In order to study and design a high-strength suspension clamp suitable for a transmission line with a large transmission span, a finite element model of a high-strength suspension clamp for a transmission line with a large transmission span was established, and the high-strength suspension clamp was designed by using computational software to simulate and calculate the composition of high-strength materials. The results show that the cast iron overhang wire clamp in the transmission line with large span has safety risks, and the high strength overhang wire clamp designed in the study can effectively reduce the safety risks. The results show that the cast iron overhang wire clamp in the transmission line with large span has safety risks, and the high strength overhang wire clamp designed in the study can effectively reduce the safety risks.