Factors associated with anxiety disorders among HIV-positive attendees of an HIV clinic in Lagos, Nigeria

Olagunju, Andrew T; Adeyemi, Joseph D.; Erinfolami, Adebayo R.; Ogundipe, O A

doi:10.1258/ijsa.2011.011200

Cited by 17 publications

(14 citation statements)

References 14 publications

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“…30 39 In one of them, 39 PLWH50 + on ART presented with the same proportion of anxiety symptoms with HIV uninfected older adults at 3%. In the other study, 30 the prevalence of anxiety disorders among PLWH50 + on ART was 21% compared with 22% in HIV infected young adults (18-50 years).…”

Section: Prevalence Of Depression and Anxietymentioning

confidence: 74%

Mental health and well-being of older adults living with HIV in sub-Saharan Africa: a systematic review

et al. 2021

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ObjectiveIn this systematic review, we aimed to summarise the empirical evidence on common mental disorders (CMDs), cognitive impairment, frailty and health-related quality of life (HRQoL) among people living with HIV aged ≥50 years (PLWH50 +) residing in sub-Saharan Africa (SSA). Specifically, we document the prevalence and correlates of these outcomes.Design, data sources and eligibility criteriaThe following online databases were systematically searched: PubMed, CINAHL, PsycINFO, Embase and Scopus up to January 2021. English-language publications on depression, anxiety, cognitive function, frailty and quality of life among PLWH50+ residing in SSA were included.Data extraction and synthesisWe extracted information, including study characteristics and main findings. These were tabulated, and a narrative synthesis approach was adopted, given the substantial heterogeneity among included studies.ResultsA total of 50 studies from fifteen SSA countries met the inclusion criteria. About two-thirds of these studies emanated from Ethiopia, Uganda and South Africa. Studies regarding depression predominated (n=26), followed by cognitive impairment (n=13). Overall, PLWH50+ exhibited varying prevalence of depression (6%–59%), cognitive impairments (4%–61%) and frailty (3%–15%). The correlates of CMDs, cognitive impairment, frailty and HRQoL were rarely investigated, but those reported were sociodemographic variables, many of which were inconsistent.ConclusionsThis review documented an increasing number of published studies on HIV and ageing from SSA. However, the current evidence on the mental and well-being outcomes in PLWH50+ is inadequate to characterise the public health dimension of these impairments in SSA, because of heterogeneous findings, few well-designed studies and substantial methodological limitations in many of the available studies. Future work should have sufficiently large samples of PLWH50+, engage appropriate comparison groups, harmonise the measurement of these outcomes using a standardised methodology to generate more robust prevalence estimates and confirm predictors.PROSPERO registration numberCRD42020145791.

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Section: Prevalence Of Depression and Anxietymentioning

confidence: 74%

Mental health and well-being of older adults living with HIV in sub-Saharan Africa: a systematic review

et al. 2021

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“…Psychiatric disorders occur in up to 50% of individuals with HIV (12–15). The most commonly reported of these are depression, anxiety disorders and substance use disorders (14,16–18). The role of these disorders in reducing quality of life and accelerating the progression of HIV disease(19–21) is mediated through a number of factors, including an increased likelihood of suboptimal treatment adherence (22–24).…”

Section: Introductionmentioning

confidence: 99%

“…12–15 The most commonly reported of these are depression, anxiety disorders and substance use disorders. 14,16–18 These disorders act to reduce quality of life and accelerate the progression of HIV disease 19–21 through a number of mechanisms, including an increased likelihood of suboptimal treatment adherence. 22–24 Much research has demonstrated associations between psychiatric disorders and ART adherence.…”

Section: Introductionmentioning

confidence: 99%

Psychiatric disorders and adherence to antiretroviral therapy among a population of HIV-infected adults in Nigeria

et al. 2015

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Psychiatric disorders are common among HIV patients in Nigeria. Adherence is necessary to optimize the outcome of antiretroviral therapy. In this study, we aimed to identify associations between antiretroviral adherence measured by 1-week and 1-month self-reported missed doses, and psychiatric illness in a cohort previously assessed for psychiatric disorders using the Composite International Diagnostic instrument (CIDI). The study participants comprised 151 adults with major depression, anxiety or suicidal symptoms, and 302 matched-control participants. Two controls were randomly selected for each case within the same gender and education stratum. We compared participants with psychiatric disorders (WPDs) and without psychiatric disorders (NPDs) on selected demographic and clinical variables, in addition to adherence. Participants with 1 or more missed doses in the preceding month had twice the odds of having a major depressive episode as those with no missed doses during this period (OR 2.22, 95% CI 1.03, 4.79). This association remained significant after adjusting for selected risk factors. There was no statistically significant difference between WPD and NPD groups on either 1-week or 1-month adherence, or on age, marital status, occupational class, HIV viral load at enrollment or current CD4. Among Nigerian adults with HIV, suboptimal antiretroviral adherence is associated with, and could be a pointer to depression. Routine self-report adherence assessments may have potential utility for identifying individuals at risk among this population.

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“…Other than that, 89% of patients with HIV who were diagnosed to have GAD were single. Single patients had increased odds of having anxiety by 3.6 times compared to the patients who were married (Ngocho et al, 2019) and similar studies showed that being unmarried had 2-times higher risk to develop anxiety (p=0.002) (Olagunju et al, 2012). HIVinfection is a chronic disease which needs endless support as they face various social challenges.…”

Section: Discussionmentioning

confidence: 97%

Common Psychological Disorder among Patients with Retroviral Disease

Jaris

Chidambaram

Kaur

et al. 2021

jABs

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Major depressive disorder (MDD) and generalized anxiety disorder (GAD) increases further morbidity and mortality of patients with retroviral disease (RVD). This study aimed to determine the prevalence and the contributing factors of MDD and GAD. The symptoms were screened using the Hospital Anxiety Depression Scale (HADS), MDD and GAD was diagnosed with the Mini International Neuropsychiatric Interview (MINI). 27(12.9%) patients had MDD and 28(13.0%) had GAD. The contributing factors include illicit drug use in the past, social support system, and CD4 count. Interventions for RVD patients should include counselling for those abusing drugs, increasing support system and adherence to treatment. Keywords: Retroviral Disease, Anxiety, Depression, Support system eISSN 2514-7528 © 2021 The Authors. Published for AMER ABRA CE-Bs by E-International Publishing House, Ltd., UK. This is an open-access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer-review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians / Africans / Arabians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia. DOI: https://doi.org/10.21834/jabs.v6i18.380

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Factors associated with anxiety disorders among HIV-positive attendees of an HIV clinic in Lagos, Nigeria

Cited by 17 publications

References 14 publications

Mental health and well-being of older adults living with HIV in sub-Saharan Africa: a systematic review

Mental health and well-being of older adults living with HIV in sub-Saharan Africa: a systematic review

Psychiatric disorders and adherence to antiretroviral therapy among a population of HIV-infected adults in Nigeria

Common Psychological Disorder among Patients with Retroviral Disease

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