“…Doppler fluxometry applied to the uterine arteries allowed the confirmation of the hemodynamic disturbances underlying placental insufficiency, and demonstrated that in PE occurs an increased (circulatory) resistance of placental vascular territory (Papageorghiou & Leslie, 2007;Boukerrou et al, 2009). As changes in placental blood flow are observed in PE before the onset of symptoms (Papageorghiou & Leslie, 2007), uterine artery Doppler, is performed early in the second trimester of pregnancy, in order to predict PE.…”