Nursing education must undergo a digital transformation due to the COVID-19 pandemic. Nursing laboratory practices should be conducted virtually using suitable media and methods. This study aimed to assess the impact of Laboratory Learning with Peyton's 4-step approach through the social media platform Telegram on the bathing skills of nursing students. The research followed a quasi-experimental design with a pre-post approach and included a control group. The sample consisted of 60 nursing undergraduate students divided into treatment and control groups. The treatment group received a learning intervention using Peyton's 4-Step method via Telegram, while the control group was provided with a learning video. Instruments used included questionnaires and observation sheets developed by the researcher based on bathing skill procedures. The analyses employed the Mann-Whitney test and independent t-test, with a significance value set at <0.05. Peyton's approach via Telegram demonstrated a significant increase in students' knowledge (p=0.009) and skills (p=0.002) in bathing patients. Respondent characteristics, including gender, age, and school of origin, did not influence the results of the respondents' knowledge and skills in bathing patients (p>0.05). In conclusion, nursing education with Peyton's 4-step approach via Telegram offers an accessible platform for lecturers and students to engage in online discussions. Education can be conducted flexibly, anywhere, and anytime, with Telegram being a user-friendly social media platform.