Factors associated with reversals of COVID-19 vaccination willingness: Results from two longitudinal, national surveys in Japan 2021-2022

Ghaznavi, Cyrus; Yoneoka, Daisuke; Kawashima, Takayuki; Eguchi, Akifumi; Murakami, Michio; Gilmour, Stuart; Kaneko, Satoshi; Kunishima, Hiroyuki; Naito, Wataru; Sakamoto, Haruka; Maruyama-Sakurai, Keiko; Takahashi, Arata; Takayama, Yoshihiro; Tanoue, Yuta; Yamamoto, Yoshiko; Yasutaka, Tetsuo; Matsubara, Hiroaki; Nomura, Shuhei

doi:10.1016/j.lanwpc.2022.100540

Cited by 17 publications

(14 citation statements)

References 26 publications

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“…This contrasts with other studies that reported higher vaccine willingness with HCWs with underlying diseases or conditions 53,54 . It may be because the influence of co‐morbidities and prior COVID‐19 diagnosis on vaccine willingness could vary by region, depending on factors such as local healthcare infrastructure and public health messaging 55,56 …”

Section: Discussionmentioning

confidence: 76%

“… 53 , 54 It may be because the influence of co‐morbidities and prior COVID‐19 diagnosis on vaccine willingness could vary by region, depending on factors such as local healthcare infrastructure and public health messaging. 55 , 56 …”

Section: Discussionmentioning

confidence: 99%

“…53,54 It may be because the influence of co-morbidities and prior COVID-19 diagnosis on vaccine willingness could vary by region, depending on factors such as local healthcare infrastructure and public health messaging. 55,56 HCWs with less than a high school education had a higher vaccination coverage rate, indicating that a larger proportion of them had received at least one dose of the COVID-19 vaccine. It may be because people with low educational attainment know less about vaccines and worry less about safety.…”

Section: Contextual Influencementioning

confidence: 99%

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Vaccination willingness, vaccine hesitancy, and estimated coverage of SARS‐CoV‐2 vaccine among healthcare workers in Tanzania: A call for action

Kessy,

Wei,

Zhou

et al. 2023

Immunity Inflam & Disease

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BackgroundThe global COVID‐19 pandemic presented an immense obstacle to public health, with vaccination emerging as a crucial measure to curb transmission. This study aimed to evaluate the willingness, hesitancy, and coverage of SARS‐CoV‐2 vaccines among healthcare workers (HCWs) in Tanzania and reveal their concerns about SARS‐CoV‐2 vaccines and the reasons that might prevent them from getting vaccinated.MethodsWe conducted a cross‐sectional study using an anonymous online survey from October to November 2022. The multivariate logistic regression model explored the factors associated with SARS‐CoV‐2 vaccine willingness, hesitancy, and coverage.ResultsThe study included 560 HCWs, with the largest group being doctors (47.9%), followed by nurses (26.9%) and other HCWs (25.2%). A total of 70.5% of HCWs reported being vaccinated against SARS‐CoV‐2. The primary driver for SARS‐CoV‐2 vaccination was collective responsibility. A total of 81.4% of HCWs reported being willing to accept SARS‐CoV‐2 vaccines, while 62.5% of HCWs reported vaccine hesitancy. HCWs with higher educational qualifications were likelier to take the vaccine, while the respondents aged 18–30 years had the highest SARS‐CoV‐2 vaccination refusal (71.9%). We also investigated the role of HCWs as a source of information to promote COVID‐19 vaccine uptake. 79.4% of HCWs provided information and advice on SARS‐CoV‐2 vaccines.ConclusionTo increase vaccine acceptance among HCWs and the general population, targeted messaging is needed to deliver transparent information on vaccine safety, efficacy, and development.

