Factors influencing the duration of pregnancy termination with vaginal misoprostol for fetal abnormality

Dickinson, Jan E.; Doherty, Dorota

doi:10.1002/pd.2236

Cited by 27 publications

(23 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A longer time interval in women with a previous caesarean section in the study of Wagner could be due to the absence of a previous spontaneous delivery [9]. In the study by Dickinson, higher maternal age was associated with an increased requirement for surgical intervention, which is consistent with the reports of Ashok et al [28]. Sak et al, studied the factors influencing the duration of misoprostol-induced abortion in the second trimester and found the induction-to-abortion interval to be longer in patients with hyperglycemia and advanced gestational age [30].…”

Section: Discussionsupporting

confidence: 83%

“…For example, there were three main factors which influenced the duration of the abortion in a study by Dickinson and Doherty. Increasing gestational age, nulliparity, and advanced maternal age were associated with prolongation of the abortion [28]. In the study by Wagner, the parameters with significant influence were gestational age at the time of induction, obstetric history, and nulliparity.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Does the presence of anhydramnios affect the duration of medical abortion?

Karapınar

Güngören²,

Dolapçıoğlu³

et al. 2016

Ginekol Pol

View full text Add to dashboard Cite

Objectives: The aim of the study was to determine whether anhydramnios affected the duration of medical abortion in cases with various indications as compared to cases with normal amniotic fluid volume. Material and methods:Patients who were admitted to our clinic because of medical abortion between January 2010-December 2013 were included in this retrospective study. A total of 32 pregnant women with anhydramnios (study group) and 67 pregnant women with normal amniotic fluid volume but with fetal abnormality (control group) were included in the study. Patient age, gravidity, parity, gestational age, previous delivery route, and duration of the abortion were recorded.Results: Mean duration of the abortion in the study group was 71.93 ± 47.51 h as compared to 79.08 ± 52.62 h in the control group. There were no statistically significant differences between the two groups in terms of duration of the abortion (p = 0.516). Also, we found no statistically significant differences in duration of the abortion with regard to previous delivery route (p = 0.220).Conclusions: There were no statistically significant differences between the study group and controls in terms of duration of the abortion. In addition, neither parity nor previous delivery route affected the duration of the abortion.

show abstract

Section: Discussionsupporting

confidence: 83%

Section: Discussionmentioning

confidence: 99%

Does the presence of anhydramnios affect the duration of medical abortion?

Karapınar

Güngören²,

Dolapçıoğlu³

et al. 2016

Ginekol Pol

View full text Add to dashboard Cite

show abstract

“…GA affects the entire abortion process, including the I-to-A interval and completion of abortion. While pregnancy termination before 17 weeks of gestation was associated with higher chances of incomplete abortion [24], the mean I-to-A interval increases by 4 h after 20 weeks' gestation [7]. Supporting previous data [7], our results indicated that TOP after 24 weeks was associated with an increased risk of prolonged I-to-A interval.…”

Section: Discussionsupporting

confidence: 81%

“…As mifepristone is not available in Turkey, misoprostol is the first-line abortifacient in most settings. Misoprostol, a prostaglandin E1 analogue, has been used for induction of abortion at second and third trimesters since 1997 [7]. Misoprostol has many advantages including stability at room temperature, ease of administration, different administration routes, and low cost.…”

Section: Introductionmentioning

confidence: 99%

The Utility of Feticide Procedure to Shorten the Induction-to-Abortion Interval in Medical Abortion

Akkurt

Yavuz

et al. 2018

Gynecol Obstet Invest

View full text Add to dashboard Cite

Aim: To evaluate the effect of intracardiac potassium chloride feticide procedure (FP) on the induction-to-abortion (I-to-A) interval for various indications in the termination of pregnancy. Method: Medically indicated abortions between 17 and 28 weeks’ gestation were retrospectively evaluated and allocated into 2 groups: Cases with (group 1, n = 58) or without an FP (group 2, n = 60). I-to-A intervals were compared across the groups, considering different baseline parameters and fetal abnormality categories. Results: There were no differences among the groups except in gestational age (GA; mean, 21.2 vs. 19.6 weeks, p = 0.01) in group 1. Overall, the I-to-A interval was shorter (900 ± 233 vs. 1,198 ± 375 min, p = 0.001) and prolonged medical abortion (I-to-A interval > 48 h) was less common (2% vs. 6%, p = 0.03) in group 1. The facilitating effect of FP persisted when indications were categorized as central nervous system, chromosomal, other structural abnormalities, and unclassified conditions. Logistic regression analyses demonstrated the following features to be associated with expulsion of fetus after 24-h: (1) advanced GA (> 24 week; aOR 6.9, 95% CI 3.24–14.72), (2) central nervous system abnormalities (aOR 5.3, 95% CI 2.6–11.4), (3) lack of feticide (aOR 3.67, 95% CI 2.24–10.72). Conclusion: FPs seem to shorten the I-to-A interval and decrease prolonged I-to-A interval rates. This facilitating effect remains unchanged for various medical indications.

show abstract

“…Knowledge about the abortion interval (AI) and associated influencing factors is important for counseling women who need termination of a second trimester pregnancy; however, few studies mention such findings [4,5], and the inclusion criteria in these studies merely includes cases with fetal anomalies or selected medical indications. Thus, the aim of this retrospective study was to estimate the AI in all enrolled women who needed medical termination by a combination of vaginal and oral misoprostol and to identify the factors that affect the AI.…”

Section: Introductionmentioning

confidence: 99%

Factors influencing the abortion interval of second trimester pregnancy termination using misoprostol

Ting

Peng

Lin

et al. 2015

Taiwanese Journal of Obstetrics and Gynecology

View full text Add to dashboard Cite

show abstract

Factors influencing the duration of pregnancy termination with vaginal misoprostol for fetal abnormality

Abstract: Three factors: nulliparity, younger maternal age and increasing gestation, were associated with abortion prolongation. Apart from musculoskeletal abnormalities, the fetal anomaly had no impact on abortion duration.

Cited by 27 publications

References 14 publications

Does the presence of anhydramnios affect the duration of medical abortion?

Does the presence of anhydramnios affect the duration of medical abortion?

The Utility of Feticide Procedure to Shorten the Induction-to-Abortion Interval in Medical Abortion

Factors influencing the abortion interval of second trimester pregnancy termination using misoprostol

Contact Info

Product

Resources

About