Factors Associated With New-Onset Depression After Stroke

Abstract

To better identify stroke survivors at risk for depression who may benefit from early prevention through targeted strategies in the acute-subacute poststroke period, we examined 118 Framingham Heart Study stroke survivors with longitudinal prestroke depression assessments. Among those who developed poststroke depression, most lacked a history of depressive symptoms five years prior to their stroke. Women, advanced age, and prestroke factors (smoking and functional dependence) were associated with new-onset depression poststroke. These findings suggest fully characterizing and accounting for prestroke factors, including psychosocial and behavioral determinants, may inform the predictive modeling needed to determine whether targeted preventive trials early in stroke recovery will improve stroke outcomes.

Effect of intravenous alteplase on post‐stroke depression in the WAKE UP trial

“…Lesion volume [32] has been identified as a predictor of PSD [33] and was also associated with PSD in our analysis. Recurrently named predictors of PSD include higher disability after stroke, history of depression, low social support, lower education and cognitive impairment [22,27,31,34] of which history of depression was supported by this study. Additionally, higher mRS was associated with higher BDI score, as shown previously [13].…”

Особенности Биоэлектрической Активности Мозга У Перенесших Инсульт Пациентов С Тревожно-Депрессивными Расстройствами

“…Известно, что инсульт сопряжен с развитием тяжелых форм тревожно-депрессивных расстройств [18,13,6], утяжеляющей состояние пациента, сводя на нет результаты различных методов лечения и реабилитации. Однако исследований, посвященных подробному анализу результатов ЭЭГ у перенесших инсульт пациентов с психо-эмоциональными расстройствами, в открытых источниках нет.…”