“…All studies included in our meta-analysis were of high quality. One study [ 18 ] categorized opioids into strong and weak opioids. Since the results of strong and weak opioids could not be combined, the results of strong opioids were used to best reflect the effects of opioids on clinical outcomes.…”
Section: Resultsmentioning
confidence: 99%
“…There was substantial heterogeneity across the studies. Subgroup analysis based on countries (U.S.A versus South Korea) and sensitivity analysis by excluding one study [ 18 ] revealed non-significant results for mortality rate with an unadjusted OR = 1.853 (95% CI:0.875–3.925; P = 0.107;I 2 = 98.9%) and adjusted OR = 1.306 (95% CI: 0.870–1.961; P = 0.197; I 2 = 92.4%). Fig.…”
Section: Resultsmentioning
confidence: 99%
“…Individuals with opioid use disorder may also be more susceptible to primary COVID-19 infection due to the extensive public health measures implemented. Social distancing practices may contribute to reduced drug availability, disrupted access to health services and safe consumption sites, and isolation can negatively affect mental health and predispose opioid use [ 18 ].…”
Section: Discussionmentioning
confidence: 99%
“…Currently, more information is needed before prediction models for COVID-19 can be recommended for clinical guidance [ 18 ]. Proposed prognostic models to date have considered a combination of features derived from computed tomography scoring, lactate dehydrogenase, C reactive protein, lymphocyte count, comorbidity, age, and sex as predictors [ 18 ]. The significant biopsychosocial effects associated with opioid use warrant its investigation as a prognostic factor.…”
“…All studies included in our meta-analysis were of high quality. One study [ 18 ] categorized opioids into strong and weak opioids. Since the results of strong and weak opioids could not be combined, the results of strong opioids were used to best reflect the effects of opioids on clinical outcomes.…”
Section: Resultsmentioning
confidence: 99%
“…There was substantial heterogeneity across the studies. Subgroup analysis based on countries (U.S.A versus South Korea) and sensitivity analysis by excluding one study [ 18 ] revealed non-significant results for mortality rate with an unadjusted OR = 1.853 (95% CI:0.875–3.925; P = 0.107;I 2 = 98.9%) and adjusted OR = 1.306 (95% CI: 0.870–1.961; P = 0.197; I 2 = 92.4%). Fig.…”
Section: Resultsmentioning
confidence: 99%
“…Individuals with opioid use disorder may also be more susceptible to primary COVID-19 infection due to the extensive public health measures implemented. Social distancing practices may contribute to reduced drug availability, disrupted access to health services and safe consumption sites, and isolation can negatively affect mental health and predispose opioid use [ 18 ].…”
Section: Discussionmentioning
confidence: 99%
“…Currently, more information is needed before prediction models for COVID-19 can be recommended for clinical guidance [ 18 ]. Proposed prognostic models to date have considered a combination of features derived from computed tomography scoring, lactate dehydrogenase, C reactive protein, lymphocyte count, comorbidity, age, and sex as predictors [ 18 ]. The significant biopsychosocial effects associated with opioid use warrant its investigation as a prognostic factor.…”
“…Close to 5% (4.2%) of respondents reported an overdose. Other challenges that were identified included COVID-19 impacting treatment services and difficulties accessing specific services like naloxone and needle exchanges (22). The Addiction Policy Forum cited some perspectives from individuals in recovery or those with an active SUD.…”
Section: Substance Use Behaviors and Disordersmentioning
COVID-19 was first identified in Wuhan, China in December of 2019 and appeared in the United States 1 month later. Between the onset of the pandemic and January 13, 2021, over 92 million people have tested positive for the virus and over 1.9 million people have died globally. Virtually every country in the world has been impacted by this virus. Beginning in March 2020, many U.S. state governments enforced a “quarantine” to respond to the growing health crisis. Citizens were required to remain at home; schools, restaurants, and non-essential businesses were forced to close, and large gatherings were prohibited. Americans' lives were transformed in a span of days as daily routines were interrupted and people were shuttered indoors. Mounting fear and unpredictability coupled with widespread unemployment and social isolation escalated anxiety and impacted the mental health of millions across the globe. Most (53%) U.S. adults reported that the coronavirus outbreak has had a negative impact on their mental health, including inducing or exacerbating use of alcohol, drugs, gambling and overeating as coping mechanisms. In this paper, we will examine substance use and addictive behaviors that have been used to manage the stress and uncertainty wrought by the COVID-19 pandemic. We review the changing treatment landscape as therapy pivoted online and telemedicine became the norm.
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