Factors associated with mortality of TB/HIV co-infected patients in Ethiopia

Teklu, Alula M.; Nega, Abiy; Mamuye, Admasu Tenna; Sitotaw, Yohannes; Kassa, Desta; Mesfin, Getnet; Belayihun, Bekele; Medhin, Girmay; Yirdaw, Kesetebirhan Delele

doi:10.4314/ejhs.v27i1.4s

Cited by 39 publications

(33 citation statements)

References 21 publications

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“…However, studies have identified gender inequality, observing that women with low income and schooling, who had monogamous relationships throughout their lives, were at risk of a delayed diagnosis of HIV/AIDS [48]; this phenomenon was also observed in the USA, where female patients at risk of delayed HIV diagnosis were poorer, non-urban, and possibly exposed to HIV heterosexually [49], which may be associated with the findings of the present study. There is little evidence to explain this result regarding the gender difference from the individual perspective in terms of TB mortality, but the results may also be associated with a low CD4 count, not receiving antiretroviral therapy or undergoing cotrimoxazole prophylaxis therapy, being a female sex worker, being older, and being bedridden [50,51].…”

Section: Discussionmentioning

confidence: 99%

Survival time among patients who were diagnosed with tuberculosis, the precocious deaths and associated factors in southern Brazil

et al. 2021

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Background A diagnosis of tuberculosis (TB) does not mean that the disease will be treated successfully, since death may occur even among those who are known to the health services. Here, we aimed to analyze patient survival time from the diagnosis of TB to death, precocious deaths, and associated factors in southern Brazil. Methods We conducted a longitudinal study with patients who were diagnosed with TB and who died due to the disease between 2008 and 2015 in southern Brazil. The starting point for measuring survival time was the patient’s diagnosis date. Techniques for survival analysis were employed, including the Kaplan-Meier test and Cox’s regression. A mixed-effect model was applied for identifying the associated factors to precocious deaths. Hazard ratio (HR) and odds ratio (OR) with 95% confidence intervals (95% CI) were estimated. We defined p value <0.05 as statistically significant for all statistics applied. Results One hundred forty-six patients were included in the survival analysis, observing a median survival time of 23.5 days. We observed that alcoholism (HR=1.55, 95% CI=1.04-2.30) and being male (HR=6.49, 95% CI=1.03-2.68) were associated with death. The chance of precocious death within 60 days was 10.48 times greater than the chance of early death within 30 days. Conclusion Most of the deaths occurred within 2 months after the diagnosis, during the intensive phase of the treatment. The use of alcohol and gender were associated with death, revealing inequality between men and women. This study advanced knowledge regarding the vulnerability associated with mortality. These findings must be addressed to fill a gap in the care cascades for active TB and ensure equity in health.

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Section: Discussionmentioning

confidence: 99%

Survival time among patients who were diagnosed with tuberculosis, the precocious deaths and associated factors in southern Brazil

et al. 2021

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“…O predomínio de casos em pessoas do sexo masculino (76,6%) corroborou achados na literatura. (10)(11)(12)(13)(14)(15)(16)(17)(18)(19) Uma possível causa para o predomínio do sexo masculino refere-se ao aumento da notificação dos casos de aids entre este grupo e a baixa detecção e notificação da aids entre mulheres adultas no período de 2006 a 2017, exceto entre as mulheres idosas. (20) Uma Revisão Sistemática (RS) realizada em países de baixa renda revelou que outra possível razão é que os homens possuem uma prevalência mais alta de TB, pois retardam a procura por atendimento, permanecendo mais tempo infectados em relação às mulheres, o que se reflete no diagnóstico e tratamento oportuno.…”

Section: Discussionunclassified

Coinfecção tuberculose/HIV: perfil sociodemográfico e saúde de usuários de um centro especializado

Bastos

Taminato

Tancredi

et al. 2020

Acta Paulista De Enfermagem

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“…Diversos fatores extrínsecos têm dificultado o controle dessa enfermidade, dentre eles: aglomeração das populações urbanas, condições socioeconômicas desfavoráveis, migrações, aumento de casos de HIV e aumento de tuberculose multirresistente (TBMDR). Ademais, fatores intrínsecos, como o estado imunológico do indivíduo, ambiente que está inserido e a duração da exposição ao bacilo, também contribuem para a dificuldade de controle da doença (DING et al, 2017;TEKLU et al, 2017).…”

Section: Resultsunclassified

Distribuição Espacial Das Doenças Tropicais Negligenciadas Na Região Oeste Do Estado De São Paulo

Titosse¹,

Fonseca²,

Rodrigues³

et al. 2020

RCG

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Este artigo tem como objetivo caracterizar a incidência de doenças tropicais negligenciadas na região do oeste do estado de São Paulo entre 2007 e 2017. Trata-se de um estudo ecológico descritivo, com abordagem espaço-temporal, tendo por fonte de dados o Sistema de Agravos de Notificação (SINAN), o Instituto Brasileiro de Geografia e Estatística (IBGE). Foram elencadas 5 doenças: Dengue, Leishmaniose, Tuberculose, Hanseníase e Esquistossomose nos 45 municípios do Estado de São Paulo que compõe a Rede Regional de Assistência a Saúde (RRAS) de número 11, a RRAS11. A taxa de incidência das doenças elencadas em cada um dos 45 municípios da RRAS foi calculada através da razão entre o número de casos da doença e o número de habitantes no município em 2010. Através das taxas de incidência foi possível observar uma distribuição heterogênea dessas doenças nos 45 municípios em estudo, com maior incidência, em toda a região, de dengue e tuberculose. A comparação das taxas de incidência entre os diferentes municípios do Oeste Paulista nos permitiu identificar as populações em risco.

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Factors associated with mortality of TB/HIV co-infected patients in Ethiopia

Cited by 39 publications

References 21 publications

Survival time among patients who were diagnosed with tuberculosis, the precocious deaths and associated factors in southern Brazil

Survival time among patients who were diagnosed with tuberculosis, the precocious deaths and associated factors in southern Brazil

Coinfecção tuberculose/HIV: perfil sociodemográfico e saúde de usuários de um centro especializado

Distribuição Espacial Das Doenças Tropicais Negligenciadas Na Região Oeste Do Estado De São Paulo

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