Factors associated with compliance in treatment of tuberculosis

Menzies, Richard; Rocher, Isabelle; Vissandjée, Bilkis

doi:10.1016/0962-8479(93)90066-7

Cited by 74 publications

(54 citation statements)

References 10 publications

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“…Defaulting on TB medication is a major barrier to its local and global control. In addition, defaulting increases the risk of drug resistance, relapse and death, and may prolong infectiousness (11)(12)(13)(14)(15). The TB patient treatment default rate is about 10% in Sudan (5) and 14% in Khartoum State (16).…”

Section: Introductionmentioning

confidence: 99%

Disease and treatment-related factors associated with tuberculosis treatment default in Khartoum State, Sudan: a case-control study

Ali¹,

Prins²

2017

East Mediterr Health J

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Facteurs pathologiques et thérapeutiques entraînant un abandon du traitement de la tuberculose dans l'État de Khartoum, Soudan : étude cas-témoin RÉSUMÉ L'abandon du traitement de la tuberculose (TB) demeure un défi dans la lutte antituberculeuse. La présente étude cas-témoin avait pour objectif d'identifier les déterminants de l'abandon de traitement parmi les patients atteints de tuberculose pris en charge dans des centres de traitement dans l'État de Khartoum entre mai et juillet 2011. Les cas comprenaient des patients atteints de tuberculose et ayant abandonné leur traitement, et les témoins étaient ceux ayant mené leur traitement à terme. Sur les 2727 patients atteints de tuberculose traités dans les centres, 328 (14 %) avaient abandonné le traitement. Sur ce nombre, 185 avaient repris le traitement avant la collecte des données, et 143 étaient restés sans traitement et étaient donc éligibles comme cas. Sur les 143, 27 n'ont pu être tracés et 11 ont refusé de participer. Ainsi, 105 cas et 210 témoins ont été inclus et interrogés. Les variables associées de façon significative avec l'abandon de traitement étaient le fait d'habiter en zone rurale (OR = 2,68 ; IC à 95 % I 1,51-4,73), la non participation à un programme DOTS (traitement de brève durée sous surveillance directe) (OR = 2,53 ; IC à 95 % 1,49-4,30), le développement d'effets secondaires (OR = 1,94 ; IC à 95 % 1,14-3,29) et des antécédents de tuberculose (rechute, tuberculose multirésistante ou échec du traitement) (OR = 5,11 ; IC à 95 % 2,69-9,6). Une attention devrait être accordée à ces groupes à risque d'abandon de façon à encourager l'observance et la poursuite du traitement. ‫ضابطة‬ ‫حالة‬ ‫دراسة‬ ‫السودان:‬ ‫اخلرطوم،‬ ‫والية‬ ‫يف‬ ‫السل‬ ‫عالج‬ ‫عن‬ ‫التخلف‬ ‫إىل‬ ‫تؤدي‬ ‫التي‬ ‫والعالج‬ ‫باملرض‬ ‫املرتبطة‬ ‫العوامل‬

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Section: Introductionmentioning

confidence: 99%

Disease and treatment-related factors associated with tuberculosis treatment default in Khartoum State, Sudan: a case-control study

Ali¹,

Prins²

2017

East Mediterr Health J

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“…This clinical improvement in the first months of treatment is crucial for some patients because it may discourage the person to continue to therapy, as he thinks that he is cured [37][38][39].…”

Section: Discussionmentioning

confidence: 99%

Accession To Tuberculosis Treatment: Individual And Social Vulnerability Elements

et al. 2015

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Introduction: Tuberculosis (TB) remains as a major public health problem, being the second infectious disease to cause death all over the world. The Directly Observed Treatment (DOT) is one of the recommended strategies to control this disease. The accession in this mode of treatment is integrated into the Tuberculosis Control Program (PCT), this program also provide socio-economic incentives as the distribution of food baskets, bus passes and breakfast. Moreover, public policies for social protection help both family development and social vulnerability. Tuberculosis is still associated with social exclusion and marginalization of the population subjected to poor living conditions and limited access to public services.Objective: Analyze the potential accession to tuberculosis treatment related to individual and social vulnerability aspects. Methods:Cross-sectional, qualitative study, conducted with 39 individuals diagnosed with tuberculosis and in treatment for at least 30 days in the city of Campina Grande, Paraiba, Brazil. 20 markers were used as analysis units, with the possibility of score responses from one to three. The lower scores indicate lower potential of adherence to treatment, while the highest ones express greater potential accession.Results: xx markers that were more related to score one and indicated lower potential adherence to tuberculosis treatment were: tuberculosis impact on labor; conception of health-disease causality and work process (employment status). In contrast, markers that were more closely related to the score three that resonate with greater

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“…The end result of this situation is a poor control of tuberculosis and a failure of the National Tuberculosis Control Program to achieve its goals. 11,13 Long periods of hospitalization can solve some of the problems but would be impractical and expensive. Retrieval systems (phone, letters, home visits, etc.)…”

Section: Discussionmentioning

confidence: 99%

“…8 It is a well-known fact that compliance with prescribed drugs is the most important single factor in the success of tuberculosis treatment programs. [9][10][11] Even if a patient attends clinics regularly, it is still uncertain whether he/she takes the prescribed medications. Consequently, drug resistance (particularly multi-drug resistance) increases, which is another problem facing health planners.…”

Section: Discussionmentioning

confidence: 99%

The Outcome of Tuberculosis Treatment after Implementation of the National Tuberculosis Control Program in Saudi Arabia

Al-Hajjaj

2000

Ann Saudi Med

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Factors associated with compliance in treatment of tuberculosis

Cited by 74 publications

References 10 publications

Disease and treatment-related factors associated with tuberculosis treatment default in Khartoum State, Sudan: a case-control study

Disease and treatment-related factors associated with tuberculosis treatment default in Khartoum State, Sudan: a case-control study

Accession To Tuberculosis Treatment: Individual And Social Vulnerability Elements

The Outcome of Tuberculosis Treatment after Implementation of the National Tuberculosis Control Program in Saudi Arabia

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