Factors Associated with Drug Adherence and Blood Pressure Control in Patients with Hypertension

Abstract

Age, sex, race and depression are associated with antihypertensive drug adherence and blood pressure control. Self-reported and refill adherences appear to provide complementary information and are associated with reductions in systolic and diastolic blood pressure of similar magnitude.

Do socioeconomic disparities affect accessing and keeping antihypertensive drug therapy? Evidence from an Italian population-based study

“…2,3 Socioeconomic factors, such as income, education and ethnicity, have been extensively investigated as possibly associated with the rate of treatment and control of hypertension. [4][5][6][7][8][9] However, data on this issue mainly reflect private, or mixed publicprivate, health care systems. Despite the fact that the Italian National Health Service (NHS) provides universal coverage for health care, including drug treatment for hypertension, socioeconomic disparities in the occurrence of coronary heart disease still persist.…”

Achieving blood pressure goals globally: five core actions for health-care professionals. A worldwide call to action

“…34,35 Comorbid conditions, notably depression, may also impact on a patient's ability to adhere and persist with antihypertensive treatment. 36 The relationships between health-care professionals and the patient are crucial to overcoming patient-related barriers to blood pressure control. Management styles that are autocratic or lack meaningful interaction with the patient are unlikely to deliver acceptable goal rates.…”

Comparison of hypertension management between cancer survivors and the general public

“…Our previous study showed similar antihypertensive medication adherence between cancer survivors and the comparison group (84.0% vs. 85.6%) using the claim data set. 17 The agreement between selfreported adherence and refill adherence is reported to be only poor to fair, 9,22 and it has been suggested that these two methods reflect different dimensions of medication-taking behavior. 34 Other potential explanations would be increased awareness of non-cancer care among cancer survivors between the study period (2002 vs. 2009), 35,36 and insufficient adjustment of potential confounders, such as education, employment status and smoking, in the previous study.…”

“…[5][6][7][8][9] According to the Health Belief Model, certain behavioral factors, such as perceived risk for the disease and perceived benefit of treatment, [10][11][12] could also affect the management of hypertension. Unlike hypertensive patients without cancer, cancer survivors with hypertension are more likely to consider cancer recurrence, metastasis and a second primary cancer as major health concerns, and usually require more complex care.…”