Factors associated with health‐related quality of life in community‐dwelling elderly people in China

Wang, Qiumei; Liu, Xiaohong; Zhu, Minglei; Pang, Haiyu; Kang, Lin; Zeng, Ping; Ge, Nan; Qu, Xuan; Chen, Wei; Xia, Hong

doi:10.1111/ggi.13895

Cited by 10 publications

(8 citation statements)

References 28 publications

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“…On the other hand, diabetic patients maintaining high level of physical activity and exercise were exhibited better QoL [54]. Finally, CIRS was found associated with QoL in community-dwelling older adults [55], as was polypharmacy [56]. Thus, our findings that the addition of these variables to the multivariable models may blunt the association between CKD and QoL further strengthen their role as important correlates of QoL among older people and suggests that the impact of CKD on QoL may be at least partly mediated by risk factors typically observed among older people.…”

Section: Discussionmentioning

confidence: 90%

Impaired kidney function is associated with lower quality of life among community-dwelling older adults

et al. 2020

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Background Quality of life (QoL) refers to the physical, psychological, social and medical aspects of life that are influenced by health status and function. The purpose of this study was to measure the self-perceived health status among the elderly population across Europe in different stages of Chronic Kidney Disease (CKD). Methods Our series consisted of 2255 community-dwelling older adults enrolled in the Screening for Chronic Kidney Disease (CKD) among Older People across Europe (SCOPE) study. All patients underwent a comprehensive geriatric assessment (CGA), including included demographics, clinical and physical assessment, number of medications taken, family arrangement, Geriatric Depression Scale (GDS), Cumulative Illness Rating Scale, History of falls, Lower urinary tract symptoms, and Short Physical Performance Battery (SPPB). Estimated glomerular filtration rate (eGFR) was calculated by Berlin Initiative Study (BIS) equation. Quality of life was assessed by Euro Qol questionnaire (Euro-Qol 5D) and EQ-Visual Analogue Scale (EQ-VAS). The association between CKD (eGFR < 60, < 45 ml or < 30 ml/min/1.73m2) and low EQoL-VAS was investigated by multivariable logistic regression models. Results CKD was found to be significantly associated with low EQoL-VAS in crude analysis (OR = 1.47, 95%CI = 1.16–1.85 for eGFR< 60; OR = 1.38, 95%CI = 1.08–1.77 for eGFR< 45; OR = 1.57, 95%CI = 1.01–2.44). Such association was no longer significant only when adjusting for SPPB (OR = 1.20, 95%CI = 0.93–1.56 for eGFR< 60; OR = 0.87, 95%CI = 0.64–1.18 for eGFR< 45; OR = 0.84, 95%CI = 0.50–1.42), CIRS and polypharmacy (OR = 1.16, 95%CI = 0.90–1.50 for eGFR< 60; OR = 0.86, 95%CI = 0.64–1.16 for eGFR< 45; OR = 1.11, 95%CI = 0.69–1.80) or diabetes, hypertension and chronic obstructive pulmonary disease (OR = 1.28, 95%CI = 0.99–1.64 for eGFR< 60; OR = 1.16, 95%CI = 0.88–1.52 for eGFR< 45; OR = 1.47, 95%CI = 0.92–2.34). The association between CKD and low EQoL-VAS was confirmed in all remaining multivariable models. Conclusions CKD may significantly affect QoL in community-dwelling older adults. Physical performance, polypharmacy, diabetes, hypertension and COPD may affect such association, which suggests that the impact of CKD on QoL is likely multifactorial and partly mediated by co-occurrent conditions/risk factors.

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Section: Discussionmentioning

confidence: 90%

Impaired kidney function is associated with lower quality of life among community-dwelling older adults

et al. 2020

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“…Due to the significance of disability and QOL research intensively investigated possible determinants regarding functional status and QOL, in order to promote prevention and rehabilitation schemes [54][55][56][57][58]. Depending on the socio-cultural context frequently observed determinants of disability and QOL are: social demographics, housing situation, socioeconomical status, psychosocial characteristics (social participation, social support), health behaviour, relevant comorbidities, self-rated health as well as the reciprocal interaction of disability and QOL [20,54,[58][59][60][61][62][63][64][65][66]. Regarding the aforementioned determinants, older age represents a risk factor regarding disability [67,68], while its influence on QOL remains controversial [47,49,69].…”

