Factors Associated With Colorectal Cancer Screening Among First-Degree Relatives of Patients With Colorectal Cancer in China

Abstract

BackgroundFirst-degree relatives of patients with colorectal cancer have an elevated risk of colorectal cancer. However, the behavior and factors potential influencing first-degree relatives regarding colorectal cancer screening in China remain unknown.ObjectiveThe aim of this study was to explore the screening behavior and related factors of first-degree relatives of colorectal cancer patients.MethodsA cross-sectional design was applied, and 201 first-degree relatives participated from August 2018 to July 2019. Data were collected about demographic information, the “Colorectal Cancer Perceptions Scale,” and screening behavior of first-degree relatives. Factors associated with screening behavior were identified using logistic regression analysis.ResultsOnly 18.9% of first-degree relatives had participated in colonoscopy screening. Two Health Belief Model factors were the influencing factors of their participation in colorectal cancer screening. Higher possibility of colorectal cancer screening of first-degree relatives was associated with higher perceived susceptibility (odds ratio, 1.224; 95% confidence interval, 1.075–1.395) and lower perception of barriers (odds ratio, 0.880; 95% confidence interval, 0.820–0.944) of first-degree relatives.ConclusionsParticipation in colorectal cancer screening by first-degree relatives requires improvement; perceived susceptibility and perception of barriers were the most important predictors.Implications for PracticeHealth professionals can enhance awareness of colorectal cancer susceptibility and address barriers to colorectal cancer screening among first-degree relatives at both individual and social levels.

Factors affecting colonoscopy screening among first‐degree relatives of colorectal cancer patients: A mixed‐method systematic review

“…Meanwhile, some FDRs indicated that they had other activities which were more important than colonoscopy (McGarragle et al., 2019; Tan et al., 2017, 2020; Zhang et al., 2021). Concerns about pain or discomfort also hindered FDRs from undergoing colonoscopy (Bai et al., 2020; Bronner et al., 2013; Du et al., 2022; Harris et al., 1998; Ingrand et al., 2008; Murff et al., 2008; Sun et al., 2022; Tan et al., 2017, 2020). Besides, FDRs expressed their concern about bowel preparation, such as the drink, enema, and sedation (Bronner et al., 2013; Harris et al., 1998; Ingrand et al., 2008; McGarragle et al., 2019; Sun et al., 2022; Taouqi et al., 2010).…”

“…Policy‐related factors included cost and health insurance. The cost of colonoscopy was reported as a hindrance for FDRs to undergo colonoscopy screening (Bronner et al., 2013; Chouhdari et al., 2019; Du et al., 2022; Harris et al., 1998; Kilickap et al., 2012; Murff et al., 2008; Rawl et al., 2005; Sun et al., 2022; Tan et al., 2017, 2020; Taouqi et al., 2010). In addition, lack of insurance was reported as a barrier, and the related findings should be divided into two groups (Bronner et al., 2013; Chouhdari et al., 2016; Tan et al., 2020).…”

“…In some studies, FDRs who perceived that they were susceptible to CRC were more likely to undergo colonoscopy (Adakan et al., 2014; Du et al., 2022; Harris et al., 1998; Ingrand et al., 2008; Taouqi et al., 2010; Weigl et al., 2020) whereas the other three studies did not find an association between susceptibility perception and colonoscopy screening behavior (Bai et al., 2020; Koc & Esin, 2014; Santos et al., 2011).…”

“…FACTORS AFFECTING FDRs' COLONOSCOPY SCREENING Du et al, 2022;Harris et al, 1998;Ingrand et al, 2008;Taouqi et al, 2010;Weigl et al, 2020) whereas the other three studies did not find an association between susceptibility perception and colonoscopy screening behavior (Bai et al, 2020;Koc & Esin, 2014;Santos et al, 2011).…”

Effectiveness of a tailored communication intervention on colonoscopy uptake for firstdegree relatives of colorectal cancer patients: A randomized controlled trial

“… 10 , 11 In China, the situation is even worse, as less than 20% of people received recommended colonoscopy screening despite screening being covered by insurance. 12 , 13 , 14 The low participation rate is a global problem that threatens the effectiveness of screening programs for the at-risk population. 15 …”