Facts and Figures on Covid-19 Pandemic Outbreak

Muneer, M. A.; Munir, Khalid; Abbas, Ghulam; Munir, Isra; Khan, Mumtaz Ahmad; Iqbal, Asif; Ahmad, Munsoor ud Din; Javid, Muhammad Arshad; Fatima, Zareen; Arshad, Muhammad Junaid

doi:10.17582/journal.pjz/20200913170904

Cited by 3 publications

(3 citation statements)

References 11 publications

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“…Additionally, upon observing the binding modes of ACE2-SARS-CoV-2 S-protein in human and snake, three regions of snake ACE2 with large structural differences were observed. Within these regions, one compact yet complicated polar interaction network was formed between hACE2 and the S-protein of SARS-CoV-2, yet these polar contacts were not present in snake ACE2, which is the main reason for the reduced ability of snake ACE2 to bind SARS-CoV-2 [98][99][100][101][102]. Further to this, Luan et al [91] have generated structural simulations showing several key contacts of hACE2 with SARS-CoV-2 RBD and found that in snake ACE2, these contacts were completely eradicated.…”

Section: Snakementioning

confidence: 99%

Structural Bases of Zoonotic and Zooanthroponotic Transmission of SARS-CoV-2

Clayton

Ackerley

Aelmans

et al. 2022

Viruses

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The emergence of multiple variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) highlights the importance of possible animal-to-human (zoonotic) and human-to-animal (zooanthroponotic) transmission and potential spread within animal species. A range of animal species have been verified for SARS-CoV-2 susceptibility, either in vitro or in vivo. However, the molecular bases of such a broad host spectrum for the SARS-CoV-2 remains elusive. Here, we structurally and genetically analysed the interaction between the spike protein, with a particular focus on receptor binding domains (RBDs), of SARS-CoV-2 and its receptor angiotensin-converting enzyme 2 (ACE2) for all conceivably susceptible groups of animals to gauge the structural bases of the SARS-CoV-2 host spectrum. We describe our findings in the context of existing animal infection-based models to provide a foundation on the possible virus persistence in animals and their implications in the future eradication of COVID-19.

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Section: Snakementioning

confidence: 99%

Structural Bases of Zoonotic and Zooanthroponotic Transmission of SARS-CoV-2

Clayton

Ackerley

Aelmans

et al. 2022

Viruses

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“…Covid-19 Epidemiology: On December 31, 2019, the World Health Organization (WHO) was notified of a cluster of unidentified pneumonia cases in Wuhan City, Hubei Province, China. In the first cluster of samples, a new coronavirus was discovered and this novel virus then spread from China to twenty other countries by the end of 2019, with incidents reported on all continents except Antarctica (Muneer et al, 2021;Zahid and Perna, 2021).…”

Section: Introductionmentioning

confidence: 99%

Insight of Pandemic Covid-19: Developments and Challenges

M. A. Muneer,

M. Arshad,

G. Abbas

et al. 2023

PJS

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This review focuses on the characteristics of coronavirus disease-19 (COVID-19)including virus structure, ecoepidemiology and pathophysiology, signs and symptoms in infectedpeople, and data on virus pathogenicity, severity, and survivability in COVID-19 infected patients. Theemphasis is on immunological reactions, diagnosis, prophylactic methods, and the zoonoticsignificance of COVID-19. The authors feel that the review's contents will be valuable toepidemiologists, virologists, public health officials, diagnosticians, laboratory workers,environmentalists, and socioeconomic experts. It has information on the many types of coronavirusvariants, the disease situation in Pakistan and the WHO criteria for COVID-19 prevention is given.Moreover, lessons learned from the COVID-19 pandemic are also outlined.

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“…WHO established Greek-letter nomenclature for variants and classified them into three groups: variants under monitoring, variants of interest (VOI) and, most importantly, variants of concern (VoC), which demonstrated increased transmissibility and pathogenicity or decreased countermeasures efficiency (WHO, 2022b). The emergence of novel variants raised concerns about vaccines efficacy, which were later confirmed by a number of variants demonstrating different degrees of immune evasion ( Altmann et al, 2021 , Jangra et al, 2021 , Munir et al, 2021 , Singh et al, 2021 , Wang et al, 2021 ).…”

Section: Introductionmentioning

confidence: 99%