Factors influencing antihypertensive medication compliance in Taiwan: a nationwide population-based study

Lee, Chien‐Ying; Huang, Chia‐Wei; Shih, Hung-Che; Huang, Kuang‐Hua

doi:10.1177/2047487312451252

Cited by 28 publications

(34 citation statements)

References 26 publications

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“…We also found that, in the upstream level, place of residence, education level, and health education were related to compliance behaviors of hypertensive patients. In this study, participants who lived in rural areas were less likely to comply with medication than those who lived in urban areas, which is consistent with a population-based study in Taiwan [ 50 ]. Generally, rural population had relatively low levels of income, education, and health service accessibility and utilization [ 51 ].…”

Section: Discussionsupporting

confidence: 90%

Prevalence and Associated Factors of Compliance Behaviors among Middle-Aged and Older Hypertensive Patients in China: Results from the China Health and Retirement Longitudinal Study

Liu

Yang

Zhou

et al. 2020

IJERPH

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Partial or total non-adherence has been recognized as major issues in the long-term management of hypertension. This study aims to investigate the prevalence and associated factors of compliance behaviors among Chinese middle-aged and older hypertensive patients. A sample of 6308 hypertensive patients aged ≥45 years was obtained from the 2015 China Health and Retirement Longitudinal Study (CHARLS) data. Two compliance behaviors were involved including medication and blood pressure monitoring. Stratified binary logistic regression analysis was employed to examine the associated factors. 77.2% of the participants reported medication compliance, and 40.7% complied with blood pressure monitoring. Better medication compliance associated with older age, overweight or obesity, one or ≥3 complications, no drinking, living in urban areas, and health education. Better blood pressure monitoring compliance associated with older age, overweight or obesity, ≥3 complications, normal activities of daily living (ADL), no smoking, sleep duration of 6–8 h, better cognitive function, living in urban areas, education level of middle school or above, and health education. Chinese middle-aged and older hypertensive patients experienced unoptimistic compliance behaviors, especially for blood pressure monitoring. Special attention and targeted interventions are urgent for the high-risk population of poor compliance behaviors, such as rural individuals, low educational population, and younger hypertensive patients.

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Section: Discussionsupporting

confidence: 90%

Prevalence and Associated Factors of Compliance Behaviors among Middle-Aged and Older Hypertensive Patients in China: Results from the China Health and Retirement Longitudinal Study

Liu

Yang

Zhou

et al. 2020

IJERPH

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“…This is consistent with other studies that show hypertensive patients have poor adherence to treatment [17-19], which may be the primary cause of uncontrolled hypertension [16]. On the other hand, there may be multiple reasons for nonadherence to medications such as poor access to healthcare, cost of medicine, etc.…”

Section: Discussionsupporting

confidence: 91%

Characteristics and Factors Associated With Antihypertensive Medication Use in Patients Attending Peruvian Health Facilities

Mejía

Failoc‐Rojas

et al. 2017

Cureus

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Introduction Hypertension is a very common disease worldwide, and medication is needed to prevent its short-term and long-term complications. Our objective was to determine the characteristics and factors associated with antihypertensive medication use in patients attending Peruvian health facilities.Materials & MethodsWe performed a multicenter, cross-sectional study with secondary data. We obtained self-reported antihypertensive medication from patients attending health facilities in 10 departments of Peru. We looked for associations of the antihypertensive treatment according to sociopathological factors and obtained p values using generalized linear models.ResultsOf the 894 patients with hypertension, 61% (547) were women and 60% (503) were on antihypertensive treatment, of which 82% (389) had monotherapy and 52% (258) had recently taken their medication. Antihypertensive treatment was positively correlated with the patient's age (adjusted prevalence ratio [aPR]: 1.01; 95% confidence interval [CI]: 1.007 to 1.017; p value < 0.001), diabetes (aPR: 1.31; 95% CI: 1.11 to 1.55; p value = 0.001) and cardiovascular disease (aPR: 1.38; 95% CI: 1.26 to 1.51; p value < 0.001). Conversely, the frequency of antihypertensive treatment decreases with physical activity (aPR: 0.80; 95% CI: 0.70 to 0.92; p value = 0.001).ConclusionPatients who have comorbidities and advanced age are more likely to be on antihypertensive treatment. In contrast, patients with increased physical activity have a lower frequency of antihypertensive treatment. It is important to consider these factors for future preventive programs and to improve therapeutic compliance.

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“…However, patients in our study had relatively lower adherence and persistence rate compared with existing studies (adjusted MPR; FDC vs. FC, at 6 month: 66.55% vs. 63.86%; at 1 year: 52.58% vs. 46.73%). These variations can be explained by the heterogeneity of patient population , variations of treatment employed and culture differences .…”

Section: Discussionmentioning

confidence: 99%

Adherence and medication utilisation patterns of fixed-dose and free combination of angiotensin receptor blocker/thiazide diuretics among newly diagnosed hypertensive patients: a population-based cohort study

Hsu

Hsiao

et al. 2014

Int J Clin Pract

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Factors influencing antihypertensive medication compliance in Taiwan: a nationwide population-based study

Abstract: Several patient- and institution-related factors may influence medication compliance. Therefore, for optimal outcomes, patients' awareness of the need for compliance with antihypertensive therapy must be enhanced, and effective intervention strategies should be developed.

Cited by 28 publications

References 26 publications

Prevalence and Associated Factors of Compliance Behaviors among Middle-Aged and Older Hypertensive Patients in China: Results from the China Health and Retirement Longitudinal Study

Prevalence and Associated Factors of Compliance Behaviors among Middle-Aged and Older Hypertensive Patients in China: Results from the China Health and Retirement Longitudinal Study

Characteristics and Factors Associated With Antihypertensive Medication Use in Patients Attending Peruvian Health Facilities

Adherence and medication utilisation patterns of fixed-dose and free combination of angiotensin receptor blocker/thiazide diuretics among newly diagnosed hypertensive patients: a population-based cohort study

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