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Section: Discussionmentioning

confidence: 76%

Section: Discussionmentioning

confidence: 99%

Section: Contextual Influencementioning

confidence: 99%

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Vaccination willingness, vaccine hesitancy, and estimated coverage of SARS‐CoV‐2 vaccine among healthcare workers in Tanzania: A call for action

Kessy,

Wei,

Zhou

et al. 2023

Immunity Inflam & Disease

View full text Add to dashboard Cite

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“…Second, Hong Kong Chinese older adults generally have lower educational attainment, which limits their ability to utilize health information for making a medical decision. There were only 11% of Hong Kong older adults obtained the tertiary education in 2021 48 , comparing to 47.1%, 32.1%, and 38.8%, respectively, in Japan, New Zealand and United Kingdom 49 where a higher willingness to take a COVID-19 vaccine was reported among older adults 9,50,51 . However, older age was positively associated with uptake of COVID-19 vaccine during P3, which may be attributable to the joint effect of intensive news media attention on deaths among older people due to COVID-19 and the implementation of door-to-door mobilization of vaccination for older people during this period 36 .…”

Section: Discussionmentioning

confidence: 90%

Dynamic predictors of vaccination uptake over two years of the COVID-19 vaccination campaign: lessons from Hong Kong

Liao,

YUAN,

et al. 2023

Preprint

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Promoting high vaccine uptake is a primary public health policy in mitigating the profound impact of COVID-19 pandemic. The evolution of the COVID-19 pandemic requires a dynamic evaluation of factors that are associated with COVID-19 vaccination uptake to inform a strategic plan on vaccination programmes. Using real-time population-based data that covered the two-year COVID-19 vaccine rollout in Hong Kong, this study was aimed to systematically investigate factors associated with the uptake of the primary and booster vaccine doses at different stages of the vaccination programme. We adopted a novel network approach to map the relationships of multilevel variables involving contextual factors (number of COVID-19 cases and deaths in the community, social vulnerability of the residential areas), COVID-19 risk perceptions, COVID-19 vaccine attitudes, mental and physical health variables as well as demographics with COVID-19 vaccination uptake over four key periods (P1-P4) of the COVID-19 vaccination campaign in Hong Kong. In total, 3523, 7056, 2580 and 2020 participants in P1, P2, P3 and P4 were included in our network analyses. A total of 983 participants’ verbal reasons for rejecting vaccination were also collected to supplement our understanding of factors associated with COVID-19 vaccination uptake. Our study sheds light on how to improve the effectiveness of future vaccination programmes against a pandemic. First, while people value vaccine safety more in the initial vaccination campaign, more attention is given to vaccine effectiveness at the later stage when evidence about vaccine safety has accumulated. Second, older people and those with chronic disease status are persistently the more vaccine-hesitant groups throughout vaccine rollout. This could be due to the contexts of insufficient decisional support from healthcare workers and family members for older people and their lower health literacy, a case in Hong Kong. However, more proactive and tailored strategies can successfully boost older peoples’ vaccination uptake, which is evidenced by the implementation of home-based vaccination campaign in Hong Kong when the most severe Omicron wave occurred. Third, disease risk has a weak association with vaccination uptake when vaccines become available, suggesting that people start to shift their attention to vaccine risk from disease risk after the vaccines become available particularly when the disease incidence in the community temporarily declines. Communication should focus on addressing concerns about vaccine safety and promoting awareness of disease resurgence risk. Fourth, more adoption of non-pharmaceutical preventive measures against COVID-19 is associated with lower uptake of the vaccine. Such pattern is more evident in P1, indicating that adoption of non-pharmaceutical preventive behaviours might give people the illusion that vaccination is not important and thereby demotivates their vaccination uptake. This is particularly the case in Hong Kong as the zero-COVID policy was implemented to contain disease spread before the Omicron wave occurred. Fifth, better-educated and married participants are likely to be the early innovation adopters who are more supportive of new vaccine-related policies and thereby should be one important target group for mobilizing other groups’ vaccination uptake. Furthermore, trust in government can be an important “bridging” factor to link other variables in the networks with vaccine confidence attitudes which subsequently closely correlate with vaccination uptake.

