Factors Associated with Medication Non-Adherence in Patients Suffering from Schizophrenia: A Cross-Sectional Study in a Universal Coverage Health-Care System

Dassa, D.; Boyer, Laurent; Benoît, Michel; Bourcet, Stéphane; Raymondet, P.; Bottaï, T.

doi:10.3109/00048674.2010.493503

Cited by 91 publications

(91 citation statements)

References 41 publications

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“…Type of antipsychotic drugs was not found to have statistical significance. Contrary to this study done in France indicated that Individuals prescribed atypical antipsychotic drugs were more likely to be adherent than those prescribed typical antipsychotics [21]. The possible reason can be since participant in the current study area had less availability of atypical antipsychotic over typical antipsychotics which resulting in taking their medication unless they developed extra pyramidal side effects which is difficult for patient to tolerate side effects.…”

Section: Discussioncontrasting

confidence: 50%

Prevalence of Antipsychotic Drug Non Adherence and Associated Factors Among Patients with Schizophrenia Attending at Amanuel Mental Specialized Hospital, Addis Ababa, Ethiopia: Institutional Based Cross Sectional Study

Girma¹,

Abdisa²,

Fikadu³

2017

Health Sci J

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Background: Drug non adherence is a problem in all areas of medicine, and psychiatry is no exception. Mental health institutions are widely over burdened by mental ill patient who sought frequent treatment as a result of drug non adherence. Although patients suffering from psychiatric disorders are the most likely not to adhere to treatment than any other physical illness; there was no study done to determine the prevalence and associated factors of antipsychotic drug non adherence among schizophrenia patients in Ethiopia. So this study was aimed to assess the prevalence and associated factors of antipsychotic drug non-adherence among patients with schizophrenia attending at Amanuel mental specialized hospital.

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Section: Discussioncontrasting

confidence: 50%

Prevalence of Antipsychotic Drug Non Adherence and Associated Factors Among Patients with Schizophrenia Attending at Amanuel Mental Specialized Hospital, Addis Ababa, Ethiopia: Institutional Based Cross Sectional Study

Girma¹,

Abdisa²,

Fikadu³

2017

Health Sci J

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“…Abrupt withdrawal of some psychiatric medication, such as selective-serotonin reuptake inhibitors and antipsychotics, may lead to withdrawal symptoms and worsening of symptoms, thus increasing the risk of relapse, suicidal tendencies and re-hospitalisation 7 8…”

Section: Discussionmentioning

confidence: 99%

Pharmacist intervention in a psychiatric setting

et al. 2015

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ObjectiveInadequate adherence in psychiatric patients is known to lead to relapse and re-admission. The aim of this study was to introduce and evaluate a pharmacist intervention directed at psychiatric ‘on leave’ patients and their family members. At Mount Carmel Hospital, patients are sent home ‘on leave’ but given follow-up appointments. During each appointment visit, a decision is made either to send the patient back home (‘on leave’) or keep them in hospital as an in-patient.MethodsTwenty ‘on leave’ psychiatric patients who self-administer their medication and 20 family members were interviewed before the pharmacist intervention using the Medication Adherence Questionnaire; the medication adherence questions were not applicable to family members. The intervention consisting of explanation and distribution of personalised medication charts was then administered. Between 2 and 4 weeks after the pharmacist intervention, all participants (n=40) were re-interviewed using question 9 from the same questionnaire and the Medication Chart Evaluation Form.ResultsThe mean percentage score for knowledge concerning dosage regimen was higher after the intervention (98.0%) than before (89.0%) (p=0.001). The mean percentage score for knowledge concerning medicine type/indication was also higher after the intervention (89.3%) than before (59.2%) (p∼0.000).ConclusionsThis study highlights the importance of the pharmacist's role as an educator. The medication chart helped the patients improve their medication awareness and knowledge, which increases medication adherence.

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“…A long DUP has been found to be associated with more severe positive and negative symptoms [10][11][12], longer length of first hospitalization [13], poorer remission status and higher risk of relapse and rehospitalisation [8,11,13,14]. Such negative outcomes can lead to further consequences, such as increased burden and expressed emotion in the family [15], reduced compliance to treatment [16,17], lower treatment response rates [18][19][20][21][22], increased risk of depression, suicide and self-harming behaviour [23][24][25], higher risk of violence, aggression and delinquent behaviour [26][27][28] and eventually greater impairment in general functioning, social functioning and quality of life [11,14,29,30].…”

Section: Clinical Relevance and Impact Of Delayed Treatmentmentioning

confidence: 99%

The Psychosis High-Risk State

Rutigliano¹,

Manalo²,

Fusar‐Poli

2016

Key Issues in Mental Health

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The disabling nature and costly impact of mental disorders, such as schizophrenia, can cause significant burden to both person and society. It is also indicated that the negative outcomes associated with psychosis may, in part, be due to the delayed detection and initiation of treatment. Preventative interventions in several arenas of medicine have advanced; however have only come to the fore in psychiatry in the last two decades. It was long-known that a preclinical phase preceded psychosis, now commonly termed as ultra high-risk (UHR) status.The advent of specialized early intervention services provided the cornerstone in taking a preventative and timely endeavor to maximize the chance of positive outcomes in psychosis.Despite the potential, the current state of the UHR concept lacks consensus in how at-risk individuals should be approached. This chapter aims to provide an overview of how preventative medicine can intersect with psychiatry by focusing on the psychosis high risk state. It describes the current criteria and screening procedures used to prospectively detect UHR individuals, as well as discussing the validity of these tools. Whilst advocating the benefits of focused interventions, this chapter also recognizes current challenges and the controversy that leaves the psychosis high risk state on fertile ground for wavering opinions.The chapter concludes with an exploration and discussion that proposes an improved conceptualization of the high risk state and how this can direct intervention, as well as suggesting future lines of research in this area.2

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Factors Associated with Medication Non-Adherence in Patients Suffering from Schizophrenia: A Cross-Sectional Study in a Universal Coverage Health-Care System

Cited by 91 publications

References 41 publications

Prevalence of Antipsychotic Drug Non Adherence and Associated Factors Among Patients with Schizophrenia Attending at Amanuel Mental Specialized Hospital, Addis Ababa, Ethiopia: Institutional Based Cross Sectional Study

Prevalence of Antipsychotic Drug Non Adherence and Associated Factors Among Patients with Schizophrenia Attending at Amanuel Mental Specialized Hospital, Addis Ababa, Ethiopia: Institutional Based Cross Sectional Study

Pharmacist intervention in a psychiatric setting

The Psychosis High-Risk State

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