2013
DOI: 10.1016/j.mib.2013.06.003
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Faecalibacterium prausnitzii and human intestinal health

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Cited by 918 publications
(736 citation statements)
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References 59 publications
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“…12,13 Butyrate is known 110 to be an important energy source for colonocytes, and is suggested to enhance intestinal 111 barrier function. 14 Moreover, butyrate is known to possess anti-inflammatory properties 112 and even possible anti-cancer effects.…”
Section: A C C E P T E D Accepted Manuscriptmentioning
confidence: 99%
See 1 more Smart Citation
“…12,13 Butyrate is known 110 to be an important energy source for colonocytes, and is suggested to enhance intestinal 111 barrier function. 14 Moreover, butyrate is known to possess anti-inflammatory properties 112 and even possible anti-cancer effects.…”
Section: A C C E P T E D Accepted Manuscriptmentioning
confidence: 99%
“…14 Moreover, butyrate is known to possess anti-inflammatory properties 112 and even possible anti-cancer effects. [10][11][12]15 In addition, the 'healthy gut microbiome ' 113 plays an important role in the development of a balanced immune-system. A certain level 114 of immunological tolerance exists for the intraluminal bacteria in a healthy gut.…”
Section: A C C E P T E D Accepted Manuscriptmentioning
confidence: 99%
“…Recently, a number of studies have associated a 68 decreased abundance of this bacterium in the gut with several human diseases. Among others, 69 the low levels of F. prausnitzii have been detected in inflammatory bowel disease, celiac 70 disease, obesity and diabetes (reviewed in (Miquel et al, 2013), all of which are characterized 71 either by food intolerance, inadequate calorie intake and/or abnormal energy metabolism.…”
mentioning
confidence: 99%
“…Bacterial metabolites and hypoxia Bacterial metabolites, for example short chain fatty acids such as butyrate, are taken up by the host cells and used as an energy source. A decrease in butyrate-producing bacteria has been associated with IBD (reviewed in Miquel et al, 2013). Culture supernatants of bacteria and isolated metabolites, especially butyrate, induce wideranging changes in gene expression in intestinal organoids (Lukovac et al, 2014).…”
Section: Pattern Recognitionmentioning
confidence: 99%