Factors influencing the occurrence of mammary gland tumours in dogs

Epidemiological, cytological, and haemato-serological analysis of canine mammary gland tumours

“…Breed distribution patterns vary, therefore breed predisposition also depends on the research area's geographic location. Genetics may have a part in the development of canine mammary tumours, as evidenced by the increased occurrence in purebred dogs compared to non-descript and cross-bred dogs (Sarli et al, 2002;Srivastava et al, 2009;Nithya et al, 2018) [25,27,18] . Older bitches that were more than six years of age were frequently affected animals.…”

“…This could be the result of posterior glands changing more proliferatively in response to hormonal influences, particularly oestrogen. Since these are the largest glands, there is a chance that they will experience more stress and physiological changes, which increases the susceptibility to develop mammary cancer (Nithya et al, 2018) [18] . Only 6 animals (14.28%) out of the 42 animals in the current study had undergone spaying, whereas 36 animals (85.72%) had not.…”

“…Mammary tumours account for about 52% of all tumour cases in dogs (Varallo et al, 2019) [29] . Most of these cases are documented in female dogs worldwide, with occasional occurrences of 1.7% to 8% occurring in male canines (Nithya et al, 2018) [18] . Since dogs grow a wide range of tumours with clinicopathological characteristics and incidence rates comparable to human cancers, they are an excellent model for comparative oncology.…”