Factors influencing the length of hospital stay during the intensive phase of multidrug-resistant tuberculosis treatment at Amhara Regional State hospitals, Ethiopia: A retrospective follow up study

Tamirat, Koku Sisay; Andargie, Gashaw; Babel, Yaregal Animut

doi:10.21203/rs.3.rs-15610/v3

Cited by 1 publication

(2 citation statements)

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“…A semistructured interview was administered to 288 individuals, 72 cases, and 216 controls. In this study, the proportion of male participants in the cases (nonadhered TB patients) and controls (adhered TB patients) was 59.7% (43) and 63.4% (137) respectively (Table 2).…”

Section: Description Of the Socio-demographic And Economicmentioning

confidence: 69%

“…However, regional TB control and treatment success is daunting with myriads of complex factors. Incomplete treatment leads to prolonged excretion of bacteria that may resist the drugs, which causes increased morbidity and mortality and makes fertile ground for the spread of the disease [43]. Hence, assessment of the status of treatment outcomes and finding out the specific determinant factors which contribute to this unsuccessful treatment course are imperative for the welfare of Gambella regional state and Ethiopia's TB management program.…”

Section: Discussionmentioning

confidence: 99%

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Nonadherence Predictors to Tuberculosis Medications among TB Patients in Gambella Region of Ethiopia

Kebede

Jing

Girma

et al. 2022

Canadian Journal of Infectious Diseases and Medical Microbiolog

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Background. Global tuberculosis (TB) disease deaths rise comparable to the one seen in 2015 (by 200,000) or even in 2012 (by 400,000) as a result of the potential impact of the COVID-19 pandemic. Ethiopia’s Gambella region is leading for years in terms of TB cases and its comorbidities. The TB control program effectiveness depends on in large on the patients completing the appropriate treatment regimen. Hence, the objective of this study was to determine the determinants of nonadherence to anti-TB drug treatment among patients in Gambella regional state of Ethiopia. Methods. A case-control study was conducted on cohorts of TB patients sampled from four public health facilities in Gambella Region from January 2019 to 2020, followed by 18 months of follow-up. The total sample size was 296 patients (74 cases and 222 controls) with a response rate of 97.3% (288 : 72 nonadhered cases and 216 controls). Cases (nonadhered) were TB patients who missed 10% of the doses while controls were patients, who completed 90% or more doses. Results. TB patients, who perceived stigma [AOR = 2.7 at 95% CI (1.1–6.6) with P value <0.05], failed to receive any counseling during the treatment course [AOR = 65.24 at 95% CI (11.69–363.95) with P value <0.01], patients who used to smoking during treatment [AOR = 15.4 at 95% CI (7.7–30) with P value <0.01], taking TB medications regularly has no benefits [AOR = 6.8 at 95% CI (1.8–24.9) with P value <0.05], and patients believing TB disease as not severe [AOR = 8.38 at 95% CI (2.0–34.6) with P value <0.05] were significantly or highly significantly associated with nonadherence to anti-TB drugs medications. Conclusion. The determinants of nonadherence to anti-TB treatment among TB patients in the Gambella region during the study period were the absence of counselling services, and patients’ behavior (smoking habits, undermining the severity of TB disease, lack of trust in the outcomes of regular medications, and perceived stigmatization). Accordingly, capacitating healthcare providers and workers at all TB clinics for effective counseling , preventing perceived stigma by protecting the patient’s secrecy, and routine health education has paramount importance for effective TB control in Gambella.

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Section: Description Of the Socio-demographic And Economicmentioning

confidence: 69%

Section: Discussionmentioning

confidence: 99%