Factors Associated with Treatment Failure in Patients with Acute Exacerbation of COPD Admitted to the Emergency Department Observation Unit

Pethyabarn, Wasuntaraporn; Chewae, Sareeman; Dadeh, Ar-aishah

doi:10.1155/2020/8261375

Cited by 5 publications

(2 citation statements)

References 30 publications

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“…That means, initial treatments in ED observation unite had failure and prolonged length of stay in hospital. Similarly, according to retrospective study including 220 COPD patients, comorbidities like arrhythmias, diabetic mellitus and pneumonia findings on chest X-ray were factors associated to treatment failure 12 .…”

Section: Discussionmentioning

confidence: 99%

Factors Associated With Hospitalisation of Copd Exacerbations During a Winter Season In an Emergency Ward

Kabalak¹

2021

Dicle Tıp Dergisi

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Objectives: Chronic obstructive pulmonary disease (COPD) is a difficult chronic illness to manage because it causes prolonged hospital admissions and repeated applications. We aimed to examine the factors affecting this situation in a winter emergency in a chest diseases emergency. Material and Method: We conducted a retrospective study in our emergency department (ED) with patients who admitted due to COPD exacerbations. Factors affecting hospitalization and ICU requirement were evaluated.Results: Totally 128 patients were included. Mean number for ED admissions was 3.01±2.1. There were 73 (57%) hospitalized patients and 17(13.3%) patients transferred to intensive care unit (ICU). White blood cell (WBC) and C reactive protein (CRP) were significantly higher in patients with ≥3 ED admissions than others (p=0.06 and p=0.007 respectively). Among categorical variables being current smoker, long time oxygen therapy (LTOT) and non-invasive mechanical ventilation (NIMV) devices and existence of bronchiectasis were related to frequent ED admission (p=0.025, p=0.01, p=0.046 and p=0.028 respectively). Existence of pneumonia and comorbidities had positive and significant correlations with hospitalization (r=0.18, p=0.04 and r=0.26, p=0.02). In terms of ICU requirement, pneumonia, partial arterial pressure of carbon dioxide (PaCO2) value and mean pulmonary arterial pressure (PAB) had significant correlations (r=0.27, p=0.001, r=0.34, p<0.001 and r=0.24, p=0.006 respectively). Conclusion:The correct man.944321agement of the identified factors associated with recurrent emergency admission, service and ICU hospitalization in COPD patients should be done both at home and in the hospital.

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Section: Discussionmentioning

confidence: 99%

Factors Associated With Hospitalisation of Copd Exacerbations During a Winter Season In an Emergency Ward

Kabalak¹

2021

Dicle Tıp Dergisi

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“…This was also inferred in the total hospital charges, which were inflated for those patients with diabetes complications. This was seen even in an emergency department (ED) observation unit, as mentioned in a retrospective cohort study conducted in Thailand, where the patients with diabetes had increased odds of prolonged stay at the emergency department >48 h or COPD-related ED revisit within 72 h or readmission within one month [ 25 ].…”

Section: Discussionmentioning

confidence: 99%

The Impact of Diabetes Mellitus in Patients with Chronic Obstructive Pulmonary Disease (COPD) Hospitalization

Gunasekaran

Murthi

Elango

et al. 2021

JCM

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(1) Background: Chronic obstructive pulmonary disease (COPD) is the leading cause of morbidity and mortality worldwide. Diabetes mellitus (DM) has been shown to have adverse inflammatory effects on lung anatomy and physiology. We investigated the impact of DM on COPD patient outcomes during inpatient hospitalization. (2) Methods: We conducted a retrospective analysis using the Nationwide Inpatient Sample (NIS) over the years 2002–2014. Three groups, COPD without diabetes, COPD with diabetes but no complication, and COPD with DM and complication, were analyzed. (3) Results: A total of 7,498,577 were COPD hospitalization; of those, 1,799,637 had DM without complications, and 483,467 had DM with complications. After adjusting for clinical, demographic, and comorbidities, the odds of increased LOS in the COPD/DM with complication were 1.37 (confidence interval (CI): 1.326–1.368), and those of DM without complication were 1.061 (1.052–1.070) when compared with COPD alone. The odds of pneumonia, respiratory failure, stroke, and acute kidney injury were also higher in COPD hospitalizations with DM. Both DM with complication (odds ratio (OR): 0.751 (CI 0.727–0.777)) and DM without complication (OR: 0.635 (CI: 0.596–0.675)) have lesser odds of mortality during hospitalization than with COPD alone. (4) Conclusions: There is a considerable inpatient burden among COPD patients with DM in the United States.

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Clinical presentations and dispositions of transient ischemic attack and minor stroke patients at the emergency department of a tertiary hospital in southern Thailand: A retrospective study

Sakarin,

Liabsuetrakul

2024

Hong Kong j. emerg. med.

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ObjectiveTo assess the dispositions, management, and clinical outcomes of TIAMS patients in ED to improve the quality of management in ED.Material and MethodA descriptive retrospective study was conducted in ED patients aged >18 years diagnosed with TIAMS in the ED from 1 January 2018, to 31 January 2019. Data regarding terms of clinical presentation, examination, management, disposition, and adverse events were collected.ResultsThree hundred and sixty‐three TIAMS patients were enrolled in the study. Majority of the patients aged <45 years were admitted or referred (15.4%). The highest proportion of patients whose onset times from the last normal were less than 4.5 h were admitted to the EDOU (55.6%), while all patients whose onset times from the last normal were more than 48 h were discharged. Patients with abnormal cerebellar signs or atrial fibrillation were less likely to be discharged from the hospital. Patients with lower National Institutes of Health Stroke Scale (NIHSS) and ABCD2 scores tended to be discharged.ConclusionAmong TIAMS patients, age, symptom onset, presence of atrial fibrillation, positive cerebellar signs, and severity scores influenced the disposition. There was no difference in adverse events among disposition groups.

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Factors Associated with Treatment Failure in Patients with Acute Exacerbation of COPD Admitted to the Emergency Department Observation Unit

Cited by 5 publications

References 30 publications

Factors Associated With Hospitalisation of Copd Exacerbations During a Winter Season In an Emergency Ward

Factors Associated With Hospitalisation of Copd Exacerbations During a Winter Season In an Emergency Ward

The Impact of Diabetes Mellitus in Patients with Chronic Obstructive Pulmonary Disease (COPD) Hospitalization

Clinical presentations and dispositions of transient ischemic attack and minor stroke patients at the emergency department of a tertiary hospital in southern Thailand: A retrospective study

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