This article deals with commuting to and from work of workers in Slovakia as a part of traveling and its impact on private life of commuters. It provides a more comprehensive view on the socio-demographic determinants which affect the travel mode choice. Furthermore, the study offers several evaluations of the impact on the subjective well-being of commuters. The aim of the article is to review demographic and economic determinants influencing the travel mode choice and to determine its impact on the subjective well-being of respondents. On a sample of approximately 1000 economically active individuals by using several statistical tests (Nominal Logistic Regression, Fisher’s Exact Test, Mann-Whitney Test, Cochran Test, McNemar Test), we identified the determinants affecting the travel mode choice of respondents, including commuting time costs, commuting financial costs, income of respondents, education, gender, type of employment and place of work. This study has also showed that respondents are the most satisfied when commuting by bicycle or on foot and the most dissatisfied when commuting by using public transport. These facts, among others, should be reflected by the creation of sustainable and “green” transport infrastructure in Slovakia.