Factors associated with survival in patients with meningioma

McCarthy, Bridget J.; Davis, Faith G.; Freels, Sally; Surawicz, Tanya; Damek, Denise; Grutsch, James F.; Menck, Herman R.; Laws, Edward R.

doi:10.3171/jns.1998.88.5.0831

Cited by 205 publications

(96 citation statements)

References 14 publications

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“…These survival rates are similar to the 5 year survival rates of people aged 0 – 44 years with benign and malignant meningiomas from the National Cancer Database from the United States of 89·1% and 65·1%, respectively. 21 …”

Section: Resultsmentioning

confidence: 99%

“…13, 21, 23, 36–38 None of the manuscripts included treatment of the subsequent meningiomas; this would likely consist of surgical resection which is the treatment of choice for primary meningiomas. 43 Fortunately, prior treatment exposures would be expected to have little impact upon successful treatment of the subsequent meningioma by complete surgical resection of the tumor.…”

Section: Discussionmentioning

confidence: 99%

“…Non-malignant meningiomas have only been included in the SEER registry since 2004; 20 therefore, the estimates of survival of people from the general population with meningiomas from 1985 – 1992 was derived from the study by McCarthy and colleagues of the National Cancer Data Base, which includes tumors from approximately 1000 hospitals participating in the American College of Surgeons’ tumor registry program. 21 …”

Section: Methodsmentioning

confidence: 99%

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Subsequent neoplasms of the CNS among survivors of childhood cancer: a systematic review

Bowers

Nathan

Constine

et al. 2013

The Lancet Oncology

100

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Childhood cancer survivors are at risk for development of subsequent neoplasms of the central nervous system (CNS). Better understanding of the rates, risk factors for and outcomes of subsequent neoplasms of the CNS among survivors of childhood cancer may lead to the development of more informed screening guidelines. Two independent investigators independently performed a systematic search of studies from the MEDLINE and EMBASE databases (1966 – 2012) for studies examining subsequent neoplasms of the CNS among childhood cancer survivors. Articles were selected to answer 3 questions: What is the risk of CNS tumors following radiation to the cranium for a pediatric cancer as compared with the general population? What are the outcomes in children with subsequent neoplasms of the CNS who have been treated with CNS directed radiation for a pediatric cancer? Are outcomes of subsequent neoplasms different from primary neoplasms of the same histology? Our search identified 72 reports, of which 18 publications were included in this review. These studies reported that childhood cancer survivors have an 8.1 – 52.3 times higher incidence of subsequent CNS neoplasms compared with the general population. Nearly all cancer survivors who developed a CNS neoplasm had been exposed to cranial radiation; some studies demonstrate a correlation between radiation dose and risk of subsequent CNS tumors. Five year survival rates for subsequent high-grade gliomas and meningiomas range from 0 – 19.5% and 73 – 100%, respectively, which are similar to those observed in patients with primary gliomas or meningiomas. The quality of evidence was limited by variation in study design, heterogeneity of details regarding treatment and outcomes, limited follow-up and relatively small sample sizes. We concluded that survivors of childhood cancer who were treated with cranial radiation therapy have an elevated risk for subsequent CNS neoplasms. The current literature is insufficient to comment about the potential harms and benefits of routine screening for subsequent CNS neoplasms.

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

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Subsequent neoplasms of the CNS among survivors of childhood cancer: a systematic review

Bowers

Nathan

Constine

et al. 2013

The Lancet Oncology

100

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“…Although the giant tumor in the CPA was resected gross totally, patient died due to lower cranial nerve deficits. Completeness of tumor removal is the most important factor to prevent tumor recurrences [7, 8, 20, 21]. All subtotally resected cases recurred after some period in this series, and 2 patients died because of recurrence.…”

Section: Discussionmentioning

confidence: 99%

“…Tumor location, completeness of tumor removal, and pathological grade are the most important prognostic factors for meningiomas [2, 7, 8, 20, 21]. The recurrence rate of meningiomas changes from one series to another.…”

Section: Discussionmentioning

confidence: 99%

Intracranial Meningiomas of Childhood and Adolescence

Tufan¹,

Doğulu²,

Kurt³

et al. 2005

Pediatr Neurosurg

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Meningiomas are rare intracranial neoplasms in childhood and adolescence, representing 0.4–4.1% of the pediatric-age tumors and 1.5–1.8% of all intracranial meningiomas. The goal of this study was to determine epidemiology, clinical and radiological features, and long-term outcome of childhood and adolescence meningiomas. Patients operated for intracranial meningiomas of childhood and adolescence between 1983 and 2003 at Gazi University School of Medicine, Department of Neurosurgery, were evaluated retrospectively. This study presents 11 cases (6 male, 5 female), ranging in age from 14 months to 17 years. Age and sex distribution, presenting symptoms, neurological examination results, location of meningiomas, radiological and histopathological findings, and prognosis were reviewed. The results were compared with those reported in the existing literature. Atypical and malignant meningiomas seem to be more common in childhood and adolescence with respect to adult meningiomas. Tumor location, completeness of tumor removal, and pathological grade are the most important prognostic factors.

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Primary and Metastatic Neoplasms of the Brain in Adults

DeAngelis

2017

Holland‐Frei Cancer Medicine

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Overview Primary brain tumors are uncommon but aggressive neoplasms even when histology is low grade. Secondary, or metastatic, tumors are at least 3 times more common than all primary tumors combined. Diagnosis is easily established by magnetic resonance imaging (MRI), and surgical resection provides histologic confirmation and decompression; surgery alone may suffice for low‐grade tumors and most extra‐axial tumors such as meningiomas. Treatment of parenchymal brain tumors, primary or metastatic, often requires a combination of radiotherapy and chemotherapy, which may improve patient function and control disease but rarely achieves cure.

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Factors associated with survival in patients with meningioma

Abstract: Although not population-based, the NCDB has the potential for providing pertinent information regarding patient characteristics and methods of treatment for benign, as well as malignant, brain tumors.

Cited by 205 publications

References 14 publications

Subsequent neoplasms of the CNS among survivors of childhood cancer: a systematic review

Subsequent neoplasms of the CNS among survivors of childhood cancer: a systematic review

Intracranial Meningiomas of Childhood and Adolescence

Primary and Metastatic Neoplasms of the Brain in Adults

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