Factors associated with prevalent hepatitis C: differences among young adult injection drug users in lower and upper Manhattan, New York City

doi:10.2105/ajph.91.1.23

Cited by 164 publications

(26 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…53,54 Specific behavioral patterns more prominent in this ethnic group include higher frequency and longer duration of drug use, nonaseptic techniques, and paraphernalia sharing. 53 Hispanic persons are also less likely than NHW persons to be tested for HCV, even in the presence of an acknowledged risk factor. 54 …”

Section: Resultsmentioning

confidence: 99%

Chronic Liver Disease in the Hispanic Population of the United States

Carrion

Ghanta

Carrasquillo

et al. 2011

Clinical Gastroenterology and Hepatology

View full text Add to dashboard Cite

Chronic liver disease is a major cause of morbidity and mortality among Hispanic people living in the United States. Environmental, genetic, and behavioral factors, as well as socioeconomic and health care disparities among this ethnic group have emerged as important public health concerns. We review the epidemiology, natural history, and response to therapy of chronic liver disease in Hispanic patients. The review covers nonalcoholic fatty liver disease, viral hepatitis B and C, coinfection of viral hepatitis with human immunodeficiency virus, alcoholic cirrhosis, hepatocellular carcinoma, autoimmune hepatitis, and primary biliary cirrhosis. For most of these disorders, the Hispanic population has a higher incidence and more aggressive pattern of disease and overall worse treatment outcomes than in the non-Hispanic white population. Clinicians should be aware of these differences in caring for Hispanic patients with chronic liver disease.

show abstract

Section: Resultsmentioning

confidence: 99%

Chronic Liver Disease in the Hispanic Population of the United States

Carrion

Ghanta

Carrasquillo

et al. 2011

Clinical Gastroenterology and Hepatology

View full text Add to dashboard Cite

show abstract

“…The robust association between sharing of injection equipment and infection is a common finding, 34–36 as is the increase in antibody prevalence with years of drug use. 37–40 Among PWID who have HIV infection, the prevalence of HCV is typically high - for example, approximately 80% of PWID living with HIV in the United States are HCV antibody positive. 41 People with a history of arrest are likely to have more exposure to carceral settings, environments that typically have an elevated prevalence of HCV.…”

Section: Discussionmentioning

confidence: 99%

Prevalence and predictors of HCV among a cohort of opioid treatment patients in Dar es Salaam, Tanzania

Lambdin

Lorvick

Mbwambo

et al. 2017

International Journal of Drug Policy

View full text Add to dashboard Cite

Background. The government of Tanzania launched an opioid treatment program (OTP), using methadone, in Dar es Salaam in February of 2011. Hepatitis C virus (HCV) is a leading cause of morbidity and mortality globally, especially among people who inject drugs (PWID). We conducted a cross-sectional study among PWID engaged in OTP in Dar es Salaam to describe the prevalence and predictors of HCV antibody serostatus. Methods. Routine programmatic data on patients enrolled in Muhimbili National Hospital’s OTP clinic from February 2011 to January 2013 were utilized. Multivariable Poisson regression was used to examine factors associated with HCV antibody serostatus. Results. A total of 630 PWID enrolled into the OTP clinic during the study period, seven percent of which were women. The overall seroprevalence of HCV antibody was 57% (95% Confidence interval: 53%-61%). In adjusted analysis, methadone patients who used heroin for 5-10 years (adjusted prevalence ratio; aPR=1.41; 95% CI: 1.10-1.81) and >10 years (aPR=1.48; 95% CI: 1.17-1.88) were more likely to be HCV antibody positive, compared to patients who used heroin for < 5 years. Patients who reported sharing needles or other equipment at their last injection (aPR=1.20; 95% CI: 1.01-1.41; p=0.022), being arrested (aPR=1.20; 95% CI: 1.04-1.40; p=0.012) and who were HIV-positive (aPR=1.84; 95% CI: 1.56-2.16; p<0.001) were also more likely to be HCV antibody positive than their counterparts. Conclusion. Our observed HCV antibody prevalence among PWID engaged in OTP is higher than previously reported estimates in Dar es Salaam. Predictors of HCV antibody serostatus in this sample were similar to those found among PWID in many other settings. Integrating HCV care and treatment into OTP clinics should be considered, leveraging lessons learned from the integration of HIV services into OTP. Global efforts to develop HCV care and treatment programs in low and middle-income countries are critical, especially among PWID who have a high burden of HCV.

show abstract

“…The present study used cross-sectional survey-based data and was part of a larger study concerned with determinants of HIV and concurrent HCV (Diaz et al, 2001a,b). Participants were recruited from the Central Harlem and South Bronx neighborhoods of New York City (n = 1,184) in November of 2001 through February of 2004.…”

Section: Methodsmentioning

confidence: 99%

“…These locations were then chosen as sites of recruitment. Recruitment was conducted through targeted sampling with street outreach techniques (Diaz et al, 2001a,b; Ompad et al, 2005). Study recruiters were residents of the same neighborhoods from which participants were recruited.…”

Section: Methodsmentioning

confidence: 99%

Characteristics of drug users who witness many overdoses: Implications for overdose prevention

Bohnert

Tracy

Galea

2012

Drug and Alcohol Dependence

View full text Add to dashboard Cite

Background Programs to improve response of drug users when witnessing an overdose can reduce overdose mortality. Characteristics of drug users may be associated with the number of overdoses ever witnessed. This information could inform overdose prevention programs. Methods Participants in New York City, who were age 18 and older with heroin and/or with cocaine use in the past two months, were administered structured interviews (n = 1,184). Survey topics included overdose response, drug use behavior, treatment history, and demographic information. Results In a multivariable negative binomial regression model, those persons who are male (IRR [Incidence Rate Ratio] = 1.7, CI [95% Confidence Interval] = 1.4,2.2), have experienced homelessness (IRR = 1.9, CI= 1.4,2.6), have used heroin (IRR = 2.0, CI = 1.3,3.2), have overdosed themselves (IRR = 1.9, CI = 1.6,2.4), and have attended Narcotics Anonymous (IRR = 1.3, CI = 1.1,1.6) witnessed a greater count of overdoses in their lifetime. Those persons who have witnessed more overdoses were less likely to have sought medical assistance (OR [Odds Ratio] = 0.7) and more likely to report counter-productive or ineffective actions (ORs between 1.9 and 2.4) at the last overdose they witnessed compared to persons who had only ever witnessed one or two overdoses. Conclusions Persons at high risk for overdose are likely to witness more overdoses. Persons who had witnessed more overdoses were more likely to report taking ineffective action at the last overdose witnessed; individuals who have witnessed many overdoses are likely key targets of overdose response training.

show abstract

Factors associated with prevalent hepatitis C: differences among young adult injection drug users in lower and upper Manhattan, New York City

Cited by 164 publications

References 34 publications

Chronic Liver Disease in the Hispanic Population of the United States

Chronic Liver Disease in the Hispanic Population of the United States

Prevalence and predictors of HCV among a cohort of opioid treatment patients in Dar es Salaam, Tanzania

Characteristics of drug users who witness many overdoses: Implications for overdose prevention

Contact Info

Product

Resources

About