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“…To address the transition from a pandemic to an endemic, evidence-based optimization of diagnostic strategies should be considered in the global agenda. Many studies have assessed reasons for COVID-19 vaccination hesitancy [ 16 , 17 ]; however, research characterizing hesitancy and the factors influencing hesitancy to undergo RAT for COVID-19 is scarce. Our study aimed to understand the prevalence and correlates of hesitancy to undergo RAT for COVID-19 among adults uninfected with SARS-CoV-2 in mainland China.…”

Section: Introductionmentioning

confidence: 99%

Hesitancy to Undergo SARS-CoV-2 Rapid Antigen Testing in China: Nationwide Cross-sectional Study

Zou¹,

Lu²,

Fu³

et al. 2023

JMIR Public Health Surveill

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Background SARS-CoV-2 rapid antigen testing (RAT) could be a useful supplementary test to diagnose larger numbers of acute asymptomatic infections and alleviate the limitations of polymerase chain reaction testing. However, hesitancy to undergo SARS-CoV-2 RAT may compromise its implementation. Objective We aimed to understand the prevalence and correlates of hesitancy to undergo RAT among adults not infected with SARS-CoV-2 in mainland China. Methods A nationwide cross-sectional survey on hesitancy to undergo SARS-CoV-2 RAT was conducted among adults not infected with SARS-CoV-2 in mainland China between April 29, 2022, and May 10, 2022. Participants completed an online questionnaire that covered the following COVID-19–related factors: sociodemographic characteristics, experiences of COVID-19 restrictions and knowledge of COVID-19, and attitude toward COVID-19 and its screening. This study was a secondary analysis of data from the survey. We compared the characteristics of participants by hesitancy to undergo SARS-CoV-2 RAT. Thereafter, logistic regression with a sparse group minimax concave penalty was used to identify correlates of hesitancy to undergo RAT. Results We recruited 8856 individuals with diverse demographic, socioeconomic, and geographic characteristics in China. Eventually, 5388 participants (valid response rate of 60.84%; 52.32% [2819/5388] women; median age 32 years) were included in the analysis. Among the 5388 participants, 687 (12.75%) expressed hesitancy to undergo RAT and 4701 (87.25%) were willing to undergo RAT. Notably, those who were from the central region (adjusted odds ratio [aOR] 1.815, 95% CI 1.441-2.278) and those who received COVID-19 information from traditional media (aOR 1.544, 95% CI 1.279-1.863) were significantly more likely to report hesitancy to undergo RAT (both P<.001). However, those who were women (aOR 0.720, 95% CI 0.599-0.864), were older (aOR 0.982, 95% CI 0.969-0.995), had postgraduate education (aOR 0.612, 95% CI 0.435-0.858), had children (<6 years old) and elders (>60 years old) in the family (aOR 0.685, 95% CI 0.510-0.911), had better knowledge about COVID-19 (aOR 0.942, 95% CI 0.916-0.970), and had mental health disorders (aOR 0.795, 95% CI 0.646-0.975) were less likely to report hesitancy to undergo RAT. Conclusions Hesitancy to undergo SARS-CoV-2 RAT was low among individuals who were not yet infected with SARS-CoV-2. Efforts should be made to improve the awareness and acceptance of RAT among men, younger adults, individuals with a lower education or salary, families without children and elders, and individuals who access COVID-19 information via traditional media. In a reopening world, our study could inform the development of contextualized mass screening strategies in general and the scale-up of RAT in particular, which remains an indispensable option in emergency preparedness.

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Factors associated with reversals of COVID-19 vaccination willingness: Results from two longitudinal, national surveys in Japan 2021-2022

Cited by 17 publications

References 26 publications

Vaccination willingness, vaccine hesitancy, and estimated coverage of SARS‐CoV‐2 vaccine among healthcare workers in Tanzania: A call for action

Vaccination willingness, vaccine hesitancy, and estimated coverage of SARS‐CoV‐2 vaccine among healthcare workers in Tanzania: A call for action

Dynamic predictors of vaccination uptake over two years of the COVID-19 vaccination campaign: lessons from Hong Kong

Hesitancy to Undergo SARS-CoV-2 Rapid Antigen Testing in China: Nationwide Cross-sectional Study

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