Factors Associated With Laser Trabeculoplasty Response Duration: Analysis of a Large Clinical Database (IRIS Registry)

Abstract

Supplemental Digital Content is available in the text.

Selective Laser Trabeculoplasty

“…2,[25][26][27][28][29] In patients with IOP controlled on multiple medications who may have difficulty with adherence to drops or experience adverse side effects from drops, SLT has been shown to be effective in reducing medication burden while maintaining IOP control. [30][31][32][33] Although SLT efficacy has primarily been studied in POAG and ocular hypertension, various secondary OAG subtypes have shown favorable responses. SLT can be effective in steroid-induced glaucoma.…”

“…33 Eyes that were not on any medications at baseline remained medication-free for a mean of 317.6 days after treatment. 33 A retrospective study by Ansari 55 found that SLT had a 10-year success rate of 72% (success defined as a 20% reduction of IOP from the baseline and IOP <19 mm Hg) among 108 treatment-naïve eyes of 54 patients with mild POAG. The study cohort had minimal visual field progression and no need for glaucoma surgery over 10 years.…”

“…In patients with IOP controlled on multiple medications who may have difficulty with adherence to drops or experience adverse side effects from drops, SLT has been shown to be effective in reducing medication burden while maintaining IOP control 30–33 …”

“…Approximately 75% of nonresponders with at least one medication at baseline, regardless of pretreatment IOP, reduced at least one medication posttreatment, justifying the use of SLT to reduce medication burden in medically controlled patients 32 . Using the same data set, the authors performed a survival analysis of responders and noted younger age and uveitis to be independent risk factors for failures, whereas glaucoma severity and surgeon experience seemed to confer no effect on overall survival 33 . Eyes that were not on any medications at baseline remained medication-free for a mean of 317.6 days after treatment 33 …”

“…Using the same data set, the authors performed a survival analysis of responders and noted younger age and uveitis to be independent risk factors for failures, whereas glaucoma severity and surgeon experience seemed to confer no effect on overall survival 33 . Eyes that were not on any medications at baseline remained medication-free for a mean of 317.6 days after treatment 33 …”