Factors associated with in-hospital recurrence of intestinal intussusception in children

Abstract

Background A minority of children experience in-hospital recurrence of intestinal intussusception after treatment. This study investigated the factors associated with in-hospital recurrence of intussusception in pediatric patients in China. Methods This retrospective study included patients aged 0–18 years-old with intestinal intussusception treated at Hainan Women and Children’s Medical Center between January 2019 and December 2019. Demographic and clinical characteristics were extracted from the medical records. Factors associated with in-hospital recurrence of intussusception were identified by logistic regression analysis. Results The analysis included 624 children (400 boys) with a median age of 1.8 years (range, 2 months and 6 days to 9 years). Seventy-three children (11.7%) had in-hospital recurrence of intussusception after successful reduction with air enema. Multivariate logistic regression analysis identified age > 1 year-old (odds ratio [OR]: 7.65; 95% confidence interval [95%CI]: 2.70–21.71; P < 0.001), secondary intestinal intussusception (OR: 14.40; 95%CI: 4.31–48.14; P < 0.001) and mesenteric lymph node enlargement (OR: 1.90; 95%CI: 1.13–3.18; P = 0.015) as factors independently associated with in-hospital recurrence of intussusception. Conclusions Age > 1 year-old, secondary intussusception and mesenteric lymph node enlargement were independently associated with increased odds of in-hospital recurrence of intussusception after successful reduction with air enema.

Developing a Nomogram for Predicting Surgical Intervention in Pediatric Intussusception After Pneumatic Reduction: A Multicenter Study from China

“… 6 In clinical practice, the main treatment methods are pneumatic reduction under X-ray fluoroscopy and water enema under ultrasound guidance. 7 However, the high cost of disposable water enema equipment poses a significant economic burden in developing countries, limiting its clinical application in China. 8 , 9 Consequently, most medical institutions still rely on air enema as the primary technique, which has a high success rate, good prognosis, and few complications.…”