Factors associated with health-related quality of life among injection drug users at methadone clinics in Taipei, Taiwan

Yen, Yung‐Feng; Chou, Pesus; Lin, Yu Shiuan; Deng, Chung Yeh

doi:10.1016/j.jcma.2015.01.001

Cited by 18 publications

(27 citation statements)

References 34 publications

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“…Univariate analysis showed that patients with no treatment terminations had higher SF-36v2PCS scores than those with repeat terminations, indicating that consecutive MMT improved physical HRQoL [15,19]. This finding supports our first hypothesis: Patients with repeat terminations had poorer HRQoL than those with no terminations.…”

Section: Discussionsupporting

confidence: 56%

Bidirectional relationships between retention and health-related quality of life in Chinese mainland patients receiving methadone maintenance treatment

Zhou

Wang

et al. 2017

PLoS ONE

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This study aimed to explore the bidirectional relationships between retention and health-related quality of life (HRQoL) in patients from mainland China receiving methadone maintenance treatment (MMT). This prospective cohort study recruited 1,212 eligible MMT patients from the two largest MMT clinics (one privately and another publicly funded) in Xi’an. This study started in March 2012 with a 2-year follow-up until March 2014. Retention was assessed by repeated terminations, past treatment duration, premature terminations, and follow-up treatment duration. HRQoL was evaluated using the Chinese (simple) short-form 36 health survey version 2 (SF-36v2) and the quality of life scale for drug addicts (QOL-DAv2.0). Linear and Cox regression analyses were used to explore relationships between retention and HRQoL. A general linear model was used to further examine the global effect of past treatment duration on HRQoL. Multivariate analyses showed that repeated terminations had no significant impact on HRQoL scores in MMT patients; however, past treatment time (year) influenced the SF-36v2PCS (P = 0.004): treatment for ≥4 years showed a lower SF-36v2PCS score (regression coefficient: -2.39; 95% confidence interval [CI]: -3.80, -0.97; P = 0.001) than treatment for <1 year. In addition, patients with an SF-36v2PCS score > 49 (hazard ratio: 0.83; 95% CI: 0.69, 0.98; P = 0.03) were 17% less likely to terminate MMT than those with scores of ≤49. In conclusion, retention and HRQoL tended to have a bidirectional relationship, which should be considered in the development of retention and health-management programs for patients with MMT.

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Section: Discussionsupporting

confidence: 56%

Bidirectional relationships between retention and health-related quality of life in Chinese mainland patients receiving methadone maintenance treatment

Zhou

Wang

et al. 2017

PLoS ONE

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“…Cross-sectional research has reported a range of correlates of low quality of life in this population, including older age [2], lower educational level [3], unemployment [4], opioid overdose [5, 6], mental illness [5, 7–9], history of imprisonment [6, 10], insecure housing [10], being assaulted [4, 10], younger age at first injection [4], not receiving opioid substitution therapy [6] and alcohol and other substance use [3, 11, 12]. However, most previous research uses quality of life measures that focus on physical health, commonly measured through a symptom checklist, which is only one component of quality of life [13, 14].…”

Section: Introductionmentioning

confidence: 99%

Longitudinal changes in personal wellbeing in a cohort of people who inject drugs

et al. 2017

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AimsTo determine whether the self-reported personal wellbeing of a cohort of people who inject drugs (PWID) changes over time, and to identify longitudinal correlates of change.MethodsWe used Personal Wellbeing Index (PWI) scores reported between April 2008 and February 2015 by 757 PWID (66% male) enrolled in the Melbourne Injecting Drug Use Cohort Study (2,862 interviews; up to seven follow-up waves). A mixed-effects model was used to identify correlations between changes in temporal variables and changes in individual PWI scores while controlling for demographic variables.ResultsThe cohort’s mean PWI score did not significantly differ over time (between 54.4/100 and 56.7/100 across the first four interview waves), and was 25–28% lower than general Australian population scores (76.0/100). However, there were large variations in individuals’ PWI scores between interviews. Increased psychological distress, moving into unstable accommodation, reporting intentional overdose in the past 12 months and being the victim of assault in the past six months were associated with declines in PWI scores.ConclusionsParticipants experienced substantially lower levels of personal wellbeing than the general Australian population, influenced by experiences of psychological distress, assault, overdose and harms related to low socioeconomic status. The results of this study suggest a need to ensure referral to appropriate housing and health support services for PWID.

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“…Health-related quality of life (HRQoL) is a multifactorial construct describing individuals’ perceptions of their own physical, psychological, and social functioning [1]. It has been regarded as a valuable patient-reported outcome in evaluations of therapeutic effectiveness and health for patients undergoing methadone maintenance treatment (MMT) [2].…”

Section: Introductionmentioning

confidence: 99%

Relationships between received and perceived social support and health-related quality of life among patients receiving methadone maintenance treatment in Mainland China

Zhou

Wei

et al. 2017

Subst Abuse Treat Prev Policy

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BackgroundSocial support has been considered one of the most important factors of health-related quality of life (HRQoL) evaluations among different populations; however, few studies have explored the relationships of both received and perceived social support to HRQoL among patients undergoing methadone maintenance treatment (MMT). Thus, the purpose of this cross-sectional study was to clarify these relationships.MethodsParticipants were patients admitted at the two largest privately and publicly funded MMT clinics in Xi’an. The main explanatory variable was social support, both received (i.e., social network support and professional support services) and perceived (Multidimensional Scale of Perceived Social Support). The outcome was HRQoL, which was evaluated using the Short-Form 36 Health Survey version 2 (SF-36v2) and the Quality of Life Scale for Drug Addicts (QOL-DAv2.0). We carried out independent samples t-tests and multiple linear regression analysis to examine the relationships between received and perceived social support and HRQoL.ResultsThe study findings revealed that patients with good social support had significantly higher scores on the SF-36v2 and QOL-DAv2.0 (p < 0.05). After controlling for individual characteristics, the significant factors predicting HRQoL were good family relationships, usually communicating with others, a convenient service time, appropriate treatment charges, and good perceived social support (p < 0.05).ConclusionsOur results suggest that received and perceived social support influences HRQoL among individuals receiving MMT. Thus, these variables should be considered during health management efforts and interventions directed at this patient population.

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Factors associated with health-related quality of life among injection drug users at methadone clinics in Taipei, Taiwan

Cited by 18 publications

References 34 publications

Bidirectional relationships between retention and health-related quality of life in Chinese mainland patients receiving methadone maintenance treatment

Bidirectional relationships between retention and health-related quality of life in Chinese mainland patients receiving methadone maintenance treatment

Longitudinal changes in personal wellbeing in a cohort of people who inject drugs

Relationships between received and perceived social support and health-related quality of life among patients receiving methadone maintenance treatment in Mainland China

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