Factors Involved in Antibody Formation

Antigenically–Induced Changes in Lymph Nodes during the Primary Antibody Response

“…Thus it is not improbable that an RNA fraction built by macrophages throughout the organism, including those in lymph nodes, may find its way into the antibody forming cells. This RNA could transfer information for the synthesis of antibody globulins or may activate antibody molecules or fractions there of [15,16]. Further work will be necessary to establish whether or not these RNA fractions which have been found to be envolved in the immune response are identical and whether this fraction or fractions 544 R ifé Antigenically-Induced Changes arc the ones responsible for the base changes reported here.…”

“…Further work will be necessary to establish whether or not these RNA fractions which have been found to be envolved in the immune response are identical and whether this fraction or fractions 544 R ifé Antigenically-Induced Changes arc the ones responsible for the base changes reported here. The unexpected increase in RNA concentration in the liver may be partly due to dietary factors such as glycogen depletion, but it is of interest to recall in connection with this that the highly active nuclcoprotein complex found by Campbell and Garvey [15] was isolated from the liver.…”