Factors associated with effective reassessment of antibiotic therapy on day 3

Roger, P. M.; Labate, C.; Serre, S.; Zumbo, C.; Valerio, Luca; Bonnet, H; Jurado, Alberto; Bele, Nicolas; Brofferio, P.

doi:10.1016/j.medmal.2012.12.007

Cited by 8 publications

(4 citation statements)

References 17 publications

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“…However, in this study, using AOFs was statistically significantly associated with increasing microbiological analysis but not statistically significantly associated with antibiotic prescribing change. This finding was similar to a study by Roger et al (2013) in which they found microbiological findings were not contributive to a modification of the initial antibiotic treatment.…”

Section: Prescribing Patterns For the Patient With Community-acquired...supporting

confidence: 91%

The use of an antibiotic order form in a tertiary hospital: Influence on physicians’ prescribing patterns

Vo¹,

Anh²,

Nguyen³

et al. 2021

J Pharm Pharmacogn Res

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Context: Vietnam is one of the countries at the high alert of antibiotic resistance. Aims: To evaluate the compliance rate and changes in physicians’ prescribing patterns in patients with community-acquired pneumonia (CAP) before and after using the antibiotic order form (AOF) in a tertiary hospital. Methods: 120 inpatient medical records having antibiotic use and 115 patient medical records diagnosed with CAP at a Department of Respiratory Medicine during 3 months before and 3 months after using the AOF were retrospectively collected for assessment. Results: The compliance rate was 92%, and the average rate of filling in information fields was 58%. Comparison of prescribing behavior of CAP in control and intervention group showed that the rate of bacterial culture increased from 70% to 77% (p = 0.690), in which the rate of culture prior prescribing administration increased from 14% to 45% (p < 0.001), the initial antibiotic regimen with narrow-spectrum increased from 26% to 36% (p = 0.353), the proportion of patients improved clinically after 72 hours increased from 64% to 89% (p = 0.138), and the de-escalation decreased from 23% to 20% (p = 0.713). The treatment failure at hospital discharge decreased from 12% to 6% (p = 0.447). However, the length of treatment and the days of antibiotic treatment were not significantly different. Conclusions: The compliance rate was high, but the AOF filling rate was incomplete. Improving prescribing patterns and treatment efficacy in CAP patients is a suggestion to combine the AOF into multifaceted interventional efforts for specific patients.

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Section: Prescribing Patterns For the Patient With Community-acquired...supporting

confidence: 91%

The use of an antibiotic order form in a tertiary hospital: Influence on physicians’ prescribing patterns

Vo¹,

Anh²,

Nguyen³

et al. 2021

J Pharm Pharmacogn Res

View full text Add to dashboard Cite

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“…Found (39%) of lung infections, (18%) urinary tract and (13%) gastrointestinal. In Nice, Roger et al [24]. Also identified diagnostics focusing on the broncho-pulmonary infections in 43% and 13% in urine.…”

Section: Diagnosismentioning

confidence: 99%

“…Martinez et al found that more than half of first-line therapy (55.3%) had been modified after a re-evaluation at 48-72 hours [21]. This revaluation at 48-72 hours is a good practice for appropriate antibiotic use aiming at assessing the effectiveness of treatment, adapting the antibiotic treatment to the results of susceptibility testing, and especially helping to choose antibiotics with narrower spectrum [24]. The need for continued antibiotic therapy should be evaluated daily to avoid too short or too long administration.…”

Section: Prescriptionmentioning

confidence: 99%

Evaluation of the Quality of Prescription of Antibiotics with Curative Intent in a Specialized Department in Dakar, Senegal

2018

AIDT

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Background:Wide prescription and misuse of antibiotics have led to the emergence of resistant bacteria. The evaluation of professional practices is a way of contributing to the improvement of prescription. Our work aimed at assessing the quality of antibiotics prescription with curative intent in a clinic of infectious diseases in Dakar with reference to national recommendations.Methods: A observational study was conducted from April 2 to July 2, 2012 based on the records of all hospitalized patients, aged 15 and above, having received antibiotic therapy with curative intent. The quality of the prescription was evaluated according to the national recommendations of PRONALIN which served as a reference. Thus two levels of appreciation, appropriate and inappropriate were used.Results: During the period from 02/04/2012 to 02/07/2012, 170 patients received antibiotic therapy (53.79%), among whom 267 antibiotic prescriptions were made. Monotherapy was received by 57.70% of patients. The most prescribed antibiotic family was β-lactams (55.43%). Antibiotic therapy was probabilistic in 155 (91.18%) prescriptions. Compliance rate of antibiotic prescription to national recommendations was 74.7%. The prescriptions according to the molecules were appropriate in 97.37% of the cases. Dosages were adequate in the majority of prescriptions (90.63%). The routes of administration were observed for almost all of molecules (98.87%). The duration of treatment was not appropriate in 119 cases (44.56%). Only 15.9% of antibiotic therapy was assessed at 48 hours. Conclusion:Compliance rate of antibiotic prescription to national recommendations was 74.7% in this infectious disease department of Dakar mainly due to unfulfilled treatment times and the lack of evaluation of antibiotic therapy after 48 hours of administration. Although the prescription of antibiotics in this clinic specializing in infectious diseases remains good, the emphasis should be on regular training of health workers and on better dissemination of national guidelines.

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“…Such IV-PO switches are often considered approximately three days after starting the empiric therapy if the patient is clinically stable and is able to swallow (6,7). Changing the administration route may be performed while ordering the same or a different antimicrobial agent, depending on the microbiological susceptibility results.…”

Section: Introductionmentioning

confidence: 99%

Earlier switching from intravenous to oral antibiotics owing to electronic reminders

Beeler

Kuster

Eschmann

et al. 2015

International Journal of Antimicrobial Agents

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Paper-based interventions have been shown to stimulate switching from intravenous (i.v.) to oral (p.o.) antibiotic therapies. Shorter i.v. durations are associated with a lower risk of iatrogenic infections as well as reduced workload and costs. The purpose of this study was to determine whether automated electronic reminders are able to promote earlier switching. In this controlled before-and-after study, an algorithm identified patients who were eligible for i.v.-to-p.o. switch 60h after starting i.v. antimicrobials. Reminders offering guidance on the re-assessment of initial i.v. therapy were displayed within the electronic health records in 12 units during the intervention period (year 2012). In contrast, no reminders were visible during the baseline period (2011)

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Factors associated with effective reassessment of antibiotic therapy on day 3

Cited by 8 publications

References 17 publications

The use of an antibiotic order form in a tertiary hospital: Influence on physicians’ prescribing patterns

The use of an antibiotic order form in a tertiary hospital: Influence on physicians’ prescribing patterns

Evaluation of the Quality of Prescription of Antibiotics with Curative Intent in a Specialized Department in Dakar, Senegal

Earlier switching from intravenous to oral antibiotics owing to electronic reminders

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