In the hot rolling process, rolls with grooves are used for the production of various simple and complex profiles. Main factors influencing the fatigue life of these rolls result from the technological process of the rolling. Rolling speed is an important parameter of technological process which has great influence on overall production. In order to increase rolling production, an analysis of the rolling speed influence on the fatigue life of the rolls has been carried out. The fatigue life estimation is carried out according to the fatigue life stress concept based on the local stress. Stress spectra in critical areas are determined for three different roll speeds. The analysis shows that although increasing the rolling speed causes decrease of the fatigue life of the roll, the stresses caused by the rolling at the highest speed should not lead to roll fracture.