Factors Associated with the Occurrence and Healing of Umbilical Pilonidal Sinus: A Rare Clinical Entity

Abstract

Objective: Pilonidal sinus disease (PSD) is a chronic inflammatory condition of skin that is thought to be related to implanted loose hair. Although PSD is most frequently seen in the sacrococcygeal region, it can also occur at the axilla, perineum, suprapubic regions, hands, and umbilicus. The aim of this project was to find factors influencing the development and treatment of umbilical PSD. Methods:In this retrospective study, the authors evaluated 82 patients (19 women, 63 men) with a history of umbilical PSD between 2012 and 2020 to determine predisposing factors and treatment modalities.Results: There was a 20% concordance with intergluteal PSD. Smoking was the only modifying factor for recurrence. The three different treatment methods studied (conservative treatment, surgical treatment, silver nitrate) did not differ in recurrence rate (P = .57). Conclusions:Because of its rare nature, umbilical PSD can be misdiagnosed or underdiagnosed. Key aspects of treatment include smoking cessation and a conservative approach.

CCND2 and miR-206 as potential biomarkers in the clinical diagnosis of thyroid carcinoma by fine-needle aspiration cytology

“…Diagnostic criteria for thyroid fine-needle aspiration were based on the guidelines of the Papanicolaou Society of Cytopathology, and divided into six types: (1) undiagnosed: there is a problem of sampling, so the cytological diagnosis cannot be carried out; (2) benign lesions: nonneoplastic diseases; (3) follicular lesions: tend to be benign lesions, but the possibility of tumors is not ruled out; (4) follicular tumors: adenoma or carcinoma; (5) suspected malignancy: have malignant cytological features, and undiagnosed; (6) malignant tumors [12].…”

“…In clinical diagnosis of thyroid nodules, the thyroid fine-needle aspiration method is commonly used. This method has the advantages of high safety, simple operation and low cost, and can accurately determine the nature of thyroid nodules, timely detect thyroid malignant tumors, and avoid surgical treatment for benign thyroid patients [3][4][5]. Numerous studies showed that microRNAs (miRNAs) and human cyclin D2 (CCND2) are implicated in tumorigenesis [6][7][8].…”

Intraoperative and Postoperative Outcomes of Modified Bidirectional Intra-Umbilical Incision versus Infra-Umbilical Incision for Direct Trocar Insertion in Gynaecological Laparoscopy

“…pilonidal sinus disease), previous laparoscopy or umbilical surgery and previously burned or hyperpigmented umbilicus. 10 Additionally, prepubertal or postmenopausal patients were also excluded from this study.…”

Pulmonary nodules, is there any pathogenesis evidence?

“…A number of clinical evidence was suggested at genetic, metabolism, therapeutic and nutrition levels after growing clinical study. [17][18][19][20][21] System comparisons and integration can help these discoveries. We may learn more about this mystery event in medicine and techniques in the future.…”