% of the patients were females. They showed a trend for higher frequency of impaired vibration perception, light touch pressure, proprioception and pain sensation than males in T2DM with DF. In univariate analysis, older age, long duration of diabetes and poor glycemic control reflected in high levels of HbA1c were significant factors associated with DF (OR = 4.1, 95% CI 2.3–7.4, P < 0.0001; OR = 6.5, 95% CI (4.9–9.3), P < 0.0001, and OR = 1.1, 95% CI (1.05–1.3), P = 0.002, respectively). Taken together, the current results could highlight the importance of epidemiological studies to raise the awareness of this important health care problem around the country.

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“…10 Musa, et al (2018) found that old age was the risk factor for lower extremity amputation in diabetic foot patients. 6 They stated that elderly patients had poor prognosis in wound healing because of a reduced immune response to infection and other comorbid diseases that slowed wound healing. 6 The difference in this study could be caused due to differences in the number of samples used.…”

Section: Discussionmentioning

confidence: 99%

“…6 They stated that elderly patients had poor prognosis in wound healing because of a reduced immune response to infection and other comorbid diseases that slowed wound healing. 6 The difference in this study could be caused due to differences in the number of samples used. The sample in this study did not meet the minimum sample of 23 patients for each group so that the results could be affected.…”

Section: Discussionmentioning

confidence: 99%

“…5 The unhealed ulcer can lead to lower extremity amputation. 6 Diabetic foot ulcer is one of the highest causes of non-traumatic amputation in the world and the most feared consequences for diabetic patients. 7 Risk factors for lower extremity amputation in diabetic foot ulcer patients are peripheral neuropathy, peripheral arterial disease, foot deformity, retinopathy, uncontrolled blood glucose level, history of diabetic foot ulcer/amputation, 8 and old age.…”

Section: Introductionmentioning

confidence: 99%

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Risk Factors for Lower Extremity Amputation in Diabetic Foot Ulcer Patients: A Case-Control Study

Dewi

Wibisono

Pawana

2020

Universitas Airlangga

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Introduction: Diabetes mellitus is a metabolic syndrome that is marked by higher blood glucose. The uncontrolled high blood glucose can lead to complication, such as diabetic foot. Diabetic foot is the most reason why diabetic patients are hospitalized. Diabetic foot that cannot heal may lead to lower extremity amputation. The purpose of this study was to describe the risk factors of lower extremity amputation in diabetic foot ulcer patients.Methods: This study used a case-control study of diabetic foot patients in Dr. Soetomo General Hospital from January 2015 to December 2017. This study used the data from medical records in Inpatient Installation Department of Internal Medicine. Patients with diabetic foot ulcer and lower extremity amputation due to diabetes were included in this study. Incomplete medical records were excluded. Data of samples were divided to two groups, i.e. the amputation group and the non-amputation group with a ratio of 1:1. Risk factors of amputation that were analyzed were male, old age, and the history of ulcer/lower extremity amputation.Results: Based on the data of 36 samples, there were 11 male patients (61.1%) and 7 female patients (38.9%) who experienced lower extremity amputation. The average age of amputation group was 59.61 years old with a range of ages from 39 to 72 years old. This study found the risk factors for lower extremity amputation in diabetic foot ulcer patients was the history of ulcer/amputation due to diabetes (OR 5.0, 95% CI 1.065-23.464, p = 0.034). Conclusion: The risk factor for lower extremity amputation in diabetic foot ulcer patients was the history of ulcer/amputation due to diabetes.

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Factors associated with amputation among patients with diabetic foot ulcers in a Saudi population

Cited by 26 publications

References 28 publications

Impaired quality of life and diabetic foot disease in Saudi patients with type 2 diabetes: A cross-sectional analysis

Impaired quality of life and diabetic foot disease in Saudi patients with type 2 diabetes: A cross-sectional analysis

Factors associated with diabetic foot among type 2 diabetes in Northern area of Saudi Arabia: a descriptive study

Risk Factors for Lower Extremity Amputation in Diabetic Foot Ulcer Patients: A Case-Control Study

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