Klimes J., P. Jagos, J. Bouda, S. Gajdusek: Basic Qualitative Parameters of Cow Colostrum and their Dependence on Season and Post ParIum Time. Acta vet. Hrno, 55,1986: 23-39.Under conditions of large scale' dairy unit for 2144 cows 19 physicochemical and biochemical parameters of cow colostrum and the influence of season and time after parturition on these parameters have been studied. Average samples of colostrum from the first milking, on the 3rd and 5th day post parturition were collected from cows -cross-breds of Bohemian Pied x Black Pied Lowland breeds. In summer (June) and winter (February) season colostrum of 13 and 24 cows, resp. was examined.In most parameters the highest values were found in colostrum from the first milking, the most pronounced decrease being observed for the first three days after parturition. Only the pH and lactose values were found to be lowest in colostrum from the first milking. The fat content, rennet coagulation time of colostrum and potassium concentration varied without a marked dependence upon the time elapsed after parturition. In summer season, significantly higher values of vitamin A, buffer capacity and dry matter were ob'served in at least two out of three investigated milkings; in winter, significantly higher phosphorus levels were found.• Approximately 1000 times higher GMT activity when compared with that in cow blood plasma was demonstrated in colostral whey.Higher titratable acidity, higher levels of protein, gamma globulins, sodium, GMT activity and lower lactose concentration were determined in colostrum samples from the first milking with a concentration of total protein in whey over 120 gil, when compared with colostrum with a decreased total protein content in whey.The determination of total protein concentration in colostral whey from the first milking could be regarded as a decisive criterion of the evaluation of colostrum quality. On the basis of colostrum quality the level of nutrition, maintenance, and health condition of mother in the last gravidity trimester may be assessed together with other factors which will influence further development of the calves.