Factors influencing the occurrence of multicentric and ‘recurrent’ Warthin's tumour: a cross sectional study

Ethunandan, M.; Pratt, C.; Higgins, Bernie; Morrison, A.; Umar, T.; Macpherson, D.W.; Wilson, A.

doi:10.1016/j.ijom.2008.05.001

Cited by 21 publications

(22 citation statements)

References 26 publications

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“…Similarly, in a retrospective, cross-sectional study, only 19% of multi-centric tumors were identified by palpation and only 28% by imaging investigations [15]. Recurrence rates for solitary and multi-centric tumors were 0 and 10%, respectively [15]. This same study also revealed that intraoperative rupture of the tumor was not associated with recurrence however, positive margins and multi-centricity were [15].…”

Section: Discussion:-mentioning

confidence: 69%

“…This same study also revealed that intraoperative rupture of the tumor was not associated with recurrence however, positive margins and multi-centricity were [15]. The authors consequently question whether "recurrence" is related to sub-clinical or unrecognized multicentric disease [15].…”

Section: Discussion:-mentioning

confidence: 86%

“…In one study, when parotidectomy specimens were examined with wholeorgan sectioning, 50% had multiple tumors [14]. Similarly, in a retrospective, cross-sectional study, only 19% of multi-centric tumors were identified by palpation and only 28% by imaging investigations [15]. Recurrence rates for solitary and multi-centric tumors were 0 and 10%, respectively [15].…”

Section: Discussion:-mentioning

confidence: 99%

“…A definitive diagnosis is usually rendered when FNA reveals monolayered sheets of oncocytic cells, lymphocytes, and amorphous, cystic debris [13]. Management options for solitary lesions include conservative management with observation [16] or resection with either local excision or parotidectomy [15]. Multi-centric and bilateral disease is not uncommon but it is often subclinical and not easily detected by palpation or imaging [15].…”

Section: Conclusion:-mentioning

confidence: 99%

“…When surgery is elected, some researchers recommend local excision be limited to patients with solitary tumors and that multi-centric tumors be addressed with superficial parotidectomy [15]. Because these tumors have a less than a 1% chance of malignant transformation, once recurrent disease is confirmed with FNA cytology, surgery can be offered, however, conservative management with observation is not necessarily contraindicated [16].…”

mentioning

confidence: 99%

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Recurrent Warthin Tumor Presenting With Synchronous, Bilateral Parotid and Multi-Centric Upper Neck Involvement.

Ghafouri¹

2018

IJAR

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Background: Warthin tumor is the second most common benign salivary tumor. This case highlights a patient who underwent local excision of a solitary Warthin tumor from the peri-parotid area. He subsequently presented with recurrent, multi-centric disease with bilateral parotid and cervical lymph node involvement. Case Report: A 45 year old, tobacco-using male was referred for a right head and neck mass. Exam revealed a mobile, painless mass near the angle of the jaw.Nasofibroscopic exam revealed a non-obstructive nasopharyngeal mass. CT confirmed an ovoid mass inferior to the right parotid gland. Fine-needle aspiration (FNA) was non-diagnostic. Deep biopsies and local excision of the right neck mass were performed. Nasopharyngeal biopsies were negative; the neck mass was consistent with Warthin tumor. The patient returned approximately 4 years later with a right pre-auricular mass and right upper neck lymphadenopathy. Diagnostic work-up, including ultrasound-guided FNA, revealed bilateral parotid gland Warthin tumor. The patient was symptomatic from the right-sided disease and not the left. Consequently, he elected right parotidectomy and excision of the right upper neck lymph nodes and clinical follow-up of the left mass. Upon pathologic review, there was Warthin tumor present in the parotidectomy and right lymph node specimens.

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Section: Discussion:-mentioning

confidence: 69%

Section: Discussion:-mentioning

confidence: 86%