Factors Associated with Long-Term Benzodiazepine Use Among Elderly Women and Men in Quebec

Fortin, Dany; Préville, Michel; Ducharme, Claire; Hébert, Réjean; Trottier, Lise; Grégoire, Jean‐Pierre; Allard, Jacques; Bérard, Anick

doi:10.1300/j074v19n03_04

Cited by 13 publications

(17 citation statements)

References 21 publications

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“…Sex was investigated as a covariate, because of the preponderance of women in benzodiazepine use [23, 31, 42, 55, 57, 58], and in the prevalences of depression and anxiety disorders [32, 59]. …”

Section: Methodsmentioning

confidence: 99%

Ten-year trends in benzodiazepine use in the Dutch population

Sonnenberg¹,

Bierman²,

Deeg³

et al. 2011

Soc Psychiatry Psychiatr Epidemiol

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BackgroundIn the past decades knowledge on adequate treatment of affective disorders and awareness of the negative consequences of long-term benzodiazepine use increased. Therefore, a decrease in benzodiazepine use is expected, particularly in prolonged use. The aim of this study was to assess time trends in benzodiazepine use.Methods and materialData from the Longitudinal Aging Study Amsterdam (LASA) were used to investigate trends in benzodiazepine use between 1992 and 2002 in two population-based samples aged 55–64 years. Differences between the two samples with respect to benzodiazepine use and to sociodemographic, physical health and mental health characteristics were described and tested with chi-square tests and logistic regression analyses.ResultsBenzodiazepine use remained stable over 10 years, with 7.8% in LASA-1 (n = 874) and 7.9% in LASA-2 (n = 919) (p = 0.90) with a persisting preponderance in women and in people with low education, low income, chronic physical diseases, functional limitations, cognitive impairment, depression, anxiety complaints, sleep problems and when using antidepressants. Long-term use remained high with 70% in 1992 and 80% in 2002 of total benzodiazepine use.ConclusionIn the Dutch population aged 55–64, overall benzodiazepine use remained stable from 1992 to 2002, with a high proportion of long-term users, despite the effort to reduce benzodiazepine use and the renewal of the guidelines. More effort should be made to decrease prolonged benzodiazepine use in this middle-aged group, because of the increasing risks with ageing.

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Section: Methodsmentioning

confidence: 99%

Ten-year trends in benzodiazepine use in the Dutch population

Sonnenberg¹,

Bierman²,

Deeg³

et al. 2011

Soc Psychiatry Psychiatr Epidemiol

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“…About half (51%, n = 21) of the 41 included studies were from Europe. Nine studies came from Canada [27][28][29][30][31][32][33][34][35][36], making it a country with the highest number of published studies.…”

Section: Description Of the Included Studiesmentioning

confidence: 99%

“…1). Fifteen studies focused on aged people (in most of the included studies defined as 65 years old) who used BZDs or Z-drug for long-term [28][29][30]32,33,36,41,49,52,[57][58][59]63]. Only one study was conducted among adolescents < 19 years [51].…”

Section: Description Of the Included Studiesmentioning

confidence: 99%

Long-term use of benzodiazepines: Definitions, prevalence and usage patterns – a systematic review of register-based studies

et al. 2015

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Long-term BZD use is common and a clinical reality. Uniform definitions for "long-term", which is in line with population-based evidence, is needed to have more comparable results between studies. Our systematic review suggests that duration of BZD treatment over six months, the most common definition for long-term BZD use in the included studies. As also recommended previously, it is a useful starting point for further analyses on disadvantages but also potential advantages associated with long-term BZD use.

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“…Long‐term BZD use is associated with old age (Cunningham et al., ; Dag, ; Manthey et al., ; Veronese et al., ; Zandstra et al., ), female sex (Fortin et al., ; Jorm, Grayson, Creasey, Waite, & Broe, ), being divorced (Jorm et al., ) and in the lowest income quintile (Cunningham et al., ), history of BZD use (Dag, ; Manthey et al., ; Neutel, ), severe depressive (Cheng, Huang, Lin, & Shih, ; Luijendijk, Tiemeier, Hofman, Heeringa, & Stricker, ) and anxiety symptoms (Cheng et al., ; Manthey et al., ), length of illness (Veronese et al., ), psychiatric history (Zandstra et al., ), poor self‐perceived life satisfaction (Fourrier, Letenneur, Dartigues, Moore, & Begaud, ; Zandstra et al., ), poor physical health (Cheng et al., ; Cunningham et al., ; Luijendijk et al., ; Zandstra et al., ), and frequent contact with medical services (Jorm et al., ). Our data suggest that long‐term BZD use among patients with MDD is increased with age and is more frequent in patients who reported impairment in occupational functions.…”

Section: Discussionmentioning

confidence: 99%