Faecal and Urinary Incontinence after Multimodality Treatment of Rectal Cancer

Lange, Marilyne M.; Velde, Cornelis J.H. van de

doi:10.1371/journal.pmed.0050202

Cited by 33 publications

(22 citation statements)

References 29 publications

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“…Interestingly, our analysis showed that, following sphinctersparing surgery, a statistically significant improvement of bowel continence compared to baseline occurred 3 years after surgery. Although this is in line with previous studies suggesting an improvement in anorectal function after 12 to 18 months from low anterior resection (46)(47)(48), we recommend caution when interpreting these results. Indeed, the absolute changes in the IS over time were especially small and, even if a statistically significant difference was found at 3 years, this may not necessarily reflect clinically relevant changes in bowel continence at this specific time point.…”

Section: Discussionsupporting

confidence: 91%

Short- and Long-Term Quality of Life and Bowel Function in Patients With MRI-Defined, High-Risk, Locally Advanced Rectal Cancer Treated With an Intensified Neoadjuvant Strategy in the Randomized Phase 2 EXPERT-C Trial

Sclafani

Peckitt

Cunningham

et al. 2015

International Journal of Radiation Oncology*Biology*Physics

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Section: Discussionsupporting

confidence: 91%

Short- and Long-Term Quality of Life and Bowel Function in Patients With MRI-Defined, High-Risk, Locally Advanced Rectal Cancer Treated With an Intensified Neoadjuvant Strategy in the Randomized Phase 2 EXPERT-C Trial

Sclafani

Peckitt

Cunningham

et al. 2015

International Journal of Radiation Oncology*Biology*Physics

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“…Evidence‐based treatment guidelines are lacking for postsurgical incontinence in CRC survivors; thus, recommendations are based on interventions used in the general population. Kegel exercises can be helpful for stress incontinence due to pelvic floor dysfunction, but pelvic floor strengthening may be limited if denervation occurred during surgery . Other conservative therapies, such as dietary modification (limiting caffeine and fluid intake) or medications, may also be useful.…”

Section: Assessment and Management Of Physical And Psychosocial Long‐mentioning

confidence: 99%

American Cancer Society Colorectal Cancer Survivorship Care Guidelines

El-Shami

Oeffinger

Erb

et al. 2015

CA A Cancer J Clinicians

365

316

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Colorectal cancer (CRC) is the third most common malignant disease in the United States (U.S.). Almost two-thirds of CRC survivors are living 5 years following diagnosis. The prevalence of CRC survivors is likely to increase dramatically over the coming decades with further advances in early detection and treatment and the aging and growth of the U.S. population. Survivors are at risk for a CRC recurrence, a new primary CRC, other cancers, as well as both short and long-term adverse effects of the CRC and the modalities used to treat it. CRC survivors may also have psychological, reproductive, genetic, social, and employment concerns following treatment. Communication and coordination of care between the treating oncologist and the primary care clinician is critical to effectively and efficiently manage the long-term care of CRC survivors. The following guidelines are intended to assist primary care clinicians in delivering risk-based health care for CRC survivors who have completed active therapy.

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“…Patients with LARS often rely on strategies such as the use of pads, self‐medication with laxatives and changes to diet in an attempt to control symptoms . Biofeedback can be used to help patients to improve evacuation or incontinence and is often the first‐line treatment option.…”

Section: Introductionmentioning

confidence: 99%

Acceptability and benefit of rectal irrigation in patients with low anterior resection syndrome: a qualitative study

et al. 2018

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Qualitative interview findings suggest rectal irrigation is an acceptable method of treatment for LARS. Participants who perceived their symptoms to be more severe or poorly controlled were most likely to consider rectal irrigation as a treatment option. The patients who completed treatment reported improvements in their QoL, the ability to control the time of defaecation being the key benefit CONCLUSION: Clinicians should consider offering rectal irrigation as a treatment option to patients presenting with bowel dysfunction following anterior resection as it can improve symptoms. Patients who perceive that their symptoms are severe are more likely to consider treatment. This article is protected by copyright. All rights reserved.

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Faecal and Urinary Incontinence after Multimodality Treatment of Rectal Cancer

Abstract: Marilyne Lange and Cornelis van de Velde discuss the differential diagnosis and management of incontinence after rectal cancer treatment.

Cited by 33 publications

References 29 publications

Short- and Long-Term Quality of Life and Bowel Function in Patients With MRI-Defined, High-Risk, Locally Advanced Rectal Cancer Treated With an Intensified Neoadjuvant Strategy in the Randomized Phase 2 EXPERT-C Trial

Short- and Long-Term Quality of Life and Bowel Function in Patients With MRI-Defined, High-Risk, Locally Advanced Rectal Cancer Treated With an Intensified Neoadjuvant Strategy in the Randomized Phase 2 EXPERT-C Trial

American Cancer Society Colorectal Cancer Survivorship Care Guidelines

Acceptability and benefit of rectal irrigation in patients with low anterior resection syndrome: a qualitative study

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