Section: Introductionmentioning

confidence: 99%

Multivariate analysis of independent determinants of ADL/IADL and quality of life in the elderly

et al. 2022

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Background This study evaluated the determinants of disability and quality of life in elderly people who participated at the multi-centred RubiN project (Regional ununterbrochen betreut im Netz) in Germany. Methods Baseline data of the subjects aged 70 years and older of the RubiN project were used and only subjects with complete data sets were considered for the ensuing analysis (complete case analysis (CCA)). Disability was examined using the concepts of ADL (activities of daily living) and IADL (instrumental activities of daily living). Subjects exhibiting one or more deficiencies in ADL respectively IADL were considered as ADL respectively IADL disabled. Quality of life was assessed using the WHOQOL-BREF and the WHOQOL-OLD. Applying multivariate analysis, sociodemographic factors, psychosocial characteristics as well as the functional, nutritional and cognitive status were explored as potential determinants of disability and quality of life in the elderly. Results One thousand three hundred seventy-five subjects from the RubiN project exhibited data completeness regarding baseline data. ADL and IADL disability were both associated with the respective other construct of disability, sex, a reduced cognitive and functional status as well as domains of the WHOQOL-BREF. Furthermore, ADL disability was related to social participation, while IADL disability was linked to age, education and social support. Sex, ADL and IADL disability, income, social support and social participation as well as the functional status were predictors of the domain ‘Physical Health’ (WHOQOL-BREF). The facet ‘Social Participation’ (WHOQOL-OLD) was affected by both ADL and IADL disability, income, social participation, the nutritional and also the functional status. Conclusions Several potential determinants of disability and quality of life were identified and confirmed in this study. Attention should be drawn to prevention schemes as many of these determinants appear to be at least partly modifiable.

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“…[27][28][29] Moreover, this study findings align with other studies, which discovered that patients with KOA from North, Central, and South America, Europe, Asia, and Brazil significantly impacted their quality of life. [4,18,[30][31][32] These patients characteristics, such as gender, body weight, physical activity, mental health, pain, non-optimal nutrition, and education, impact their quality of life. The results of this study also corroborate those of a recent study that found KOA is strongly linked to worsening mental health and HRQoL in middle-aged (50 years or old) and older men and women.…”

Section: Discussionmentioning

confidence: 99%

A conceptual model of factors associated with health-related quality of life in men and women with knee osteoarthritis in Riyadh, Saudi Arabia: A multicenter cross-sectional study

et al. 2023

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This study used a conceptual model to examine the factors influencing physical, mental, and overall health-related quality of life (HRQoL) in women and men aged 45 and older with knee osteoarthritis (KOA) in Saudi Arabia. In this multicenter cross-sectional study, we randomly included 356 individuals aged 45 years or above with doctor-confirmed KOA from the orthopedic and physiotherapy departments of the 5 tertiary hospitals in Riyadh, Saudi Arabia, between March 2016 and March 2017. We split all participants into men (n = 146) and women (n = 210) based on gender. A conceptual model was developed using the HRQoL influential potential factors, such as age, sex, education, occupation, and way of eating (sociodemographic), and clinical factors, such as osteoarthritis knee and its severity, duration, pain, and body mass index. The 36-item short form health survey and its subscales of the physical composite scale and mental composite scale were used to evaluate overall HRQoL, physical, and mental health, respectively. We used unadjusted multiple linear regression analyses to investigate the associations between gender-specific potential factors and HRQoL outcomes. Women and men aged between 60 and 64 years were more strongly associated significantly with less physical composite scale score by −3.17, (standard error [SE] = 1.71, P = .021) and −3.18 (SE = 1.69, P = .023) respectively, followed by the primary school or less education by −3.40 (SE = 1.27, P = .0002), severe KOA of −8.94 (SE = 0.99, P < .001), eating on the floor bending the knee of −3.93 (SE = 1.63, P = .042), and pain of −2.39 (SE = 0.26, P < .0001). Women and men with primary school or less education significantly had low mental composite scale and 36-item short form health survey scores of −3.07 (SE = 1.22, P = .041) and −3.23 (SE = 0.99, P = .018), respectively, followed by severe KOA of −4.07 (SE = 1.22, P = .001) and −6.50 (SE = 0.83, P < .0001) and eating on the floor, extending the knee at −3.35 (SE = 1.74, P = .043). Risk factors like age, education, pain, body mass index, and severe KOA are linked to poor physical, mental, and overall HRQoL among women and men in Saudi Arabia.

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Factors associated with health‐related quality of life in community‐dwelling elderly people in China

Cited by 10 publications

References 28 publications

Impaired kidney function is associated with lower quality of life among community-dwelling older adults

Impaired kidney function is associated with lower quality of life among community-dwelling older adults

Multivariate analysis of independent determinants of ADL/IADL and quality of life in the elderly

A conceptual model of factors associated with health-related quality of life in men and women with knee osteoarthritis in Riyadh, Saudi Arabia: A multicenter cross-sectional study

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