Factors associated with reported food allergy tolerance among US children

Gupta, Ruchi S.; Lau, Claudia H.; Sita, Elizabeth E.; Smith, Bridget; Greenhawt, Matthew

doi:10.1016/j.anai.2013.06.026

Cited by 45 publications

(21 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Our implemented definition requiring diagnostic evaluation and EpiPen prescription following healthcare provider evaluation may in fact represent more rigor than real-world practice, where 30% of reported food allergy is not diagnosed by a physician, and 23% is not evaluated by diagnostic testing. 57 We recognize the limitation that subjects sensitized to >1 food allergen and prescribed EpiPen may have been classified as having >1 food allergy when they may have had only one. While we could corroborate our definition for peanut allergy with our specific questions targeting convincing IgE-mediated symptoms that would characterize a peanut allergic reaction, we did not have analogous questions targeting reaction symptoms to milk, wheat, egg, and soy.…”

Section: Discussionmentioning

confidence: 99%

Peanut, Milk, and Wheat Intake During Pregnancy Is Associated With Reduced Allergy and Asthma In Children

Bunyavanich

Rifas‐Shiman

Platts‐Mills

et al. 2014

Journal of Allergy and Clinical Immunology

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Peanut, Milk, and Wheat Intake During Pregnancy Is Associated With Reduced Allergy and Asthma In Children

Bunyavanich

Rifas‐Shiman

Platts‐Mills

et al. 2014

Journal of Allergy and Clinical Immunology

View full text Add to dashboard Cite

show abstract

“…The prevalence rates of paediatric FRS [12] and FA [13] appear to be rising. Although many children outgrow reactions to food [14] including FA [5, 15] by school age, some children experience persistence through adolescence [2, 7]. Amongst adolescents, FA, but also FRS without known background mechanisms, are associated with poorer health-related quality of life compared to healthy controls [16, 17].…”

Section: Introductionmentioning

confidence: 99%

Food-Related Symptoms and Food Allergy in Swedish Children from Early Life to Adolescence

et al. 2016

View full text Add to dashboard Cite

BackgroundRisk factors for persistence of food-related symptoms (FRS) and food allergy (FA) from early life to adolescence are incompletely understood. The aim of this study was to identify risk factors for FRS and FA in adolescence amongst children with FRS or FA in the first four years of life (early life).MethodsIn children enrolled in a Swedish birth cohort and followed to 16 years (n = 2572), we defined children with early life FRS in the absence of FA, and FA. Corresponding phenotypes were defined at 16 years. Associations between potential risk factors at 4 years and FRS and FA at 16 years were investigated using logistic regression.ResultsEarly life FRS and FA prevalences were 12.2% and 6.8%, respectively. Amongst children with early life FRS, 35.7% had FRS or FA at 16 years, whereas 74.3% of the children with early life FA had FA at 16 years. For each of the early life phenotypes, parental allergy, early life allergic multimorbidity, early life reactions to peanuts/tree nuts and IgE reactivity at 4 years were statistically significantly associated with FRS or FA at 16 years. In contrast, male sex was associated with an increased risk of FA at 16 years among children with early life FA only.ConclusionsIn early life, food-related symptoms are twice as common as food allergy. Unlike food allergy, food-related symptoms often remit by adolescence. Yet, these phenotypes have many common risk factors for persistence to adolescence.

show abstract

“…In a study by Gupta and colleagues, the total frequency of tolerance acquisition was 26.6% at a mean age of 5 years, with higher frequency of tolerance acquisition for milk, egg and soy allergy (41, 40 and 36%, respectively). The probability of outgrowing the allergy is associated with a history of mild reactions, allergy to only one food, atopic dermatitis and lower specific IgE levels [24]. Patients who had experienced their allergic reactions later in life, were those with lower probability to outgrowing their allergy.…”

Section: The Goal: Tolerance or Desensitization?mentioning

confidence: 99%

Immunotherapy for Food Allergies: A Myth or a Reality?

Praticò

Leonardi

2015

Immunotherapy

View full text Add to dashboard Cite

Food allergy is a worldwide issue, with an estimated prevalence of 2-10%. An effective treatment is not available for people affected and the only management is the avoidance of the allergen. Oral immunotherapy and sublingual immunotherapy have been tested by several authors, in particular for milk, egg and peanuts allergy, with significant results in term of desensitization induction. The achievement of tolerance is by the contrary doubtful, with different results obtained. In this review, we reviewed protocols of oral and sublingual immunotherapy for food allergy published in literature, mainly against milk, egg and peanut. At present, immunotherapy does not represent the gold standard in the treatment of food allergy, even if it can desensitize patients.

show abstract

Factors associated with reported food allergy tolerance among US children

Cited by 45 publications

References 25 publications

Peanut, Milk, and Wheat Intake During Pregnancy Is Associated With Reduced Allergy and Asthma In Children

Peanut, Milk, and Wheat Intake During Pregnancy Is Associated With Reduced Allergy and Asthma In Children

Food-Related Symptoms and Food Allergy in Swedish Children from Early Life to Adolescence

Immunotherapy for Food Allergies: A Myth or a Reality?

Contact Info

Product

Resources

About